Zu "K01324" wurden 56 Artikel gefunden!
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Sebetralstat
Artikelnummer: Cay45043-10
A plasma kallikrein inhibitor (IC50 = 6 nM), selective for plasma kallikrein over a panel of 14 additional proteases (IC50s = >10 µM for all), inhibits dextran sulfate-induced cleavage of kininogen-1 in isolated human plasma from 50-1,000 nM. SMILES:...
| Schlagworte: | KVD900,... |
| Anwendung: | Plasma kallikrein inhibitor |
| CAS | 1933514-13-6 |
| MW: | 491.52 D |
ab 91,00 €
Anti-KLKB1
Artikelnummer: ATA-HPA074825.100
Rabbit Polyclonal KLKB1 Antibody against Human kallikrein B1. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000109764: 61%, ENSRNOG00000014118: 65%....
| Schlagworte: | Anti-KLK3, Anti-KLKB1, EC=3.4.21.34 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
AEBSF . hydrochloride
Artikelnummer: AG-CR1-3610-M050
White solid. Soluble in water or 100% ethanol. Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF, Potent, selective inhibitor of Site-1-protease (S1P), Used to characterize the downstream result of SREBP inhibition...
| Schlagworte: | 4-(2-Aminoethyl)benzenesulfonylfluoride, Pefabloc SC |
| Anwendung: | Chymotrypsin / kallikrein / plasmin / thrombin / trypsin inhibitor, Stable PMSF alternative |
| CAS | 30827-99-7 |
| MW: | 239,7 D |
ab 44,00 €
Anti-KLKB1 / Plasma Kallikrein
Artikelnummer: ARG56296.100
Protein function: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. [The UniProt...
| Schlagworte: | Anti-KLK3, Anti-KLKB1, EC=3.4.21.34 |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
PKSI-527
Artikelnummer: Cay23974-25
PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 µM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 µM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and lambda-carrageenan ex vivo...
| Schlagworte: | 4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-benzeneacetic acid,... |
| Anwendung: | Plasma kallikrein inhibitor |
| CAS | 128837-71-8 |
| MW: | 474 D |
ab 116,00 €
PPACKII (trifluoroacetate salt)
Artikelnummer: Cay15360-1
Kallikreins are a class of serine proteases that affect the release of vasodepressor peptides or kinins from a plasma substrate. PPACKII is a specific and irreversible inhibitor of glandular and plasma kallikreins. At micromolar concentrations it has been shown to prevent apolipoprotein proteolysis in dextran...
| Schlagworte: | H-D-Phe-Phe-Arg-Chloromethyl Ketone,... |
| Anwendung: | Kallikrein inhibitor |
| CAS | 649748-23-2 |
| MW: | 729.1 D |
ab 58,00 €
N-4-Tosyl-L-arginine methyl ester (hydrochloride)
Artikelnummer: Cay17550-50
N-4-Tosyl-L-arginine methyl ester (TAME) is a synthetic substrate of serine proteases, including thrombin, trypsin, chymotrypsin, and kallikreins. It can be used to evaluate serine proteases from diverse sources. TAME also binds to and inhibits anaphase-promoting complex, a ubiquitin ligase, in Xenopus egg...
| Schlagworte: | TAME, Tosylarginine methyl ester, N2-[(4-methylphenyl)sulfonyl]-L-arginine, methyl ester, monohydrochloride |
| Anwendung: | Serine protease substrate |
| CAS | 1784-03-8 |
| MW: | 378.9 D |
ab 69,00 €
Gabexate (mesylate)
Artikelnummer: Cay23767-10
Gabexate is a competitive inhibitor of serine proteases that inhibits human thrombin, urokinase, plasmin, and Factor Xa (Kis = 0.97, 1.3, 1.6, and 8.5 µM, respectively)., It also inhibits bovine thrombin, Factor Xa, and trypsin, and porcine plasma kallikrein (Kis = 1.4, 2.1, 2.6, and 0.2 µM, respectively)., In...
| Schlagworte: | 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester, monomethanesulfonate |
| Anwendung: | Anticoagulant, plasma kallikrein inhibitor |
| CAS | 56974-61-9 |
| MW: | 417.5 D |
ab 126,00 €
Anti-Plasma Kallikrein / KLKB1, clone ACDB-11
Artikelnummer: NSJ-RQ5024
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the...
| Schlagworte: | Anti-KLK3, Anti-KLKB1, EC=3.4.21.34, Plasma Kallikrein Antibody / KLKB1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
D-Pro-Phe-Arg-pNA (hydrochloride)
Artikelnummer: Cay27569-100
D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.Formal Name:...
| Schlagworte: | D-Pro-Phe-Arg-p-nitroaniline, pFR-pNA, Plasma Kallikrein Chromogenic Substrate,... |
| Anwendung: | Photometric plasma kallikrein substrate |
| CAS | 62354-56-7 |
| MW: | 611.5 D |
ab 126,00 €
Plasma kallikrein (KLKB1), partial, human, recombinant
Artikelnummer: CSB-YP012461HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 20-390aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: GCLTQLYENA FFRGGDVASM YTPNAQYCQM RCTFHPRCLL FSFLPASSIN DMEKRFGCFL KDSVTGTLPK VHRTGAVSGH SLKQCGHQIS ACHRDIYKGV DMRGVNFNVS KVSSVEECQK RCTNNIRCQF FSYATQTFHK...
| Schlagworte: | KLK3, KLKB1, EC=3.4.21.34, Recombinant Human Plasma kallikrein (KLKB1), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 43.4 kD |
ab 242,00 €
Human KLK3 Protein, His Tag
Artikelnummer: DIM-PME101134.10
Recombinant human KLK3 protein with C-terminal 6×His tag. KLK3(Ala18-Pro261) 6×His tag, Protein function: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also...
| Schlagworte: | PSA, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, APS |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 27.7 kD |
ab 176,00 €