Zu "K01481" wurden 88 Artikel gefunden!
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Cl-Amidine (hydrochloride)
Artikelnummer: Cay10599-1
Cl-Amidine is an irreversible inhibitor of protein arginine deiminases (PADs, IC50s = 0.8, 6.2, and 5.9 µM for PAD1, PAD3, and PAD4, respectively). It is cytotoxic to HL-60, MCF-7, and HT-29 cancer cells (IC50s = 0.25, 0.05, and 1 µM, respectively). Cl-amidine (50 mg/kg) reduces ex vivo extracellular neutrophil...
| Schlagworte: | N-[(1S)-1-(aminocarbonyl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-benzamide, monohydrochloride |
| Anwendung: | Peptidyl arginine deiminase (PAD) inhibitor |
| CAS | 1373232-26-8 |
| MW: | 347.2 D |
ab 66,00 €
Mouse PADI3 (Peptidyl Arginine Deiminase Type III) ELISA Kit
Artikelnummer: ELK-ELK0885.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PADI3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PADI3. Next,...
| Schlagworte: | Pad3, Padi3, Peptidylarginine deiminase III, Protein-arginine deiminase type-3, Protein-arginine deiminase type III |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Mouse PADI6 (Peptidyl Arginine Deiminase Type VI) ELISA Kit
Artikelnummer: ELK-ELK0886.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PADI6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PADI6. Next,...
| Schlagworte: | P75, ePAD, Padi6, Egg and embryo abundant PAD, Peptidylarginine deiminase VI, Arginine deiminase-like protein,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Mouse PADI2 (Peptidyl Arginine Deiminase Type II) ELISA Kit
Artikelnummer: ELK-ELK0888.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PADI2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PADI2. Next,...
| Schlagworte: | Pad2, Padi2, Peptidylarginine deiminase II, Protein-arginine deiminase type-2, Protein-arginine deiminase type II |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Rat PADI2 (Peptidyl Arginine Deiminase Type II) ELISA Kit
Artikelnummer: ELK-ELK0996.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PADI2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PADI2. Next,...
| Schlagworte: | Pad2, Padi2, Peptidylarginine deiminase II, Protein-arginine deiminase type-2, Protein-arginine deiminase type II |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human PADI3 (Peptidyl Arginine Deiminase Type III) ELISA Kit
Artikelnummer: ELK-ELK5090.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PADI3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PADI3. Next,...
| Schlagworte: | PAD3, PADI3, Peptidylarginine deiminase III, Protein-arginine deiminase type-3, Protein-arginine deiminase type III |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Human PADI6 (Peptidyl Arginine Deiminase Type VI) ELISA Kit
Artikelnummer: ELK-ELK3870.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PADI6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PADI6. Next,...
| Schlagworte: | PAD6, PADI6, hPADVI, EC=3.5.3.15, Peptidylarginine deiminase VI, Protein-arginine deiminase type-6, Protein-arginine... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Human PADI2 (Peptidyl Arginine Deiminase Type II) ELISA Kit
Artikelnummer: ELK-ELK4782.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PADI2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PADI2. Next,...
| Schlagworte: | PADI2, PAD-H19, KIAA0994, Peptidylarginine deiminase II, Protein-arginine deiminase type-2, Protein-arginine deiminase... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
GSK484 (hydrochloride)
Artikelnummer: Cay17488-5
GSK484 is a reversible inhibitor of PAD4 (IC50 = 50 nM) that binds to the low-calcium form of the enzyme. It is selective for PAD4 over PAD1-3. GSK484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human...
| Schlagworte: | [(3S,4R)-3-amino-4-hydroxy-1-piperidinyl][2-[1-(cyclopropylmethyl)-1H-indol-2-yl]-7-methoxy-1-methyl-1H-benzimidazol-5-yl]... |
| Anwendung: | Reversible PAD4 inhibitor |
| CAS | 1652591-81-5 |
| MW: | 510 D |
ab 50,00 €
PAD2 (human, recombinant)
Artikelnummer: Cay10785-50
Peptidyl arginine deiminase 2 (PAD2) catalyzes the conversion of arginine residues to citrulline within cellular protein substrates, resulting in the loss of a positive charge, which can alter protein structure and/or function. It is composed of an alpha/beta propeller domain, an IgG1 domain that contains calcium...
| Schlagworte: | PADI2, PAD-H19, PAD-H19, KIAA0994, Peptidylarginine deiminase II, Peptidylarginine deiminase II, Protein-arginine... |
| Anwendung: | Enzyme activity |
642,00 €
Citrulline-specific Probe-rhodamine
Artikelnummer: Cay16172-250
Protein arginine deiminases (PADs) catalyze the posttranslational modification of arginine residues on proteins to form citrulline, which plays a large role in regulating gene expression. Abnormally high PAD activity has been observed in a host of human diseases. Citrulline-specific probe-rhodamine is a highly...
| Schlagworte: | Rh-PG, Rhodamine Phenylglyoxal,... |
| Anwendung: | Fluorescent citrullination detection |
| CAS | 2309313-01-5 |
| MW: | 731.8 D |
ab 238,00 €
GSK106 (hydrochloride)
Artikelnummer: Cay17490-5
Protein arginine deiminase 4 (PAD4) mediates the transformation of protein arginine into citrulline. Citrullination of proteins has normal roles in gene regulation and pathological roles in immunological and inflammatory diseases. GSK106 is an inactive control for the selective PAD4 inhibitors, GSK484 (Cay-17488)...
| Schlagworte: | (3-amino-1-piperidinyl)[2-(1-ethyl-1H-indol-2-yl)-1-methyl-1H-benzimidazol-6-yl]-methanone, monohydrochloride |
| Anwendung: | Inactive PADI4 inhibitor control |
| CAS | 1652591-82-6 |
| MW: | 438 D |
ab 50,00 €