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Coagulation Factor X (human, recombinant)
Coagulation Factor X (human, recombinant)

Artikelnummer: Cay40252-50

Coagulation Factor X is a vitamin K-dependent plasma serine protease involved in the intrinsic, extrinsic, and common pathways of the blood coagulation cascade. It is composed of an N-terminal light chain that contains a signal sequence, a propeptide, carboxylated glutamic acid residues (Gla domain), and two EGF...
Schlagworte: F10, Stuart factor, Coagulation factor X, Stuart-Prower factor, Factor X light chain, Factor X heavy chain, Activated...
Exprimiert in: Insect cells
Ursprungsart: human
ab 399,00 €
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Human F10 (Coagulation Factor X) ELISA Kit
Human F10 (Coagulation Factor X) ELISA Kit

Artikelnummer: ELK-ELK1557.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human F10. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human F10. Next,...
Schlagworte: F10, EC=3.4.21.6
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Rat F10 (Coagulation Factor X) ELISA Kit
Rat F10 (Coagulation Factor X) ELISA Kit

Artikelnummer: ELK-ELK1558.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat F10. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat F10. Next, Avidin...
Schlagworte: F10, EC=3.4.21.6
Anwendung: ELISA
Spezies-Reaktivität: rat
ab 365,00 €
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Mouse F10 (Coagulation Factor X) ELISA Kit
Mouse F10 (Coagulation Factor X) ELISA Kit

Artikelnummer: ELK-ELK1559.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse F10. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse F10. Next,...
Schlagworte: F10, EC=3.4.21.6
Anwendung: ELISA
Spezies-Reaktivität: mouse
ab 365,00 €
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Factor Xa Inhibitor Screening Assay Kit
Factor Xa Inhibitor Screening Assay Kit

Artikelnummer: BPS-78868-1

The Factor Xa Inhibitor Screening Assay is a colorimetric assay designed to measure the activity of human Factor Xa for screening and profiling applications. The assay kit comes in a convenient 96-well format or 384-well format and contains enough purified human Factor Xa, a chromogenic substrate, and PR-02 buffer...
Schlagworte: F10, EC=3.4.21.6,
Anwendung: Inhibitor screening, HTS
Spezies-Reaktivität: human
ab 1.065,00 €
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Apixaban
Apixaban

Artikelnummer: Cay15427-1

Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model...
Schlagworte: BMS 562247-01,...
Anwendung: Factor Xa inhibitor
CAS 503612-47-3
MW: 459.5 D
ab 66,00 €
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Rivaroxaban
Rivaroxaban

Artikelnummer: Cay16043-1

Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade. It demonstrates >10,000-fold greater selectivity for Factor Xa compared to other related serine proteases. In various animal arterial...
Schlagworte: BAY 59-7939, 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
Anwendung: Factor Xa inhibitor
CAS 366789-02-8
MW: 435.9 D
ab 40,00 €
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Rivaroxaban
Rivaroxaban

Artikelnummer: LKT-R3584.1

An oral anticoagulant.
Anwendung: Anticoagulant, Factor Xa inhibitor
CAS 366789-02-8
MW: 435,88 D
ab 90,00 €
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Edoxaban (tosylate)
Edoxaban (tosylate)

Artikelnummer: Cay24030-1

Edoxaban is an orally bioavailable and potent inhibitor of factor Xa (Kis = 0.561 and 0.903 nM for free and complexed human factor Xa, respectively). It is >10,000-fold selective for factor Xa over thrombin, FVIIa/sTF, FXIa, tPA, aPC, trypsin, plasmin, and chymotrypsin. Edoxaban prolongs prothrombin, activated...
Schlagworte: DU-176b,...
Anwendung: Factor Xa inhibitor
CAS 480449-71-6
MW: 720.3 D
ab 44,00 €
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Apixaban-13C-d3
Apixaban-13C-d3

Artikelnummer: Cay25034-1

Apixaban-13C-d3 is intended for use as an internal standard for the quantification of apixaban (Cay-15427) by GC- or LC-MS. Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous...
Schlagworte: 4,5,6,7-tetrahydro-1-[4-(methoxy-13C-d3)phenyl]-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carbo...
Anwendung: Internal standard, GC-MS, LC-MS, NMR
CAS 1261393-15-0
MW: 463.5 D
ab 109,00 €
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Rivaroxaban-d4
Rivaroxaban-d4

Artikelnummer: Cay22563-1

Rivaroxaban-d4 is intended for use as an internal standard for the quantification of rivaroxaban (Cay-16043) by GC- or LC-MS. Rivaroxaban is an orally active, direct inhibitor of Factor Xa (Ki = 0.4 nM), which is a crucial component of the intrinsic and extrinsic pathways of the blood coagulation cascade. It...
Schlagworte: 5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl-2,3,5,6-d4]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide
Anwendung: GC-MS, LC-MS, Internal standard, Factor Xa inhibitor
CAS 1132681-38-9
MW: 439.9 D
ab 246,00 €
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Bz-IEGR-pNA (acetate)
Bz-IEGR-pNA (acetate)

Artikelnummer: Cay27567-5

Bz-IEGR-pNA is a colorimetric substrate for Factor Xa. Factor Xa preferentially binds to and cleaves the Ile-Glu-Gly-Arg (IEGR) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of Factor Xa activity.Formal Name:...
Schlagworte: Bz-Ile-Glu-Gly-Arg-pNA, Bz-Ile-Glu-Gly-Arg-p-nitroanilide, Factor Xa Chromogenic Substrate,...
Anwendung: Photometric Factor Xa substrate
CAS 1325307-57-0
MW: 757.8 D
ab 43,00 €
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