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Zu "K01363" wurden 138 Artikel gefunden!
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Artikelnummer: ICT-937
This kit is based on a cell-permeant fluorescent probe (MR-(RR)2) designed for real-time detection of cathepsin B activity within whole living cells, using a fluorescence microscope. Excitation wavelength 560nm, emission 610-650nm.
| Anwendung: | Real time FM, FC |
311,00 €
Artikelnummer: E-AN006970L.100
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This protease has been implicated in pathological conditions, e.g., tumor progression and arthritis. In...
| Schlagworte: | Anti-Ctsb, Anti-Cathepsin B, Anti-Cathepsin B1, CTSB Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 110,00 €
Artikelnummer: ICT-938
This kit is based on a cell-permeant fluorescent probe (MR-(RR)2) designed for real-time detection of cathepsin B activity within whole living cells, using a fluorescence microscope. Excitation wavelength 560nm, emission 610-650nm.
| Anwendung: | Real time FM, FC |
822,00 €
Artikelnummer: ARG81703.96
Protein function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Has also been implicated in tumor invasion and metastasis. [The UniProt Consortium]
| Schlagworte: | Ctsb |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.085,00 €
Artikelnummer: GSC-Z03322-10
Cathepsin B is an enzymatic protein that is a member of the peptidase (or protease) family. Elevated lev- els of cathepsin B occur in a wide variety of disease,causing numerous pathologies including cell death, inflammation, and the production of toxic peptides. For example, neuroscience research suggests that...
| Schlagworte: | CTSB, Cathepsin B, Cathepsin B1, APP secretase |
| Exprimiert in: | Hamster cells |
| Ursprungsart: | human |
222,00 €
Artikelnummer: GSC-Z03577-1
Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least...
| Schlagworte: | CTSB, Cathepsin B, Cathepsin B1, APP secretase |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
ab 1.216,00 €
Artikelnummer: E-PDMH100165.1
Protein function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (PubMed:12220505). Cleaves matrix extracellular phosphoglycoprotein MEPE (PubMed:12220505). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also...
| Schlagworte: | CPSB, CTSB, Recombinant Human Cathepsin B Protein(His Tag) |
| Exprimiert in: | Mammalian |
| Ursprungsart: | human |
ab 192,00 €
Artikelnummer: Cay18469-1
CA-074 methyl ester is a cell-permeable inhibitor of cathepsin B and L in vivo and in whole cells. The methyl ester is hydrolyzed by intracellular esterases releasing the active inhibitor, CA-074. This compound has primarily been used to study the role of cathepsin B in neurodegeneration, cancer cell metastasis,...
| Schlagworte: | N-[[(2S,3S)-3-[(propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline, methyl ester |
| Anwendung: | Cell-permeable cathepsin B / L inhibitor |
| CAS | 147859-80-1 |
| MW: | 397.5 D |
ab 93,00 €
Artikelnummer: AG-CP3-7002-M005
White to off-white solid. Soluble in water, ethanol, methanol, DMSO or acetonitrile. Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D, Similar activity spectrum comparable to leupeptin...
| Schlagworte: | [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl |
| Anwendung: | Papain / trypsin / trypsin-like serine protease / cathepsin A & B & D inhibitor |
| CAS | 37682-72-7 |
| MW: | 677,6 D |
ab 44,00 €
Artikelnummer: Cay42444-1
Z-FA-FMK is an inhibitor of cathepsin B (Ki = 1. µM). It also is an inhibitor of caspase-2, -3, -6, -7, and -9 (IC50 = 6. 15. 32. 9. and 110. µM, respectively). Z-FA-FMK inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), in a cell-free...
| Schlagworte: | Cathepsin B Inhibitor, Z-Phe-Ala-Fluoromethyl Ketone,... |
| Anwendung: | Cathepsin B inhibitor |
| CAS | 96922-64-4 |
| MW: | 386.42 D |
186,00 €
Artikelnummer: E-AB-10208.120
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP)....
| Schlagworte: | Anti-CPSB, Anti-CTSB, EC=3.4.22.1, CTSB Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: AG-CR1-0158-M001
Solid. Soluble in DMSO. Insoluble in water. Potent, irreversible cysteine protease inhibitor, Broad-range cathepsin inhibitor (for all known cathepsins) useful for inflammasome inhibition. Inhibits cathepsins B, L, S, C, V, K and papain in cell-free assays. Inhibits cathepsin X as well, Suppresses particle-induced...
| Schlagworte: | K-777, K-11777, N-Pip-F-hF-VS Phenyl, N-Pip-phenylalanine-homophenylalanine-vinyl sulfone phenyl,... |
| Anwendung: | Potent irreversible cysteine protease inhibitor |
| CAS | 233277-99-1 |
| MW: | 574,7 D |
ab 55,00 €