Zu "K01380" wurden 134 Artikel gefunden!
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Renin (human, recombinant)
Artikelnummer: Cay10006217-25
Renin is an aspartyl protease glycoprotein, a member of the aspartic acid protease family, and a hormone. It is a single-chain polypeptide in which the N- and C-terminal portions contain an aspartate residue responsible for its catalytic activity. It is formed from prorenin, a zymogen found primarily in the...
| Schlagworte: | REN, Renin, Renin, Angiotensinogenase, Angiotensinogenase |
| Anwendung: | Enzyme activity, WB |
570,00 €
Prorenin (human, recombinant)
Artikelnummer: Cay10007599-100
Prorenin is the inactive precursor of renin, which is a key enzyme in the regulation of blood pressure and electrolyte balance. In renal juxtaglomerular cells, sequential cleavage of the N-terminal 20 and 46 amino acids of preprorenin produces prorenin and active renin, respectively. Renin catalyzes the conversion...
| Schlagworte: | REN, Renin, Renin, Angiotensinogenase, Angiotensinogenase |
| Anwendung: | Protease assay |
541,00 €
Pepstatin A
Artikelnummer: Cay9000469-5
Pepstatin A is a bacteria-derived pentapeptide inhibitor of aspartic proteases. It inhibits pepsin, cathepsin D, and HIV protease (IC50s = 50s = 0.32 and 15 µM for the porcine and human enzymes, respectively). It inhibits HIV replication in infected H9 cells when used at a concentration of 100 µM and inhibits...
| Schlagworte: | NSC 272671, Pepsin Inhibitor S 735A,... |
| Anwendung: | Aspartic protease inhibitor |
| CAS | 26305-03-3 |
| MW: | 685.9 D |
ab 45,00 €
Renin 1 (rat), recombinant protein (His Tag)
Artikelnummer: E-PDMR100045.1
Protein function: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. [The UniProt Consortium]
| Schlagworte: | Ren, Ren1, Renin, Angiotensinogenase, Recombinant Rat Renin 1 Protein(His Tag) |
| Exprimiert in: | Mammalian |
| Ursprungsart: | rat |
ab 192,00 €
Renin, rat recombinant protein, His-tag
Artikelnummer: BPS-80201
Rat, activated renin (GenBank Accession No. NM_012642), amino acids 65 ? 402 (end) with C-terminal HIS tag, MW=38.5 kDa, expressed in a HEK293 cell expression system.
| Schlagworte: | Ren, Ren1, Renin, Angiotensinogenase, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | Human cells |
| Ursprungsart: | rat |
| MW: | 38.5 kD |
655,00 €
Renin Fluorogenic Substrate
Artikelnummer: Cay10006906-1
The renin fluorogenic substrate consists of the normal peptide substrate for renin which has been linked to the fluorophore EDANS at one end and to a non-fluorescent quenching molecule (Dabcyl) at the other. After cleavage by renin, the product (peptide-EDANS) is brightly fluorescent and can be easily analyzed using...
| Schlagworte: | Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(Dabcyl)-Arg-OH |
| Anwendung: | Renin assays |
| CAS | 791068-69-4 |
| MW: | 2282.7 D |
453,00 €
Aliskiren (hemifumarate)
Artikelnummer: Cay19640-10
Aliskiren is a nonpeptide inhibitor of renin (IC50 = 0.6 nM for the human enzyme). Aliskiren (10 and 30 mg/kg per day) reduces blood pressure and prevents albuminuria in renin-overexpressing TG(mRen-2)27 rats in a model of streptozotocin-induced diabetes. It also reduces cardiac hypertrophy and fibrosis induced by...
| Schlagworte: | CGP 60536, SPP 100,... |
| Anwendung: | Renin inhibitor |
| CAS | 173334-58-2 |
| MW: | 609.8 D |
ab 49,00 €
Amplite(TM) Fluorimetric Renin Assay Kit *Red Fluorescence*
Artikelnummer: ABD-13530
Renin is an enzyme that participates in the body's renin-angiotensin system (RAS) that mediates extracellular volume and arterial vasoconstriction. It regulates blood pressure and electrolyte homoeostasis. Angiotensin II constricts blood vessels leading to increased blood pressure. It also increases the secretion of...
| Schlagworte: | EC=3.4.23.15, Angiotensinogenase |
| Anwendung: | Enzyme kinetics, Inhibitor screening, HTS |
291,00 €
Activated Renin, human recombinant protein
Artikelnummer: BPS-80200
Human Activated Renin (GenBank Accession No. NM_000537), amino acids 24 ? 406 (end) with C-terminal HIS tag, MW=43.7 kDa, expressed in a mammalian expression system.
| Schlagworte: | REN, Renin, Angiotensinogenase, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| MW: | 43.7 kD |
685,00 €
Human Plasma Renin Activity (PRA) ELISA Kit
Artikelnummer: ARG80882.96
Protein function: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. [The UniProt Consortium]
| Schlagworte: | Anti-REN, Anti-Renin, EC=3.4.23.15, Anti-Angiotensinogenase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.241,00 €
Aliskiren Hydrochloride
Artikelnummer: BPS-27300
Aliskiren Hydrochloride is an orally active, synthetic nonpeptide Renin inhibitor that has been shown to work as an antihypertensive.
| Anwendung: | Renin inhibitor |
| MW: | 588.2 D |
1.207,00 €
Renin Assay Kit
Artikelnummer: BPS-80211
Renin is a protease that is synthesized by the kidneys. Renin catalyzes the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the treatment of hypertension (high blood pressure). The Renin Assay...
| Schlagworte: | Angiotensinogenase, |
| Anwendung: | Renin assays |
1.687,00 €