Zu "K01370" wurden 147 Artikel gefunden!
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Anti-Caspase-1 (p20) (mouse), clone Casper-1
Artikelnummer: AG-20B-0042-C100
Recognizes endogenous full-length and activated (p20 fragment) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
| Anwendung: | WB, IHC, IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | mouse |
462,00 €
Anti-Caspase-1 (p20) (human), clone Bally-1
Artikelnummer: AG-20B-0048-C100
Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
462,00 €
FLICA(TM) 660 Caspase-1 Assay Kit (25-50 tests)
Artikelnummer: ICT-9122
Kit includes 660-YVAD-FMK red caspase-1 probe, 10x Apoptosis Wash Buffer, Fixative, Technical Protocol. The red FLICA® 660-YVAD-FMK caspase-1 detection probe is comprised of the preferred affinity peptide sequence for active caspase-1 (YVAD), a far-red fluorescent 660 dye label, and a fluoromethyl ketone (FMK)...
| Anwendung: | FM, FC |
389,00 €
FAM-FLICA(R) Caspase 1 Assay Kit
Artikelnummer: ICT-98
This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC |
982,00 €
FAM-FLICA(R) Caspase 1 Assay Kit
Artikelnummer: ICT-97
This kits makes use of a cell-permeant green fluorecent probe (FAM-YVAD-FMK) that binds to active caspase-1 in living cells undergoing apoptosis. Excitation wavelength 488-492nm, emission 515-535nm.
| Anwendung: | FM, FC |
353,00 €
Anti-Recombinant Caspase-1, clone 6H5
Artikelnummer: E-AN300732L.100
CASP1(caspase 1) Homo sapiens This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved...
| Schlagworte: | Anti-p45, Anti-CASP1, Anti-Caspase-1, Anti-Interleukin-1 beta convertase, Anti-Interleukin-1 beta-converting enzyme,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Caspase-1 (mouse) ELISA Kit
Artikelnummer: AG-45B-0002-KI01
Detection Type: Colorimetric. Assay Type: Sandwich 96 well assay. Sample Type: Cell Culture Supernatant. Range: 0.15ng/ml to 10ng/ml. Sensitivity: 33pg/ml. Detects mouse caspase-1 (proform as well as p10 and p20 domain). Does not detect human caspase-1. Caspase-1 is the best-described inflammatory caspase. It...
| Schlagworte: | Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
660,00 €
Emricasan
Artikelnummer: Cay22204-5
Emricasan is a pan-caspase inhibitor. Ex vivo, emricasan (10 mg/kg) prevents cold ischemia-warm reperfusion-induced sinusoidal endothelial cell (SEC) apoptosis and inhibits caspase-3 activation in rat liver by 55 and 94%, respectively. In vivo, emricasan reduces alanine aminotransferase (ALT) levels (ED50s = 95%....
| Schlagworte: | IDN-6556, PF-03491390,... |
| Anwendung: | Antiinflammatory, Caspase-1 inhibitor |
| CAS | 254750-02-2 |
| MW: | 569.5 D |
ab 42,00 €
Pyroptosis/Caspase-1 Assay, Far Red
Artikelnummer: ICT-9158
ICT's Pyroptosis/Caspase-1 Assay, Far Red utilizes our popular FLICA technology to measure caspase-1 activation. Using this kit, researchers can easily detect pyroptotic cells in their whole cell samples in vitro. This complete kit includes Nigericin for the simple and reliable generation of a positive control....
| Schlagworte: | IL1BC, CASP1, EC=3.4.22.36 |
| Anwendung: | FC, fluorescence microscopy, CASP1 activation detection |
563,00 €
5-FAM-YVAD-FMK
Artikelnummer: ABD-13483
Molecular weight: 854.84. Excitation (nm): 493. Emission (nm): 517. Extinction coefficient (cm-1 M-1): 83000. Correction factor (280 nm): 0.178. Correction factor (260 nm): 0.32. FAM-YVAD-FMK, i.e., 5-carboxyfluorescein-Tyr-Val-Ala-Asp-fluoromethylketone, binds irreversibly to active caspase 1 in stimulated cells....
| Anwendung: | FM, FC, fluorescent microplate reader, active caspase-1 detection |
| MW: | 854.84 D |
277,00 €
Anti-Caspase-1 (p20) (human) , clone Bally-1, Biotin...
Artikelnummer: AG-20B-0048B-C100
Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1...
| Schlagworte: | Interleukin-1 beta Convertase, IL-1BC, Interleukin-1 beta-converting Enzyme, ICE |
| Anwendung: | WB |
| Wirt: | mouse |
| Spezies-Reaktivität: | human |
506,00 €
Ac-YVAD-CHO
Artikelnummer: Cay10016-1
Ac-YVAD-CHO is an inhibitor of caspase-1/interleukin-1beta converting enzyme (ICE, Ki = 0.76 nM) and an acetylated form of the caspase-1 inhibitor YVAD-CHO (Cay-27420). It is selective for caspase-1 over caspase-4, -5, -8, -9, and -10 (Kis = 163-970 nM), as well as over caspase-2, -3, -6, and -7 (Kis = >10,000 nM...
| Schlagworte: | N-Ac-Tyr-Val-Ala-Asp-CHO, N-acetyl-L-tyrosyl-L-valyl-N-[(1S)-2-carboxyl-1-formylethyl]-L-alaninamide |
| Anwendung: | Caspase-1 inhibitor |
| CAS | 143313-51-3 |
| MW: | 492.5 D |
ab 97,00 €