Zu "K01425" wurden 120 Artikel gefunden!
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Anti-Recombinant Glutaminase C, clone 8D10
Artikelnummer: E-AN301062L.100
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism,...
| Schlagworte: | Anti-GLS, Anti-K-glutaminase, Anti-L-glutamine amidohydrolase, Anti-Glutaminase kidney isoform, mitochondrial, Recombinant... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 257,00 €
Anti-Glutaminase / GLS
Artikelnummer: NSJ-F54260-0.05ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a...
| Schlagworte: | Anti-GLS, Anti-K-glutaminase, Anti-L-glutamine amidohydrolase, Anti-Glutaminase kidney isoform, mitochondrial, Glutaminase... |
| Anwendung: | WB, IHC (paraffin), FC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 361,00 €
CB-839
Artikelnummer: Cay22038-5
CB-839 is an orally bioavailable noncompetitive inhibitor of the glutaminase 1 (GLS1) splice variants, kidney-type (KGA) and glutaminase C (GAC), which convert glutamine into glutamate. CB-839 inhibits human recombinant GAC with IC50 values of less than 50 nM, varying based on the length of preincubation. It...
| Schlagworte: | GLS1 Inhibitor III,... |
| Anwendung: | Glutaminase inhibitor |
| CAS | 1439399-58-2 |
| MW: | 571.6 D |
ab 91,00 €
BPTES
Artikelnummer: Cay19284-1
BPTES is an allosteric inhibitor of kidney-type glutaminase 1 (GLS1, IC50 = 3.3 µM) that drives the formation of inactive GLS1 tetramers. It is selective for GLS1 over GLS2, glutamate dehydrogenase, and gamma-glutamyl transpeptidase. BPTES decreases glutaminase activity and reduces proliferation of aerobic P493...
| Schlagworte: | N,N'-[thiobis(2,1-ethanediyl-1,3,4-thiadiazole-5,2-diyl)]bis-benzeneacetamide |
| Anwendung: | GLS inhibitor |
| CAS | 314045-39-1 |
| MW: | 524.7 D |
ab 40,00 €
Glutaminase Inhibitor Compound 968
Artikelnummer: Cay17199-5
Glutaminase inhibitor compound 968 is a cell-permeable, reversible inhibitor of a mitochondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 µM), which is commonly found in cancer cells. Through this action, glutaminase inhibitor compound 968 blocks transformation induced by Rho GTPases and inhibits the...
| Schlagworte: | 5-[3-bromo-4-(dimethylamino)phenyl]-2,3,5,6-tetrahydro-2,2-dimethyl-benzo[a]phenanthridin-4(1H)-one |
| Anwendung: | Glutaminase inhibitor |
| CAS | 311795-38-7 |
| MW: | 475.4 D |
ab 51,00 €
Glutaminase Assay Kit (Colorimetric)
Artikelnummer: ARG82767.96
This Glutaminase Assay Kit (Colorimetric) is a detection kit for the quantification of Glutaminase activity in cells, bacteria and tissue samples. Protein function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates...
| Schlagworte: | GLS, GLS1 |
| Anwendung: | FA |
| Spezies-Reaktivität: | broad |
863,00 €
BPTES
Artikelnummer: AG-CR1-3690-M005
Selective, allosteric non-competitive inhibitor of glutaminase 1 (GLS1), selective for GLS1 over GLS2, glutamate dehydrogenase, and gamma-glutamyl transpeptidase, consequently inhibiting glutaminolysis. Useful agent for immunometabolism research. Glutaminase converts glutamine to glutamate, which is an important...
| Schlagworte: | Bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl)ethyl sulfide |
| Anwendung: | Selective, allosteric non-competitive glutaminase 1 (GLS1) inhibitor |
| CAS | 314045-39-1 |
| MW: | 524.7 D |
ab 33,00 €
Glutaminase (GLS) Activity Assay Kit
Artikelnummer: E-BC-K660-M.96
Detection instrument: Microplate reader. Detection principle: Glutamine is decomposed to produce glutamic acid under the action of glutaminase. Glutamic acid is further transformed by glutamic acid dehydrogenase. Meanwhile, NAD+ is reduced to NADH, Which under the action of hydrogen transmitter, transfer electrons...
| Schlagworte: | GLS, GLS1 |
324,00 €
Human GLS / Glutaminase kidney isoform, mitochondrial...
Artikelnummer: G-HUFI01447.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Glutaminase (EC 3.5.1.2), Escherichia coli
Artikelnummer: NZY-AE00071
Glutaminase (EC 3.5.1.2) is purified from a recombinant E. coli strain. Glutaminase is an amidohydrolase enzyme which generates glutamate from glutamine. Glutaminase has tissue-specific isoenzymes. Importantly, glutaminase is found in glial cells. Glutaminase is expressed in periportal hepatocytes, where it...
| Schlagworte: | ybaS, b0485, Glutaminase 1 |
| Anwendung: | Enzyme assays |
199,00 €
IPN60090
Artikelnummer: Cay35855-1
IPN60090 is an inhibitor of glutaminase 1 (GLS1, IC50 = 0.031 µM for the glutaminase C isoform). It is selective for GLS1 over GLS2 (IC50 = >50 µM), as well as panels of 80 ion channels and receptors and 97 kinases at 10 µM. IPN60090 also binds to zinc finger SWIM domain-containing protein 4 (ZSWIM4, Kd = 2.98 µM)....
| Schlagworte: | IACS-6274,... |
| Anwendung: | GLS1 inhibitor |
| CAS | 1853164-83-6 |
| MW: | 532.5 D |
ab 274,00 €
Anti-Glutaminase
Artikelnummer: ARG55696.100
Protein function: Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. [The UniProt Consortium]
| Schlagworte: | Anti-GLS, Anti-GLS1, EC=3.5.1.2, Anti-K-glutaminase, Anti-L-glutamine amidohydrolase, Anti-Glutaminase kidney isoform,... |
| Anwendung: | WB, IHC (paraffin), ICC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
616,00 €