Zu "K01648" wurden 111 Artikel gefunden!
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Anti-Recombinant ATP Citrate Lyase, clone A772
Artikelnummer: E-AN302052L.100
ATP-citrate lyase (ACL) is a homotetramer that catalyzes the formation of acetyl-CoA and oxaloacetate (OAA) in the cytosol, which is the keystep for the biosynthesis of fatty acids, cholesterol and acetylcholine, as well as for glucogenesis. Nutrients and hormones regulate theexpression level and phosphorylation of...
| Schlagworte: | Anti-ACLY, Anti-ATP-citrate synthase, Anti-Citrate cleavage enzyme, Anti-ATP-citrate (pro-S-)-lyase, Recombinant ATP... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
MitoCheck(R) Citrate Synthase Activity Assay Kit
Artikelnummer: Cay701040-96
The condensation of the dicarboxylate oxaloacetate and acetyl CoA to the tricarboxylate citrate is catalyzed by citrate synthase. It is within this reaction that carbon molecules (as acetyl CoA) obtained from pyruvate oxidation are fed into the tricarboxylic acid (TCA or citric acid) cycle. As a mitochondrial...
| Schlagworte: | ACL, ACLY, EC=2.3.3.8, ATP-citrate synthase, Citrate cleavage enzyme, ATP-citrate (pro-S-)-lyase |
| Anwendung: | Citrate synthas activity determination |
647,00 €
BMS 303141
Artikelnummer: Cay16239-5
ATP citrate lyase (ACL) catalyzes the synthesis of acetyl-CoA and oxaloacetate using citrate, CoA, and ATP as substrates and Mg2+ as a cofactor. The ACL-dependent synthesis of acetyl-CoA is important for the de novo synthesis of fatty acids and cholesterol. Furthermore, as a key enzyme for linking glucose and lipid...
| Schlagworte: | 3,5-dichloro-2-hydroxy-N-(4-methoxy[1,1'-biphenyl]-3-yl)-benzenesulfonamide |
| Anwendung: | ATP citrate lyase (ACL) inhibitor |
| CAS | 943962-47-8 |
| MW: | 424.3 D |
ab 139,00 €
ACLY Assay Kit
Artikelnummer: BPS-79904
ATP citrate lyase (ACLY) is an important enzyme in fatty acid synthesis and cancer metabolism. The ACLY Assay Kit is designed to measure ACLY activity for screening and profiling applications using ADP-Glo(R) Kinase Assay as a detection reagent.
| Schlagworte: | ACL, ACLY, ATP-citrate synthase, Citrate cleavage enzyme, ATP-citrate (pro-S-)-lyase |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
975,00 €
SB 204990
Artikelnummer: Cay15245-1
SB 204990 is a cell-permeable prodrug form of SB 201076, an inhibitor of ATP citrate lyase. SB 204990 inhibits fatty acid and cholesterol synthesis in HepG2 cells in a concentration-dependent manner. Oral administration of SB 204990 (25 mg/kg) reduces plasma levels of the lipoproteins VLDL, LDL, and HDL by 21, 40,...
| Schlagworte: | (3R,5S)-rel-5-[6-(2,4-dichlorophenyl)hexyl]tetrahydro-3-hydroxy-2-oxo-3-furanacetic acid |
| Anwendung: | ATP-citrate synthase (ACLY) inhibitor |
| CAS | 154566-12-8 |
| MW: | 389.3 D |
ab 67,00 €
Anti-ACL
Artikelnummer: A303-866A
Protein function: ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. [The UniProt Consortium]
| Schlagworte: | Anti-ACL, Anti-ACLY, EC=2.3.3.8, Anti-ATP-citrate synthase, Anti-Citrate cleavage enzyme, Anti-ATP-citrate (pro-S-)-lyase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
ATP Citrate Lyase, active human recombinant protein
Artikelnummer: BPS-50255
Active human ATP citrate lyase (ACLY) (GenBank Accession No. NM_001096), full length, with Nterminal GST tag, MW=147 kDa, expressed in baculovirus expression system.
| Schlagworte: | ACL, ACLY, ATP-citrate synthase, Citrate cleavage enzyme, ATP-citrate (pro-S-)-lyase, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 147 kD |
812,00 €
Anti-ATP Citrate Lyase, clone 3D9-E9-H8, C-terminal
Artikelnummer: ARG54041.100
Protein function: ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. [The UniProt Consortium]
| Schlagworte: | Anti-ACL, Anti-ACLY, EC=2.3.3.8, Anti-ATP-citrate synthase, Anti-Citrate cleavage enzyme, Anti-ATP-citrate (pro-S-)-lyase |
| Anwendung: | WB, ICC, IF, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, monkey |
658,00 €
Anti-ACL
Artikelnummer: A303-867A
Protein function: ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. [The UniProt Consortium]
| Schlagworte: | Anti-ACL, Anti-ACLY, EC=2.3.3.8, Anti-ATP-citrate synthase, Anti-Citrate cleavage enzyme, Anti-ATP-citrate (pro-S-)-lyase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Antimycin A2
Artikelnummer: Cay21997-500
Antimycin A2 is a component of the antimycin A complex (Cay-34799) and an inhibitor of ATP-citrate lyase (Ki = 4.2 µM).Formal Name: (2R,3S,6S,7R,8R)-3-(3-formamido-2-hydroxybenzamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate. CAS Number: 27220-57-1. Molecular Formula: C27H38N2O9. Formula Weight:...
| Schlagworte: | (2R,3S,6S,7R,8R)-3-(3-formamido-2-hydroxybenzamido)-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl butyrate |
| Anwendung: | ATP-citrate lyase inhibitor, antibiotic |
| CAS | 27220-57-1 |
| MW: | 534.6 D |
ab 444,00 €
Human ATP citrate lyase / ACLY ELISA Kit
Artikelnummer: G-HUFI01295.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Mouse ATP citrate lyase / ACLY ELISA Kit
Artikelnummer: G-MOFI00419.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €