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Anti-GCH1 / GTP cyclohydrolase 1
Artikelnummer: NSJ-FY12931
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. GCH1 antibody detects GTP cyclohydrolase 1, the first and rate-limiting enzyme in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for aromatic amino acid hydroxylases and nitric oxide synthases. The UniProt recommended...
| Schlagworte: | Anti-GCH1, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I, GCH1 Antibody / GTP cyclohydrolase 1 |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
7,8-dihydro-L-Biopterin
Artikelnummer: Cay81882-5
BH2 is a precursor of BH4 synthesis. It is a noncompetitive inhibitor of GTP cyclohydrolase I, with a Ki of 14.4 µM.Formal Name: 2-amino-6-(1R,2S-dihydroxypropyl)-7,8-dihydro-4(1H)-pteridinone. CAS Number: 6779-87-9. Synonyms: BH2, Dihydrobiopterin. Molecular Formula: C9H13N5O3. Formula Weight: 239.2. Purity: >97%....
| Schlagworte: | BH2, Dihydrobiopterin, 2-amino-6-(1R,2S-dihydroxypropyl)-7,8-dihydro-4(1H)-pteridinone |
| Anwendung: | GTP cyclohydrolase inhibitor |
| CAS | 6779-87-9 |
| MW: | 239.2 D |
ab 68,00 €
2,4-Diamino-6-hydroxypyrimidine
Artikelnummer: Cay81260-5
2,4-Diamino-6-hydroxypyrimidine (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. In HUVEC cells, the IC50 for inhibition of BH4 biosynthesis is about 0.3 mM. DAHP can be used to effectively block NO production in several cell types.Formal Name:...
| Schlagworte: | DAHP, 2,4-diamino-6(1H)-pyrimidinone |
| Anwendung: | GTP cyclohydrolase I inhibitor |
| CAS | 56-06-4 |
| MW: | 126.1 D |
ab 40,00 €
Anti-GCH1, Internal
Artikelnummer: ARG64624.100
Protein function: Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown. [The...
| Schlagworte: | Anti-GCH1, Anti-DYT5, Anti-GTP-CH-I, EC=3.5.4.16, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-GCH1
Artikelnummer: NSJ-R34104-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: GTP cyclohydrolase 1 Protein function: Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain...
| Schlagworte: | Anti-DYT5, Anti-GCH1, Anti-GTP-CH-I, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I, GCH1 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-GCH1
Artikelnummer: ATA-HPA028612.100
Protein function: Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown. [The...
| Schlagworte: | Anti-GCH1, Anti-DYT5, Anti-GTP-CH-I, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-GCH1
Artikelnummer: CSB-PA929459.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GCH1. Antigen Species: Human
| Schlagworte: | Anti-GCH1, Anti-DYT5, Anti-GTP-CH-I, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I, dystonia 14 antibody, DYT 5... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Anti-GCH1
Artikelnummer: CSB-PA964562.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GCH1. Antigen Species: Human
| Schlagworte: | Anti-GCH1, Anti-DYT5, Anti-GTP-CH-I, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I, dystonia 14 antibody, DYT 5... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
2,4-Diamino-6-hydroxypyrimidine
Artikelnummer: TGM-T7461-100mg
Description: 2,4-Diamino-6-hydroxypyrimidine (DAHP) (DAHP) is a selective, specific inhibitor of GTP cyclohydrolase I, the rate limiting step for de novo pterin synthesis. Target: NO Synthase, Reactive Oxygen Species. Smiles: NC1=NC(N)=CC(=O)N1. References: Sung Y J , Hotchkiss J H , Dieteri R R ....
| Schlagworte: | DAHP |
| Anwendung: | GTP cyclohydrolase I inhibitor |
| CAS | 56-06-4 |
| MW: | 126.12 D |
ab 39,00 €
7,8-Dihydro-L-biopterin
Artikelnummer: TGM-T19160-10mg
Description: 7,8-Dihydro-L-biopterin is an oxidation product of tetrahydrobiopterin. Target: Endogenous Metabolite. Smiles: CC(O)C(O)C1Nc2nc(N)nc(O)c2N=C1
| Anwendung: | GTP cyclohydrolase inhibitor |
| CAS | 6779-87-9 |
| MW: | 239.23 D |
ab 57,00 €
GTP cyclohydrolase 1 (folE), recombinant Escherichia coli
Artikelnummer: CSB-EP009317ENU.1
Organism: Escherichia coli (strain K12 / MC4100 / BW2952). Source: E.coli. Expression Region: 1-222aa. Protein Length: Full Length. Tag Info: C-terminal 6xHis-tagged. Target Protein Sequence: MPSLSKEAAL VHEALVARGL ETPLRPPVHE MDNETRKSLI AGHMTEIMQL LNLDLADDSL METPHRIAKM YVDEIFSGLD YANFPKITLI ENKMKVDEMV TVRDITLTST...
| Schlagworte: | GTP-CH-I, BWG_1935, GTP cyclohydrolase I, GTP cyclohydrolase 1 |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | E.coli |
| MW: | 31.7 kD |
ab 364,00 €
Anti-GCH1
Artikelnummer: ARG45887.50
Protein function: Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown. [The...
| Schlagworte: | Anti-GCH1, Anti-DYT5, Anti-GTP-CH-I, Anti-GTP-CH-I, Anti-GTP cyclohydrolase 1, Anti-GTP cyclohydrolase I, Anti-GTP... |
| Anwendung: | FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
518,00 €