Zu "K01314" wurden 96 Artikel gefunden!
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Anti-F10
Artikelnummer: ATA-HPA030629.100
Rabbit Polyclonal F10 Antibody against Human coagulation factor X. Validated for Western Blot. Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Interspecies information: Highest antigen sequence indentity to the following orthologs: ENSMUSG00000031444: 88%, ENSRNOG00000033444: 82%....
| Schlagworte: | Anti-F10, EC=3.4.21.6 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €
Apixaban
Artikelnummer: Cay15427-1
Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model...
| Schlagworte: | BMS 562247-01,... |
| Anwendung: | Factor Xa inhibitor |
| CAS | 503612-47-3 |
| MW: | 459.5 D |
ab 76,00 €
Rivaroxaban
Artikelnummer: Cay16043-1
Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade. It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases. In various animal arterial...
| Schlagworte: | BAY 59-7939, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide |
| Anwendung: | Factor Xa inhibitor |
| CAS | 366789-02-8 |
| MW: | 435.9 D |
ab 47,00 €
Rivaroxaban
Artikelnummer: LKT-R3584.1
An oral anticoagulant.
| Anwendung: | Anticoagulant, Factor Xa inhibitor |
| CAS | 366789-02-8 |
| MW: | 435,88 D |
ab 94,00 €
Edoxaban (tosylate)
Artikelnummer: Cay24030-1
Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated...
| Schlagworte: | DU-176b,... |
| Anwendung: | Factor Xa inhibitor |
| CAS | 480449-71-6 |
| MW: | 720.3 D |
ab 53,00 €
Apixaban-13C-d3
Artikelnummer: Cay25034-1
Apixaban-13C-d3 is intended for use as an internal standard for the quantification of apixaban (Cay-15427) by GC- or LC-MS. Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous...
| Schlagworte: | 4,5,6,7-tetrahydro-1-[4-(methoxy-13C-d3)phenyl]-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carbo... |
| Anwendung: | Internal standard, GC-MS, LC-MS, NMR |
| CAS | 1261393-15-0 |
| MW: | 463.5 D |
ab 126,00 €
Rivaroxaban-d4
Artikelnummer: Cay22563-1
Rivaroxaban-d4 is intended for use as an internal standard for the quantification of rivaroxaban (Cay-16043) by GC- or LC-MS. Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade. It...
| Schlagworte: | 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-2,3,5,6-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide |
| Anwendung: | GC-MS, LC-MS, internal standard, Factor Xa inhibitor |
| CAS | 1132681-38-9 |
| MW: | 439.9 D |
ab 283,00 €
Bz-IEGR-pNA (acetate)
Artikelnummer: Cay27567-5
Bz-IEGR-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.Formal Name:...
| Schlagworte: | Bz-Ile-Glu-Gly-Arg-pNA, Bz-Ile-Glu-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate,... |
| Anwendung: | Photometric Factor Xa substrate |
| CAS | 1325307-57-0 |
| MW: | 757.8 D |
ab 51,00 €
Eribaxaban
Artikelnummer: TGM-T31668-10mg
Description: Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism. Target: Factor Xa. Smiles: C(NC1=C(F)C=C(C=C1)N2C(=O)C=CC=C2)(=O)[C@@H]3N(C(NC4=CC=C(Cl)C=C4)=O)C[C@H](OC)C3. References: Bondarenko M,et al. Efficacy and toxicity of factor Xa...
| Schlagworte: | PD348292, PD 0348292, PD-0348292, PD-348292, PD 348292, PD0348292 |
| Anwendung: | Targets coagulation factor X [EC:3.4.21.6] (F10) |
| CAS | 536748-46-6 |
| MW: | 484.91 D |
ab 38,00 €
Anti-Factor X, clone F10-1
Artikelnummer: ARG10090.100
Protein function: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. [The UniProt Consortium]
| Schlagworte: | Anti-F10, EC=3.4.21.6 |
| Anwendung: | ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
658,00 €
Human Factor 10 (Factor X) ELISA Kit
Artikelnummer: G-HUFI00817.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
644,00 €
Betrixaban
Artikelnummer: Cay21563-100
Betrixaban is an inhibitor of the serine protease Factor Xa (Ki = 0.117 nM, IC50 = 1.5 nM), the enzyme that activates prothrombin in the blood coagulation cascade. It is selective for Factor Xa over hERG channels (Ki = 1.8 µM, IC50 = 8.9 µM), indicating a low potential for adverse cardiac effects. In vitro,...
| Schlagworte: | MK-4448, MLN1021, PRT054021, N-(5-chloro-2-pyridinyl)-2-[[4-[(dimethylamino)iminomethyl]benzoyl]amino]-5-methoxy-benzamide |
| Anwendung: | Factor Xa inhibitor |
| CAS | 330942-05-7 |
| MW: | 451.9 D |
ab 335,00 €