Zu "K01363" wurden 152 Artikel gefunden!
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Magic Red(TM) Cathepsin B Assay Kit
Artikelnummer: ICT-937
This kit is based on a cell-permeant fluorescent probe (MR-(RR)2) designed for real-time detection of cathepsin B activity within whole living cells, using a fluorescence microscope. Excitation wavelength 560nm, emission 610-650nm.
| Anwendung: | Real time FM, FC |
311,00 €
Anti-CTSB
Artikelnummer: E-AN006970L.100
Cathepsin B is a papain-family cysteine protease that is normally located in lysosomes, where it is involved in the turnover of proteins and plays various roles in maintaining the normal metabolism of cells. This protease has been implicated in pathological conditions, e.g., tumor progression and arthritis. In...
| Schlagworte: | Anti-Ctsb, Anti-Cathepsin B, Anti-Cathepsin B1, CTSB Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 110,00 €
Magic Red(TM) Cathepsin B Assay Kit
Artikelnummer: ICT-938
This kit is based on a cell-permeant fluorescent probe (MR-(RR)2) designed for real-time detection of cathepsin B activity within whole living cells, using a fluorescence microscope. Excitation wavelength 560nm, emission 610-650nm.
| Anwendung: | Real time FM, FC |
822,00 €
Mouse Cathepsin B ELISA Kit
Artikelnummer: ARG81703.96
Protein function: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Has also been implicated in tumor invasion and metastasis. [The UniProt Consortium]
| Schlagworte: | Ctsb |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.085,00 €
CA-074 methyl ester
Artikelnummer: Cay18469-1
CA-074 methyl ester is a cell-permeable inhibitor of cathepsin B and L in vivo and in whole cells. The methyl ester is hydrolyzed by intracellular esterases releasing the active inhibitor, CA-074. This compound has primarily been used to study the role of cathepsin B in neurodegeneration, cancer cell metastasis,...
| Schlagworte: | N-[[(2S,3S)-3-[(propylamino)carbonyl]-2-oxiranyl]carbonyl]-L-isoleucyl-L-proline, methyl ester |
| Anwendung: | Cell-permeable cathepsin B / L inhibitor |
| CAS | 147859-80-1 |
| MW: | 397.5 D |
ab 97,00 €
Antipain . dihydrochloride
Artikelnummer: AG-CP3-7002-M005
White to off-white solid. Soluble in water, ethanol, methanol, DMSO or acetonitrile. Potent reversible inhibitor of serine/cysteine proteases and some trypsin-like proteases. Inhibits papain, trypsin and trypsin-like serine proteases as well as cathepsin A, B and D, Similar activity spectrum comparable to leupeptin...
| Schlagworte: | [(S)-1-Carboxy-2-phenylethyl]-carbamoyl-Arg-Val-arginal . 2HCl |
| Anwendung: | Papain / trypsin / trypsin-like serine protease / cathepsin A & B & D inhibitor |
| CAS | 37682-72-7 |
| MW: | 677,6 D |
ab 44,00 €
Anti-CTSB
Artikelnummer: E-AB-10208.120
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP)....
| Schlagworte: | Anti-CPSB, Anti-CTSB, EC=3.4.22.1, CTSB Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
![K777 [K11777]](https://www.biomol.com/media/image/e7/bc/7c/AG-CR1-0158-M001_200x200.png "K777 [K11777]")
K777 [K11777]
Artikelnummer: AG-CR1-0158-M001
Solid. Soluble in DMSO. Insoluble in water. Potent, irreversible cysteine protease inhibitor, Broad-range cathepsin inhibitor (for all known cathepsins) useful for inflammasome inhibition. Inhibits cathepsins B, L, S, C, V, K and papain in cell-free assays. Inhibits cathepsin X as well, Suppresses particle-induced...
| Schlagworte: | K-777, K-11777, N-Pip-F-hF-VS Phenyl, N-Pip-phenylalanine-homophenylalanine-vinyl sulfone phenyl,... |
| Anwendung: | Potent irreversible cysteine protease inhibitor |
| CAS | 233277-99-1 |
| MW: | 574,7 D |
ab 55,00 €
Leupeptin (hemisulfate)
Artikelnummer: Cay14026-10
Leupeptin is a reversible inhibitor of cysteine, serine, and threonine proteases that is produced naturally by Streptomyces. It has been reported to inhibit cathepsin B (Ki = 6 nM), calpain (Ki = 10 nM), trypsin (Ki = 35 nM), plasmin (Ki = 3.4 µM), and kallikrein (Ki = 19 µM), and has no effect against chymotrypsin,...
| Schlagworte: | Acetyl-L-leucyl-L-leucyl-L-argininal, N-acetyl-L-leucyl-N-[4-[(aminoiminomethyl)amino]-1S-formylbutyl]-L-leucinamide,... |
| Anwendung: | Protease inhibitor |
| CAS | 103476-89-7 |
| MW: | 475.6 D |
ab 107,00 €
COVID-19 Forschung
E64-d
Artikelnummer: LKT-E0003.1
E64d is an inhibitor of cathepsins that exhibits neuroprotective activity. In vivo, E64d inhibits cathepsin D, decreasing brain amyloid- (A ) plaque formation. E64d inhibition of cathepsins also aggravates left ventricular dysfunction in animal models of myocardial infarction.
| Schlagworte: | Aloxistatin |
| Anwendung: | Cathepsin inhibitor |
| CAS | 88321-09-9 |
| MW: | 342.43 D |
ab 126,00 €
Calpain Inhibitor I
Artikelnummer: Cay14921-1
Calpain inhibitor I is a synthetic tripeptide aldehyde that acts as a potent inhibitor of cysteine proteases including calpain I (Ki = 190 nM), calpain II (Ki = 220 nM), cathepsin B (Ki = 150 nM), and cathepsin L (Ki = 500 pM). At 10-100 µM calpain inhibitor I dose-dependently prevents the degradation of...
| Schlagworte: | Ac-Leu-Leu-Nle-Aldehyde, ALLN, MG 101, N-acetyl-L-leucyl-N-[(1S)-1-formylpentyl]-L-leucinamide |
| Anwendung: | Cysteine protease inhibitor |
| CAS | 110044-82-1 |
| MW: | 383.5 D |
ab 49,00 €
Z-FA-FMK
Artikelnummer: Cay42444-1
Z-FA-FMK is an inhibitor of cathepsin B (Ki = 1. µM). It also is an inhibitor of caspase-2, -3, -6, -7, and -9 (IC50 = 6. 15. 32. 9. and 110. µM, respectively). Z-FA-FMK inhibits severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), in a cell-free...
| Schlagworte: | Cathepsin B Inhibitor, Z-Phe-Ala-Fluoromethyl Ketone,... |
| Anwendung: | Cathepsin B inhibitor |
| CAS | 96922-64-4 |
| MW: | 386.42 D |
193,00 €