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Neutrophil Elastase Activity Assay Kit
Neutrophil Elastase Activity Assay Kit

Artikelnummer: Cay600610-192

Neutrophil elastase is stored within cytoplasmic azurophilic granules in the neutrophil and released upon stimulation by pathogens where it acts either as free protein or is associated with networks of extracellular traps (NET). Together with other proteases released from activated neutrophils, neutrophil elastase...
Schlagworte: HLE, ELA2, ELANE, Elastase-2, Medullasin, EC=3.4.21.37, PMN elastase, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Neutrophile elastase detection
Reaktivität: Human
438,00 €
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Sivelestat (sodium salt hydrate)
Sivelestat (sodium salt hydrate)

Artikelnummer: Cay17779-50

Sivelestat is a potent and selective inhibitor of neutrophil elastase (IC50 = 44 nM). It is without effect on a panel of related proteases. Sivelestat is effective in vivo, blocking elastase-dependent acute lung injury induced by intratracheal administration of LPS. Elastase inhibitors, including sivelestat, have...
Schlagworte: LY544349, ONO-5046, 4-[[[2-[[(carboxymethyl)amino]carbonyl]phenyl]amino]sulfonyl]phenyl ester 2,2-dimethyl-propanoic acid,...
Anwendung: Elastase inhibitor
CAS 201677-61-4
MW: 528.5 D
ab 62,00 €
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MeOSuc-AAPV-pNA
MeOSuc-AAPV-pNA

Artikelnummer: Cay17601-10

Proteinase 3 (PR3, myeloblastin) is a polymorphonuclear leukocyte serine proteinase that degrades matrix proteins including fibronectin, laminin, vitronectin, and collagen type IV to generate antimicrobial peptides. Neutrophil elastase is a serine proteinase that is secreted by neutrophils during inflammation to...
Schlagworte: N-(4-methoxy-1,4-dioxobutyl)-L-alanyl-L-alanyl-L-prolyl-N-(4-nitrophenyl)-L-valinamide
Anwendung: Neutrophil elastase & PR3 substrate
CAS 70967-90-7
MW: 590.6 D
ab 32,00 €
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GW311616A . hydrochloride
GW311616A . hydrochloride

Artikelnummer: AG-CR1-3632-M005

Solid. Soluble in DMSO. Slightly soluble in water and aqueous buffers. Chemical. CAS: 197890-44-1 , 198062-54-3 (free base). Formula: C19H31N3O4S . HCl. MW: 397.5 . 36.5. Synthetic. Potent, selective intracellular neutrophil elastase (NE, alpha-1-proteinase) inhibitor (by covalently binding to NE). Inhibits human...
Schlagworte: GW311616 . hydrochloride, (3S,3aS,6aR)-3-Isopropyl-1-(methylsulfonyl)-4-((E)-4-(piperidin-1-yl)but-2-enoyl)...
Anwendung: Potent selective intracellular neutrophil elastase (NE alpha-1-proteinase) inhibitor
CAS 197890-44-1
MW: 434,0 D
ab 77,00 €
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Human Neutrophil Elastase Assay Reagent
Human Neutrophil Elastase Assay Reagent

Artikelnummer: Cay601014-50

Kit component. Protein function: Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. [The UniProt Consortium]
Schlagworte: HLE, ELA2, ELANE, Medullasin, Elastase-2, PMN elastase, EC=3.4.21.37, Neutrophil elastase, Human leukocyte elastase, Bone...
125,00 €
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Neutrophil Elastase Inhibitor
Neutrophil Elastase Inhibitor

Artikelnummer: Cay14922-5

Neutrophil elastase is stored within cytoplasmic azurophilic granules in the neutrophil and released upon stimulation by pathogens where it acts either as free protein or is associated with neutrophil extracellular traps (NETs). Together with other proteases released from activated neutrophils, neutrophil elastase...
Schlagworte: 1-(3-methylbenzoyl)-1H-indazole-3-carbonitrile
Anwendung: ELANE inhibitor
CAS 1448314-31-5
MW: 261.3 D
ab 62,00 €
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Human NE/ELA2 (Elastase 2, Neutrophil) CLIA Kit
Human NE/ELA2 (Elastase 2, Neutrophil) CLIA Kit

Artikelnummer: G-HUES01066.96

ELISA Type: CLIA. Sensitivity: 0.094 ng/mL. Range: 0.156--10 ng/mL. Protein function: Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Capable of killing E.coli but not S.aureus in vitro, digests outer...
Schlagworte: HLE, ELA2, ELANE, Elastase-2, Medullasin, PMN elastase, EC=3.4.21.37, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: CLIA
Reaktivität: Human
629,00 €
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Human NE/ELA2 (Elastase 2, Neutrophil) ELISA Kit
Human NE/ELA2 (Elastase 2, Neutrophil) ELISA Kit

Artikelnummer: G-HUES02889.96

ELISA Type: Sandwich. Sensitivity: 0.469ng/mL. Range: 0.781--50ng/mL. Protein function: Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis (PubMed:15140022). Capable of killing E.coli but not S.aureus in vitro, digests outer...
Schlagworte: HLE, ELA2, ELANE, Elastase-2, Medullasin, PMN elastase, EC=3.4.21.37, Neutrophil elastase, Human leukocyte elastase, Bone...
Anwendung: Sandwich ELISA
Reaktivität: Human
566,00 €
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Mouse NE (Neutrophil Elastase) ELISA Kit
Mouse NE (Neutrophil Elastase) ELISA Kit

Artikelnummer: G-MOES00978.96

ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function: Medullasin modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli, probably digests outer membrane protein A (ompA)...
Schlagworte: Ela2, Elane, Elastase-2, EC=3.4.21.37, Leukocyte elastase, Neutrophil elastase
Anwendung: Sandwich ELISA
Reaktivität: Mouse
576,00 €
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MeOSuc-Ala-Ala-Pro-Val-AMC
MeOSuc-Ala-Ala-Pro-Val-AMC

Artikelnummer: Cay14907-10

MeOSuc-Ala-Ala-Pro-Val-AMC (MeOSuc-AAPV-AMC) is a fluorogenic substrate for human leukocyte and porcine pancreatic elastase. The methoxy succinyl (MeO-Suc) peptide AAPV is avidly hydrolyzed by these elastases but not by cathepsin G. The addition of 7-amino-4-methylcoumarin (AMC) generates a peptide of low...
Schlagworte: I 1270, MeOSuc-AAPV-AMC, Methoxy Succinyl-Ala-Ala-Pro-Val-AMC,...
Anwendung: Fluorogenic elastase substrate
CAS 72252-90-5
MW: 627.7 D
ab 32,00 €
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3,4-Dichloroisocoumarin
3,4-Dichloroisocoumarin

Artikelnummer: Cay21194-5

3,4-Dichloroisocoumarin (3,4-DCI) is a serine protease inhibitor. It completely inhibits enzyme activity of 24 serine proteases including human leukocyte elastase, thrombin, plasmin, Factor Xa, and Factor XIIa in vitro. 3,4-DCI stimulates caseinolytic activity of bovine pituitary multicatalytic proteinase complex...
Schlagworte: 3,4-DCI, 3,4-dichloro-1H-2-benzopyran-1-one
Anwendung: Irreversible Granzyme / cathepsin G / neutrophil elastase inhibitor
CAS 51050-59-0
MW: 215 D
ab 32,00 €
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JCP251
JCP251

Artikelnummer: Cay28712-10

JCP251 is a protease inhibitor. It inhibits neutrophil elastase when used at a concentration of 5 µM and reduces the activity of HIV protease and caspase-3 by 70 and 68%, respectively, when used at a concentration of 100 µM in cell-free assays. JCP251 decreases amyloid-beta (1-40) (Abeta40, Cay-21617) and Abeta42...
Schlagworte: JLK 6, 7-amino-4-chloro-3-methoxy-1H-2-benzopyran-1-one
Anwendung: Protease inhibitor, Neutrophil elastase inhibitor
CAS 62252-26-0
MW: 225.6 D
ab 124,00 €
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