Zu "K01365" wurden 101 Artikel gefunden!
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Magic Red(TM) Cathepsin L Assay Kit
Artikelnummer: ICT-941
This kit is based on a cell-permeant fluorescent probe (MR-(FR)2) designed for real-time detection of cathepsin L activity within whole living cells, using a fluorescence microscope. Excitation wavelength 560nm, emission 610-650nm.
| Anwendung: | Real time FM, FC |
311,00 €
Cathepsin L, Human
Artikelnummer: GSC-Z03591-1
Cathepsin L is an enzyme. Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins...
| Schlagworte: | CTSL, Cathepsin L1, Procathepsin L, Major excreted protein |
| Ursprungsart: | human |
ab 128,00 €
Cathepsin Inhibitor 1
Artikelnummer: Cay28790-1
Cathepsin inhibitor 1 is an inhibitor of cathepsin L (IC50 = 12. nM). It is selective for cathepsin L over cathepsin L2, cathepsin S, cathepsin K, and cathepsin B (IC50s = 199. 1,000, 3,162. and 6,309. nM, respectively).. Solulibility: DMSO: Soluble: = 10 mg/ml: Ethanol: Soluble: = 10 mg/ml.
| Schlagworte: | N-[(1S)-1-[(3-chlorophenyl)methyl]-2-[(cyanomethyl)amino]-2-oxoethyl]-3-(1,1-dimethylethyl)-1-methyl-1H-pyrazole-5-carboxa... |
| Anwendung: | Cathepsin L inhibitor |
| CAS | 225120-65-0 |
| MW: | 401.88976 D |
ab 38,00 €
![K777 [K11777]](https://www.biomol.com/media/image/e7/bc/7c/AG-CR1-0158-M001_200x200.png "K777 [K11777]")
K777 [K11777]
Artikelnummer: AG-CR1-0158-M005
Solid. Soluble in DMSO. Insoluble in water. Potent, irreversible cysteine protease inhibitor, Broad-range cathepsin inhibitor (for all known cathepsins) useful for inflammasome inhibition. Inhibits cathepsins B, L, S, C, V, K and papain in cell-free assays. Inhibits cathepsin X as well, Suppresses particle-induced...
| Schlagworte: | K-777, K-11777, N-Pip-F-hF-VS Phenyl, N-Pip-phenylalanine-homophenylalanine-vinyl sulfone phenyl,... |
| Anwendung: | Potent irreversible cysteine protease inhibitor |
| CAS | 233277-99-1 |
| MW: | 574,7 D |
ab 55,00 €
Magic Red(TM) Cathepsin L Assay Kit
Artikelnummer: ICT-942
This kit is based on a cell-permeant fluorescent probe (MR-(FR)2) designed for real-time detection of cathepsin L activity within whole living cells, using a fluorescence microscope. Excitation wavelength 560nm, emission 610-650nm.
| Anwendung: | Real time FM, FC |
822,00 €
Cathepsin L Inhibitor
Artikelnummer: Cay23249-1
Cathepsin L inhibitor is a potent inhibitor of cathepsin L (IC50 = 0.85 nM). It is selective for cathepsin L over calpain II and cathepsin B (IC50s = 184, and 85.1 nM, respectively). It is trypanocidal with an ED50 value of 45 nM against T. brucei that is well below the ED50 value of 21,500 nM for human HL-60 cells....
| Schlagworte: | SB 412515, N-[(1S)-2-[[(1S)-1-formyl-2-(4-hydroxyphenyl)ethyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-carbamic acid,... |
| Anwendung: | CTSL inhibitor |
| CAS | 167498-29-5 |
| MW: | 446.5 D |
ab 44,00 €
COVID-19 Forschung
E64
Artikelnummer: LKT-E0001.5
E64 is an inhibitor of cysteine proteases. E64 decreases production of IL-8 in vitro.
| Anwendung: | Cysteine protease inhibitor |
| CAS | 66701-25-5 |
| MW: | 357.41 D |
ab 190,00 €
COVID-19 Forschung
E-64
Artikelnummer: Cay10007963-25
E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities. It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the...
| Schlagworte: | (2S,3S)-3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic... |
| Anwendung: | Cysteine protease inhibitor |
| CAS | 66701-25-5 |
| MW: | 357.4 D |
ab 81,00 €
CA-074 methyl ester
Artikelnummer: Cay18469-5
CA-074 methyl ester is a cell-permeable inhibitor of cathepsin B and L in vivo and in whole cells. The methyl ester is hydrolyzed by intracellular esterases releasing the active inhibitor, CA-074. This compound has primarily been used to study the role of cathepsin B in neurodegeneration, cancer cell metastasis,...
| Schlagworte: | N-[[(2S,3S)-3-[(propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline, methyl ester |
| Anwendung: | Cell-permeable cathepsin B / L inhibitor |
| CAS | 147859-80-1 |
| MW: | 397.5 D |
ab 93,00 €
Z-Phe-Arg-AFC
Artikelnummer: AG-CP3-0028-M005
Fluorogenic substrate, specifically used to determine the enzyme activity of Cathepsin L. Useful for the study of cathepsin activity and for screening small molecule inhibitors for drug discovery and HTS applications. Likely to be cleaved by cathepsins B, F, K, S and L, cathepsins L-like proteases and proteases such...
| Schlagworte: | Z-FR-AFC . TFA |
| Anwendung: | Cathepsin L substrate |
| CAS | 65147-22-0 |
ab 83,00 €
Z-FR-AMC (trifluoroacetate salt)
Artikelnummer: Cay34045-10
Z-FR-AMC is a fluorogenic substrate for cathepsin L. Upon enzymatic cleavage by cathepsin L, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin L activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.Formal Name:...
| Schlagworte: | Z-FR-7-amino-4-Methylcoumarin, Z-Phe-Arg-AMC,... |
| Anwendung: | Fluorogenic cathepsin L substrate |
| MW: | 612.7 D |
ab 93,00 €
Cathepsin L Inhibitor Screening Assay Kit
Artikelnummer: BPS-79591-1
The Cathepsin L Inhibitor Screening Assay Kit is designed to measure the protease activity of Cathepsin L for screening and profiling applications. The Cathepsin L assay kit comes in a convenient 96-well format, with purified Cathepsin L, its fluorogenic substrate, and Cathepsin buffer for 100 enzyme reactions. In...
| Schlagworte: | CTSL1, |
| Anwendung: | Enzyme kinetics, drug discovery, HTS |
| Spezies-Reaktivität: | human |
ab 849,00 €