Zu "K01869" wurden 68 Artikel gefunden!
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AN2718
Artikelnummer: TGM-T4040-100mg
Description: AN2718 inhibits protein synthesis through the OBORT mechanism and displays broad antifungal effectiveness. Target: Antifungal. Smiles: OB1OCC2=CC(Cl)=CC=C12. References: Aditya K Gupta., et al. InvestigatioN/Al drugs for onychomycosis. Expert Opin Investig Drugs. 2014 Jan,23(1):97-106.
| Anwendung: | LARS inhibitor |
| CAS | 174672-06-1 |
| MW: | 168.39 D |
ab 43,00 €
Epetraborole hydrochloride
Artikelnummer: TGM-T4045-10mg
Description: Epetraborole hydrochloride (GSK2251052 hydrochloride) is a potent and selective leucyl-tRNA synthetase inhibitor. Target: Antibacterial. Smiles: Cl.NC[C@H]1OB(O)c2c1cccc2OCCCO. References: Goldstein EJ, et al. Comparative in vitro activities of GSK2251052, a novel boron-containing leucyl-tRNA synthetase...
| Schlagworte: | GSK2251052 hydrochloride |
| Anwendung: | Potent, selective leucyl-tRNA synthetase inhibitor |
| CAS | 1234563-16-6 |
| MW: | 273.52 D |
ab 55,00 €
Anti-Leucyl tRNA synthetase / LARS
Artikelnummer: NSJ-RQ4955
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the...
| Schlagworte: | Anti-LARS, Anti-LeuRS, Anti-KIAA1352, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Leucine--tRNA ligase, cytoplasmic,... |
| Anwendung: | WB, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
772,00 €
Anti-LARS2
Artikelnummer: ATA-HPA045450.100
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 88%
| Schlagworte: | Anti-LeuRS, Anti-LARS2, Anti-KIAA0028, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Probable leucine--tRNA ligase,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 358,00 €
Anti-LARS
Artikelnummer: A304-315A
Protein function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs. [The UniProt...
| Schlagworte: | Anti-LARS, Anti-LeuRS, Anti-KIAA1352, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Leucine--tRNA ligase, cytoplasmic |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
Anti-LARS
Artikelnummer: A304-316A
Protein function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs. [The UniProt...
| Schlagworte: | Anti-LARS, Anti-LeuRS, Anti-KIAA1352, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Leucine--tRNA ligase, cytoplasmic |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 178,00 €
AN2718
Artikelnummer: Cay20708-1
AN2718 is a benzoxaborole compound that displays broad antifungal effectiveness in vitro. It inhibits leucyl-tRNA synthetase (LeuRS) from molds and yeasts (IC50s = 2 and 4.2 µM for A. fumigatus and C. albicans LeuRS, respectively), blocking protein synthesis.Formal Name:...
| Schlagworte: | 5-chloro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole |
| Anwendung: | LARS inhibitor |
| CAS | 174672-06-1 |
| MW: | 168.4 D |
ab 52,00 €
AN3365 (hydrochloride)
Artikelnummer: Cay20572-1
AN3365 is an inhibitor of leucyl-tRNA synthetase (LeuRS, IC50 = 0.31 µM for the E. coli enzyme). It is active against a variety of Gram-negative and Gram-positive bacteria, including E. coli, E. faecalis, S. epidermidis, S. pneumoniae, and S. pyogenes (MICs = 4, 8, 2, 2, and 2 µg/ml, respectively), as well as a...
| Schlagworte: | Epetraborole, GSK2251052, 3-[[(3S)-3-(aminomethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaborol-7-yl]oxy]-1-propanol,... |
| Anwendung: | Potent, selective leucyl-tRNA synthetase inhibitor |
| CAS | 1234563-16-6 |
| MW: | 273.5 D |
ab 52,00 €
Anti-LARS2
Artikelnummer: ATA-HPA035951.100
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 86%
| Schlagworte: | Anti-LeuRS, Anti-LARS2, Anti-KIAA0028, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Probable leucine--tRNA ligase,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-LARS
Artikelnummer: ATA-HPA036424.100
Protein function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs. [The UniProt...
| Schlagworte: | Anti-LeuRS, Anti-KIAA1352, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Leucine--tRNA ligase, cytoplasmic |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
Anti-CDC60
Artikelnummer: CSB-PA338765XA01SVG.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-LeuRS, Anti-CDC60, Anti-P2564, Anti-YPL160W, EC=6.1.1.4, Anti-Leucyl-tRNA synthetase, Anti-Leucine--tRNA ligase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
ab 1.529,00 €
Anti-leuS
Artikelnummer: CSB-PA357219XA01ENV.2
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-LeuRS, Anti-b0642, Anti-Leucine--tRNA ligase, Anti-Leucyl-tRNA synthetase, leuS Antibody |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Escherichia coli (strain K12) |
ab 1.529,00 €