Zu "K01313" wurden 127 Artikel gefunden!
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Prothrombin Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01974-10ug
Description: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing. Prothrombin Protein, Human, Recombinant (His) is expressed in yeast...
| Schlagworte: | F2 , Coagulation factor II , Prothrombin |
| MW: | 67.3 kD |
ab 118,00 €
Prothrombin Protein, Human, Recombinant (E. coli, His)
Artikelnummer: TGM-TMPH-04571-100ug
Description: Prothrombin Protein, Human, Recombinant (E. coli, His) is expressed in E. coli. The accession number is P00734.
| Schlagworte: | Prothrombin , Coagulation factor II , F2 |
| MW: | 38.4 kD |
ab 82,00 €
PPACK (trifluoroacetate salt)
Artikelnummer: Cay15160-10
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
| Schlagworte: | D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, Pebac,... |
| Anwendung: | Thrombin inhibitor |
| MW: | 451 D |
ab 58,00 €
(BOC-VPR)2R110
Artikelnummer: ABD-13462
(BOC-VPR)2R110 is a sentive fluorogenic substrate for alpha-thrombin. The non-fluorescent substrate generates a bright green fluorescent R110 product that has Ex/Em = 495/520 nm, and can be easily detected with the FITC filter set. This substrate has also been used for the rapid detection of MRSA...
| Anwendung: | Fluorogenic alpha-thrombin substrate |
145,00 €
Dabigatran Acyl-beta-D-Glucuronide (trifluoroacetate salt)
Artikelnummer: Cay39046-1
Dabigatran acyl-beta-D-glucuronide is an active metabolite of the thrombin inhibitor dabigatran (Cay17133). It is formed from dabigatran primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15. Dabigatran acyl-beta-D-glucuronide (0.46 µM) increases activated partial thromboplastin time (aPTT) in isolated...
| Schlagworte: | Dabigatran beta-1-O-Acyl Glucuronide,... |
| Anwendung: | Dabigatran active metabolite |
| MW: | 647.64 D |
1.231,00 €
Dabigatran
Artikelnummer: Cay17133-1
Dabigatran is an inhibitor of thrombin (Ki = 0.0045 µM) and an active metabolite of the thrombin inhibitor prodrug dabigatran etexilate (Cay-17131). It also inhibits trypsin (Ki = 0.0503 µM) but is selective for thrombin and trypsin over plasmin, Factor Xa, activated protein C, and tissue plasminogen activator (tPA,...
| Schlagworte: | BIBR 953,... |
| Anwendung: | Thrombin inhibitor |
| CAS | 211914-51-1 |
| MW: | 471.5 D |
ab 51,00 €
p-APMSF (hydrochloride)
Artikelnummer: Cay14971-1
p-APMSF is an irreversible inhibitor of serine proteases with Ki values of 1.02, 1.18, 1.5, and 1.54 µM for bovine trypsin, human thrombin, bovine plasmin, and bovine Factor Xa, respectively. It is selective for these proteases over bovine chymotrypsin and acetylcholinesterase.Formal Name:...
| Schlagworte: | (p-Amidinophenyl)methanesulfonyl Fluoride, para-APMSF, 4-(aminoiminomethyl)-benzenemethanesulfonyl fluoride,... |
| Anwendung: | Irreversible serine protease rreversible inhibitor of serine protease |
| CAS | 74938-88-8 |
| MW: | 252.7 D |
ab 53,00 €
Dabigatran
Artikelnummer: TGM-T6295-1mg
Description: Dabigatran (BIBR 953ZW) is a THROMBIN inhibitor which acts by binding and blocking thrombogenic activity and the prevention of thrombus formation. It is used to reduce the risk of stroke and systemic EMBOLISM in patients with nonvalvular atrial fibrillation. Target: Thrombin. Smiles:...
| Schlagworte: | BIBR 953ZW, BIBR 953 |
| Anwendung: | Targets coagulation factor II (thrombin) [EC:3.4.21.5] (F2) |
| CAS | 211914-51-1 |
| MW: | 471.51 D |
ab 35,00 €
Bivalirudin
Artikelnummer: Cay23035-5
Bivalirudin is an inhibitor of alpha- and zeta-thrombin (Kis = 2.56 and 1.84 nM, respectively), enzymes that exhibit high fibrinogen-clotting activities. It is selective for alpha- and zeta-thrombin, lacking activity at trypsin and gamma-thrombin, which lacks clotting activity, at a >1,000-fold excess of...
| Schlagworte: | D-phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-a... |
| Anwendung: | alpha- & zeta-thrombin inhibitor |
| CAS | 128270-60-0 |
| MW: | 2180.3 D |
ab 97,00 €
Argatroban
Artikelnummer: LKT-A6823.10
Solid. A thrombin inhibitor that prevents tumor cell migration and bone metastasis. It has been shown to be more effective than heparin in preventing platelet loss and expression of P-selectin.
| Schlagworte: | Argatrobanum |
| Anwendung: | Thrombin inhibitor |
| CAS | 74863-84-6 |
| MW: | 508,64 D |
ab 94,00 €
Sucrose octasulfate (potassium salt)
Artikelnummer: Cay16382-1
Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 µM) and inhibit its catalytic...
| Schlagworte: | SOS, Sucrosofate potassium, 2,3,4,6-tetrakis(hydrogen sulfate),1,3,4,6-tetra-O-sulfo-beta-D-fructofuranosyl... |
| Anwendung: | Thrombin inhibitor |
| CAS | 73264-44-5 |
| MW: | 1287.5 D |
ab 134,00 €
Dabigatran etexilate-d13
Artikelnummer: Cay18451-1
Dabigatran etexilate-d13 is intended for use as an internal standard for the quantification of dabigatran etexilate (Cay-17131, Cay-35248) by GC- or LC-MS. Dabigatran etexilate is a prodrug form of the thrombin inhibitor dabigatran (Cay-17133). It inhibits thrombin-induced platelet aggregation in isolated rabbit...
| Schlagworte: | ethyl... |
| Anwendung: | MS, internal control, thrombin inhibitor, anticoagulant |
| CAS | 2749293-92-1 |
| MW: | 640.8 D |
ab 97,00 €