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AEBSF . hydrochloride
AEBSF . hydrochloride

Artikelnummer: AG-CR1-3610-M050

White solid. Soluble in water or 100% ethanol. Water soluble, irreversible serine protease (chymotrypsin, kallikrein, plasmin, thrombin and trypsin) inhibitor. Stable, non-toxic alternative to PMSF, Potent, selective inhibitor of Site-1-protease (S1P), Used to characterize the downstream result of SREBP inhibition...
Schlagworte: 4-(2-Aminoethyl)benzenesulfonylfluoride, Pefabloc SC
Anwendung: Chymotrypsin / kallikrein / plasmin / thrombin / trypsin inhibitor, Stable PMSF alternative
CAS 30827-99-7
MW: 239,7 D
ab 44,00 €
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Mouse KLKB1 / Plasma Kallikrein ELISA Kit
Mouse KLKB1 / Plasma Kallikrein ELISA Kit

Artikelnummer: ARG82751.96

Protein function: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. [The UniProt...
Schlagworte: Klk3, Klkb1, EC=3.4.21.34
Anwendung: ELISA
Spezies-Reaktivität: mouse
1.416,00 €
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Anti-KLKB1 / Plasma Kallikrein
Anti-KLKB1 / Plasma Kallikrein

Artikelnummer: ARG56296.100

Protein function: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. [The UniProt...
Schlagworte: Anti-KLK3, Anti-KLKB1, EC=3.4.21.34
Anwendung: WB, IHC (paraffin), ICC, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
624,00 €
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PKSI-527
PKSI-527

Artikelnummer: Cay23974-25

PKSI-527 is an inhibitor of plasma kallikrein (Ki = 0.81 µM). It is selective for plasma kallikrein over glandular kallikrein, plasmin, thrombin, urokinase, and Factor Xa (Kis = >500, 390, >500, 200, and >500 µM, respectively). PKSI-527 reduces bradykinin generation induced by kaolin and lambda-carrageenan ex vivo...
Schlagworte: 4-[[(2S)-2-[[[trans-4-(aminomethyl)cyclohexyl]carbonyl]amino]-1-oxo-3-phenylpropyl]amino]-benzeneacetic acid,...
Anwendung: Plasma kallikrein inhibitor
CAS 128837-71-8
MW: 474 D
ab 163,00 €
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PPACKII (trifluoroacetate salt)
PPACKII (trifluoroacetate salt)

Artikelnummer: Cay15360-1

Kallikreins are a class of serine proteases that affect the release of vasodepressor peptides or kinins from a plasma substrate. PPACKII is a specific and irreversible inhibitor of glandular and plasma kallikreins. At micromolar concentrations it has been shown to prevent apolipoprotein proteolysis in dextran...
Schlagworte: H-D-Phe-Phe-Arg-Chloromethyl Ketone,...
Anwendung: Kallikrein inhibitor
CAS 649748-23-2
MW: 729.1 D
ab 50,00 €
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N-4-Tosyl-L-arginine methyl ester (hydrochloride)
N-4-Tosyl-L-arginine methyl ester (hydrochloride)

Artikelnummer: Cay17550-50

N-4-Tosyl-L-arginine methyl ester (TAME) is a synthetic substrate of serine proteases, including thrombin, trypsin, chymotrypsin, and kallikreins. It can be used to evaluate serine proteases from diverse sources. TAME also binds to and inhibits anaphase-promoting complex, a ubiquitin ligase, in Xenopus egg...
Schlagworte: TAME, Tosylarginine methyl ester, N2-[(4-methylphenyl)sulfonyl]-L-arginine, methyl ester, monohydrochloride
Anwendung: Serine protease substrate
CAS 1784-03-8
MW: 378.9 D
ab 60,00 €
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Gabexate (mesylate)
Gabexate (mesylate)

Artikelnummer: Cay23767-10

Gabexate is a competitive inhibitor of serine proteases that inhibits human thrombin, urokinase, plasmin, and Factor Xa (Kis = 0.97, 1.3, 1.6, and 8.5 µM, respectively)., It also inhibits bovine thrombin, Factor Xa, and trypsin, and porcine plasma kallikrein (Kis = 1.4, 2.1, 2.6, and 0.2 µM, respectively)., In...
Schlagworte: 4-[[6-[(aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester, monomethanesulfonate
Anwendung: Anticoagulant, Plasma kallikrein inhibitor
CAS 56974-61-9
MW: 417.5 D
ab 109,00 €
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Anti-KLKB1 HC
Anti-KLKB1 HC

Artikelnummer: E-AB-60895.120

This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by...
Schlagworte: Anti-KLK3, Anti-KLKB1, EC=3.4.21.34, KLKB1 HC Polyclonal Antibody
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 198,00 €
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Anti-Plasma Kallikrein / KLKB1, clone ACDB-11
Anti-Plasma Kallikrein / KLKB1, clone ACDB-11

Artikelnummer: NSJ-RQ5024

Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the...
Schlagworte: Anti-KLK3, Anti-KLKB1, EC=3.4.21.34, Plasma Kallikrein Antibody / KLKB1
Anwendung: WB
Wirt: Rabbit
Spezies-Reaktivität: human
755,00 €
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D-Pro-Phe-Arg-pNA (hydrochloride)
D-Pro-Phe-Arg-pNA (hydrochloride)

Artikelnummer: Cay27569-100

D-Pro-Phe-Arg-pNA is a colorimetric substrate for plasma kallikrein. Plasma kallikrein preferentially binds to and cleaves the D-Pro-Phe-Arg (PFR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of plasma kallikrein activity.Formal Name:...
Schlagworte: D-Pro-Phe-Arg-p-nitroaniline, pFR-pNA, Plasma Kallikrein Chromogenic Substrate,...
Anwendung: Photometric plasma kallikrein substrate
CAS 62354-56-7
MW: 611.5 D
ab 109,00 €
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Anti-KLKB1
Anti-KLKB1

Artikelnummer: E-AB-66050.120

This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by...
Schlagworte: Anti-KLK3, Anti-KLKB1, EC=3.4.21.34, KLKB1 Polyclonal Antibody
Anwendung: IHC, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 198,00 €
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Anti-KLKB1
Anti-KLKB1

Artikelnummer: G-CAB13322.100

WB 1:500 - 1:2000, IF 1:50 - 1:200. Protein function: The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by...
Schlagworte: Anti-KLK3, Anti-KLKB1, EC=3.4.21.34, KLKB1 Polyclonal Antibody (CAB13322)
Anwendung: WB, IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
ab 352,00 €
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