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Zu "K01413" wurden 76 Artikel gefunden!
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Artikelnummer: TGM-T83168-100mg
Description: Aderamastat (FP-025) is an orally active matrix metalloproteinase 12 (MMP-12) inhibitor used for research in allergic asthma, COPD, and pulmonary fibrosis. Target: MMP. Smiles: O=C1NC(=O)C(N1)C=2OC=CC2SC3=CC=C(OCC=4C=CC=C(C4)C)C=C3. References: Li, Yuhua, et al. Safe administration of MMP-12 inhibitor....
Schlagworte: | FP-025, FP-003 |
Anwendung: | Targets matrix metalloproteinase-12 (macrophage elastase) [EC:3.4.24.65] (MMP12) |
CAS | 877176-23-3 |
MW: | 394.44 D |
ab 100,00 €
Artikelnummer: TGM-TMPJ-00942-10ug
Description: Matrix metalloproteinase-12(MMP12) is a secreted protein.It contains 4 hemopexin repeats and belongs to the peptidase M10A family. MMP12 may be involved in tissue injury and remodeling and have significant elastolytic activity. It can accept large and small amino acids at the P1' site, but has a...
Schlagworte: | Matrix metalloproteinase-12, Macrophage metalloelastase, Mmp12, MMP-12, Mme, Mmel |
MW: | 64 kD |
ab 181,00 €
Artikelnummer: TGM-TMPH-01633-100ug
Description: May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying...
Schlagworte: | Macrophage elastase, Matrix metalloproteinase-12, Macrophage metalloelastase, MMP12 |
MW: | 46.1 kD |
ab 198,00 €
Artikelnummer: TGM-TMPY-02869-100ug
Description: Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological...
Schlagworte: | HME, ME, MME, matrix metallopeptidase 12, MMP-12 |
MW: | 18.2 kD |
ab 190,00 €
Artikelnummer: TGM-T40080-2mg
Description: (±)-Taxifolin ((±)-Dihydroquercetin) is the racemate of Taxifolin, a flavonoid with anti-tyrosinase and anti-fibrotic activity, commonly found in onion, silymarin, French maritime pine bark, and Douglas fir bark. It inhibits collagenase with an IC50 value of 193.3 µM and acts as a free radical scavenger...
Schlagworte: | (±)-Dihydroquercetin |
Anwendung: | Dihyroflavonol, lipid synthesis regulator, MMP12 inhibitor |
CAS | 24198-97-8 |
MW: | 304.25 D |
30,00 €
Artikelnummer: TGM-T60083-100mg
Description: MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12. Target: MMP. Smiles: N(C(OC)=O)C=1C=C2C=3C(OC2=CC1)=CC(S(N[C@H](C(C)C)C(O)=O)(=O)=O)=CC3. References: Wei Li, et al. A Selective Matrix Metalloprotease 12 Inhibitor for...
Schlagworte: | MMP12, MMP408 |
Anwendung: | MMP12 inhibitor |
CAS | 1258003-93-8 |
MW: | 420.44 D |
ab 194,00 €
Artikelnummer: CSB-PA004869.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-ME, Anti-HME, Anti-MME, Anti-hME, Anti-MMP12, Anti-MMP-12, EC=3.4.24.65, Anti-Macrophage elastase, Anti-Macrophage... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Artikelnummer: CSB-PA000049.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-ME, Anti-HME, Anti-MME, Anti-hME, Anti-MMP12, Anti-MMP-12, EC=3.4.24.65, Anti-Macrophage elastase, Anti-Macrophage... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 126,00 €
Artikelnummer: CSB-PA12379A0Rb.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MMP12. Antigen Species: Human
Schlagworte: | Anti-ME, Anti-HME, Anti-MME, Anti-hME, Anti-MMP12, Anti-MMP-12, EC=3.4.24.65, Anti-Macrophage elastase, Anti-Macrophage... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Artikelnummer: CSB-PA984456.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: MMP12. Antigen Species: Human
Schlagworte: | Anti-ME, Anti-HME, Anti-MME, Anti-hME, Anti-MMP12, Anti-MMP-12, EC=3.4.24.65, Anti-Macrophage elastase, Anti-Macrophage... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 167,00 €
Artikelnummer: CSB-EP014659HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 106-470aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: GPVWRKHYIT YRINNYTPDM NREDVDYAIR KAFQVWSNVT PLKFSKINTG MADILVVFAR GAHGDFHAFD GKGGILAHAF GPGSGIGGDA HFDEDEFWTT HSGGTNLFLT AVHEIGHSLG...
Schlagworte: | ME, HME, hME, MME, MMP12, MMP-12, EC=3.4.24.65, Macrophage elastase, Macrophage metalloelastase, Matrix... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 46.1 kD |
ab 219,00 €
Artikelnummer: Cay18647-500
(±)-Taxifolin is a flavonoid that has been found in M. butyracea and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) radicals in cell-free assays. (±)-Taxifolin is cytotoxic to HCT116 cells (IC50 = 63.42 µM). It inhibits HMG-CoA reductase activity and cholesterol...
Schlagworte: | (±)-Dihydroquercetin, (2R,3R)-rel-2-(3,4-dihydroxyphenyl)-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
Anwendung: | Dihyroflavonol, lipid synthesis regulator, MMP12 inhibitor |
CAS | 24198-97-8 |
MW: | 304.3 D |
ab 78,00 €