Zu "K01322" wurden 39 Artikel gefunden!
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KYP-2047
Artikelnummer: Cay39180-1
KYP-2047 is an inhibitor of prolyl endopeptidase (Ki = 0.02 nM for the porcine enzyme). It inhibits hydrogen peroxide-induced aggregation of alpha-synuclein in SH-SY5Y cells expressing wild-type, alpha-synucleinA30P, or alpha-synucleinA53T in in vitro models of Parkinson's disease when used at a concentration of 1...
| Schlagworte: | (2S)-1-[[(2S)-1-(1-oxo-4-phenylbutyl)-2-pyrrolidinyl]carbonyl]-2-pyrrolidinecarbonitrile |
| Anwendung: | Prolyl endopeptidase inhibitor |
| CAS | 796874-99-2 |
| MW: | 339.4 D |
ab 80,00 €
HUP-55
Artikelnummer: Cay39117-1
HUP-55 is an inhibitor of prolyl endopeptidase (IC50 = 5 nM). It reduces alpha-synuclein dimerization in Neuro2a cells, induces autophagy in HEK293 cells, and decreases hydrogen peroxide-induced increases in reactive oxygen species (ROS) production in SH-SY5Y cells when used at a concentration of 10 µM. HUP-55 (10...
| Schlagworte: | (S)-1-(4-methyl-2-(3-phenylpropyl)oxazol-5-yl)pyrrolidine-2-carbonitrile |
| Anwendung: | Prolyl endopeptidase inhibitor |
| MW: | 295.4 D |
ab 48,00 €
Prolyl Oligopeptidase/Prolyl Endopeptidase, active human...
Artikelnummer: BPS-80105
Active human Prolyl oligopeptidase (POP)/Prolyl endopeptidase (PREP) (GenBank Accession No. NM_002726.) full length with N-terminal His tag, MW = 81.6 kDa, expressed in an E. coli expression system.
| Schlagworte: | PE, PEP, PREP, EC=3.4.21.26, Prolyl endopeptidase, Post-proline cleaving enzyme, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 81.6 kD |
599,00 €
Z-Gly-Pro-AMC
Artikelnummer: ABD-13477
Z-Gly-Pro-AMC is a fluorogenic substrate for the determination of post-proline cleaving enzyme (prolyl endopeptidase).
| Anwendung: | Fluorogenic PREP substrate |
| CAS | 68542-93-8 |
139,00 €
POP assay kit
Artikelnummer: BPS-80106
The Fluorogenic Prolyl OligoPeptidase (POP) Assay Kit is a complete assay system designed to measure activity of the purified POP enzyme. It comes in a convenient 96-well format, with all the reagents necessary for 100 reactions. The Fluorescent POP Activity Assay eliminates the dealing with radioactive materials...
| Schlagworte: | PE, PEP, PREP, EC=3.4.21.26, Prolyl endopeptidase, Post-proline cleaving enzyme, |
| Anwendung: | POP assays, inhibitor screening, HTS |
1.007,00 €
Pyrenophorol
Artikelnummer: BVT-0289-C500
Phytotoxic, antifungal and antihelmintic, Prolylendopeptidase inhibitor. Isolated from Phoma sp.
| Schlagworte: | Helmidiol, (-)-Pyrenophorol, (3E,5S,8R,11E,13S,16R)-5,13-Dihydroxy-8,16-dimethyl-1,9-dioxacyclohexadeca-3,11-diene-2,10-dione |
| Anwendung: | Prolylendopeptidase inhibitor |
| CAS | 155326-45-7 |
| MW: | 312,4 D |
ab 140,00 €
Anti-Prolyl Endopeptidase / PREP, Internal
Artikelnummer: ARG63978.100
Protein function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. [The UniProt Consortium]
| Schlagworte: | Anti-PE, Anti-PEP, Anti-PREP, EC=3.4.21.26, Anti-Prolyl endopeptidase, Anti-Post-proline cleaving enzyme |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-PREP/Prolyl Oligopeptidase
Artikelnummer: A305-348A
Protein function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. [The UniProt Consortium]
| Schlagworte: | Anti-PE, Anti-PEP, Anti-PREP, EC=3.4.21.26, Anti-Prolyl endopeptidase, Anti-Post-proline cleaving enzyme |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Berberine hydrochloride hydrate
Artikelnummer: LKT-B1870.10
Berberine is an isoquinoline alkaloid found in a variety of plants, including barberry, goldenseal, Oregon grape, California poppy, and the Amur cork tree. Berberine fluoresces under ultraviolet light and is often used to stain heparin in mast cells. Like many other natural products, berberine displays many...
| Schlagworte: | Berberine hydrochloride, Berberine chloride dihydrate |
| Anwendung: | AChE / prolyl oligopeptidase inhibitor |
| CAS | 633-65-8 |
| MW: | 371.82 D |
ab 79,00 €
Anti-Prolyl Endopeptidase
Artikelnummer: NSJ-R35521-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: PREP Protein function: Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long. [The UniProt Consortium]
| Schlagworte: | Anti-PE, Anti-PEP, Anti-PREP, EC=3.4.21.26, Anti-Prolyl endopeptidase, Anti-Post-proline cleaving enzyme, Prolyl... |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Pikromycin
Artikelnummer: BVT-0400-M001
Isolated from Streptomyces sp. Antibiotic. 14-Membered macrolide. Active against Gram-positive bacteria including mycobacteria. Prolyl endopeptidase (PREP) inhibitor.
| Schlagworte: | Picromycin, Amaromycin, Antibiotic B 62169A, Albomycetin |
| Anwendung: | Antibiotic |
| CAS | 19721-56-3 |
| MW: | 525,7 D |
ab 85,00 €
(S)-Laudanosine
Artikelnummer: Cay27170-1
(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium (Cay-17796) and cisatracurium (Cay-22959). (S)-Laudanosine is also an alkaloid that has been found in the prickly poppy A. platyceras. It inhibits prolyl endopeptidase with an IC50 value of 341 µM....
| Schlagworte: | (+)-Laudanosine, L-(+)-Laudanosine, L-Laudanosine, NSC 35045,... |
| Anwendung: | Bioactive isoquinoline alkaloid |
| CAS | 2688-77-9 |
| MW: | 357.4 D |
ab 92,00 €