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Elastase, Human, ELISA kit
Elastase, Human, ELISA kit

Artikelnummer: HYC-HK319-01

Protein Function: Serine protease that modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Promotes cleavage of GSDMB, thereby inhibiting pyroptosis (PubMed:36899106). Promotes blood coagulation...
Schlagworte: ELANE, Elastase-2, Medullasin, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone marrow serine protease
Anwendung: ELISA
Spezies-Reaktivität: human
ab 786,00 €
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Anti-Elastase, Human, mAb 265-3K1
Anti-Elastase, Human, mAb 265-3K1

Artikelnummer: HYC-HM2174-100UG

Dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50.
Schlagworte: Anti-ELANE, Anti-Medullasin, Anti-Elastase-2, Anti-PMN elastase, Anti-Neutrophil elastase, Anti-Human leukocyte elastase,...
Anwendung: FC, ELISA, IF, IHC-P, WB
Spezies-Reaktivität: human
ab 139,00 €
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Anti-Elastase, Human, pAb
Anti-Elastase, Human, pAb

Artikelnummer: HYC-HP9027-100UG

Protein Function: Serine protease that modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Promotes cleavage of GSDMB, thereby inhibiting pyroptosis (PubMed:36899106). Promotes blood coagulation...
Schlagworte: Anti-ELANE, Anti-Medullasin, Anti-Elastase-2, Anti-PMN elastase, Anti-Neutrophil elastase, Anti-Human leukocyte elastase,...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 139,00 €
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Neutrophil Elastase Activity Assay Kit
Neutrophil Elastase Activity Assay Kit

Artikelnummer: Cay600610-192

Cayman's Neutrophil Elastase Activity Assay kit employs a specific non-fluorescent elastase substrate, (Z-Ala-Ala-Ala-Ala)2Rh110, which is selectively cleaved by elastase to yield the highly fluorescent compound R110. Fluorescence can be analyzed with an excitation wavelength of 485 nm and emission wavelength of 525...
Schlagworte: HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Neutrophile elastase detection
Spezies-Reaktivität: human
666,00 €
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Anti-Recombinant Neutrophil Elastase, clone A585
Anti-Recombinant Neutrophil Elastase, clone A585

Artikelnummer: E-AN301873L.100

Neutrophil Elastase is hematopoietic serine protease that belongs to the chymotrypsin superfamily and plays a critical role in the innate immune function of mature neutrophils and monocytes. Neutrophil elastase is actively synthesized as an inactive zymogen in myelocytic precursor cells of the bone marrow, which...
Schlagworte: Anti-ELANE, Anti-Elastase-2, Anti-Medullasin, Anti-PMN elastase, Anti-Neutrophil elastase, Anti-Human leukocyte elastase,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 304,00 €
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Anti-Recombinant ELNE, clone 5C7
Anti-Recombinant ELNE, clone 5C7

Artikelnummer: E-AN301296L.100

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes...
Schlagworte: Anti-ELANE, Anti-Elastase-2, Anti-Medullasin, Anti-PMN elastase, Anti-Neutrophil elastase, Anti-Human leukocyte elastase,...
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
391,00 €
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Human PMN Elastase ELISA Kit
Human PMN Elastase ELISA Kit

Artikelnummer: ARG80507.96

Protein function: Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. [The UniProt Consortium]
Schlagworte: Anti-HLE, Anti-ELA2, Anti-ELANE, Anti-Medullasin, Anti-Elastase-2, Anti-PMN elastase, EC=3.4.21.37, Anti-Neutrophil...
Anwendung: ELISA
Spezies-Reaktivität: human
1.134,00 €
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Mouse Neutrophil Elastase ELISA Kit
Mouse Neutrophil Elastase ELISA Kit

Artikelnummer: ARG81927.96

Protein function: Medullasin modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli, probably digests outer membrane protein A (ompA) in E.coli (PubMed:10947984). [The UniProt Consortium]
Schlagworte: Ela2, Elane, Elastase-2, EC=3.4.21.37, Leukocyte elastase, Neutrophil elastase
Anwendung: ELISA
Spezies-Reaktivität: mouse
1.118,00 €
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MeOSuc-AAPV-pNA
MeOSuc-AAPV-pNA

Artikelnummer: Cay17601-10

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to...
Schlagworte: N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
Anwendung: Neutrophil elastase & PR3 substrate
CAS 70967-90-7
MW: 590.6 D
ab 97,00 €
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Human Neutrophil Elastase Assay Reagent
Human Neutrophil Elastase Assay Reagent

Artikelnummer: Cay601014-50

Human Neutrophil Elastase Assay Reagent has been formulated and tested to work with Cayman's Assay Kits. Detailed instructions for its use are contained in the respective Cayman Assay Kit booklet.Formulation: 50 µl of human neutrophil elastase at 18 U/ml.
Schlagworte: HLE, ELA2, ELANE, Medullasin, Elastase-2, PMN elastase, EC=3.4.21.37, Neutrophil elastase, Human leukocyte elastase, Bone...
231,00 €
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Sivelestat (sodium salt hydrate)
Sivelestat (sodium salt hydrate)

Artikelnummer: Cay17779-50

Sivelestat is an inhibitor of neutrophil elastase (IC50 = 44 nM for the human enzyme). It is selective for neutrophil elastase over trypsin, thrombin, plasmin, kallikrein, chymotrypsin, and cathepsin G at 100 µM. Sivelestat inhibits the formation of neutrophil extracellular traps (NETs) induced by ionomycin...
Schlagworte: LY544349, ONO-5046, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester 2,2-dimethyl-propanoic acid,...
Anwendung: Elastase inhibitor
CAS 201677-61-4
MW: 528.5 D
ab 93,00 €
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GW311616A . HCl
GW311616A . HCl

Artikelnummer: AG-CR1-3632-M005

Solid. Soluble in DMSO or water. Potent, selective intracellular neutrophil elastase (NE, alpha-1-proteinase) inhibitor (by covalently binding to NE), Inhibits human neutrophil elastase (HNE) and is selective over other human serine proteases with IC50 values of 22nM for HNE, >,100µ,M for trypsin, cathepsin G and...
Schlagworte: (3S,3aS,6aR)-3-Isopropyl-1-(methylsulfonyl)-4-((E)-4-(piperidin-1-yl)but-2-enoyl)hexahydropyrrolo[3,2-b]pyrrol-2(1H)-one
Anwendung: Potent selective intracellular neutrophil elastase (NE alpha-1-proteinase) inhibitor
CAS 197890-44-1
MW: 434,0 D
ab 66,00 €
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