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S1PL-IN-31
S1PL-IN-31

Artikelnummer: Cay39826-1

S1PL-IN-31 is an inhibitor of sphingosine-1-phosphate (S1P) lyase (IC50 = 210 nM). It is also an antagonist of the Smoothened (Smo) receptor (IC50 = 440 nM). In vivo, S1PL-IN-31 (2 mg/kg per day) prevents cervical and thoracic lymphocyte infiltration and neuromuscular weakness in a rat model of experimental...
Schlagworte: S1P Lyase Inhibitor 31, S1PL Inhibitor 31, Sphingosine-1-Phosphate Lyase Inhibitor 31,...
Anwendung: S1P lyase inhibitor
CAS 1538574-95-6
MW: 455 D
ab 93,00 €
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-10 %
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Mouse SGPL1 (Sphingosine 1 Phosphate Lyase 1) ELISA Kit
Mouse SGPL1 (Sphingosine 1 Phosphate Lyase 1) ELISA Kit

Artikelnummer: ELK-ELK6869.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SGPL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SGPL1. Next,...
Schlagworte: S1PL, mSPL, SPL 1, SP-lyase 1, Sphingosine-1-phosphate lyase 1, Sphingosine-1-phosphate aldolase
Anwendung: ELISA
Spezies-Reaktivität: mouse
365,00 € ab 328,50 €
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Sphingosine-1-Phosphate Lyase Fluorogenic Substrate
Sphingosine-1-Phosphate Lyase Fluorogenic Substrate

Artikelnummer: Cay13238-1

S1P lyase fluorogenic substrate is a substrate of S1P lyase, leading to the production of the fluorescent product umbelliferone (7-hydroxycoumarin) under appropriate conditions. This compound is intended to be used to monitor or measure S1P lyase activity.Formal Name:...
Schlagworte: S1P Lyase Fluorogenic Substrate, 2S-ammonio-3R-hydroxy-5-((2-oxo-2H-chromen-7-yl)oxy)pentyl hydrogen phosphate
Anwendung: S1P lyase activity measurement
CAS 1166838-84-1
MW: 359.3 D
ab 274,00 €
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2-Acetyl-5-tetrahydroxybutyl Imidazole
2-Acetyl-5-tetrahydroxybutyl Imidazole

Artikelnummer: Cay13222-1

2-Acetyl-5-tetrahydroxybutyl imidazole (THI) is an inhibitor of sphingosine-1-phosphate (S1P) lyase in vivo. THI is not active at S1P lyase in cell-free or cell-based assays but is converted to A6770 in vivo, which is subsequently activated by phosphorylation. In mice, THI (50 µg/ml in drinking water) increases S1P...
Schlagworte: 2-Acetyl-4-tetrahydroxybutyl Imidazole, 2-ATHBI, THI, 1-[5-[(1R,2S,3R)-1,2,3,4-tetrahydroxybutyl]-1H-imidazol-2-yl]-ethanone
Anwendung: S1P lyase inhibitor
CAS 94944-70-4
MW: 230.2 D
ab 86,00 €
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Mouse Sgpl1 / Sphingosine-1-phosphate lyase 1 ELISA Kit
Mouse Sgpl1 / Sphingosine-1-phosphate lyase 1 ELISA Kit

Artikelnummer: G-MOFI00450.96

Anwendung: ELISA
Spezies-Reaktivität: mouse
694,00 €
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4-Deoxypyridoxine Phosphate
4-Deoxypyridoxine Phosphate

Artikelnummer: Cay29973-1

4-Deoxypyridoxine phosphate is a vitamin B6 analog and an inhibitor of sphingosine-1-phosphate (S1P) lyase. It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50s = 100 µM in the absence and presence of...
Schlagworte: 4-Deoxypyridoxine Phosphate, DOP Phosphate, DOP-P, NSC 29870, 5-hydroxy-4,6-dimethyl-3-pyridinemethanol, 3-(dihydrogen...
Anwendung: Vitamin B6 analog, Sphingosine-1-phosphate lyase 1 (S1PL) inhibitor
CAS 883-84-1
MW: 233.2 D
ab 43,00 €
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A6770
A6770

Artikelnummer: Cay29972-1

A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase. It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50 = 6 (EC50 = 98%. Formulation: (Request formulation change), A crystalline solid....
Schlagworte: 1-[5-(hydroxymethyl)-1H-imidazol-2-yl]-ethanone
Anwendung: S1P lyase inhibitor
CAS 1331754-16-5
MW: 140.1 D
ab 109,00 €
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Anti-SGPL1
Anti-SGPL1

Artikelnummer: G-CAB15745.100

WB 1:500 - 1:2000. Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. [The UniProt Consortium]
Schlagworte: Anti-hSPL, Anti-S1PL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 352,00 €
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Anti-SGPL1
Anti-SGPL1

Artikelnummer: ATA-HPA021125.100

Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in...
Schlagworte: Anti-hSPL, Anti-S1PL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate...
Anwendung: WB, IHC, ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 300,00 €
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Anti-SGPL1
Anti-SGPL1

Artikelnummer: ATA-HPA023086.100

Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in...
Schlagworte: Anti-hSPL, Anti-S1PL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 335,00 €
Bewerten
-10 %
Rabattaktion
Human SGPL1 (Sphingosine 1 Phosphate Lyase 1) ELISA Kit
Human SGPL1 (Sphingosine 1 Phosphate Lyase 1) ELISA Kit

Artikelnummer: ELK-ELK9477.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SGPL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SGPL1. Next,...
Schlagworte: S1PL, hSPL, SPL 1, SP-lyase 1, Sphingosine-1-phosphate lyase 1, Sphingosine-1-phosphate aldolase
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
Bewerten
-10 %
Rabattaktion
Anti-SGPL1
Anti-SGPL1

Artikelnummer: ELK-ES13132.100

Protein function: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis (PubMed:11018465, PubMed:14570870, PubMed:24809814, PubMed:28165339). Required for global lipid homeostasis in...
Schlagworte: Anti-S1PL, Anti-hSPL, Anti-SPL 1, Anti-SP-lyase 1, Anti-Sphingosine-1-phosphate lyase 1, Anti-Sphingosine-1-phosphate...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
169,00 € ab 152,10 €
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