Zu "K01278" wurden 283 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
DPP (IV) Inhibitor Screening Assay Kit
Artikelnummer: Cay700210-96
DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by DPP (IV). GLP-1 extends the action of insulin while suppressing the release...
| Schlagworte: | Dipeptidyl peptidase IV |
| Anwendung: | DPP (IV) inhibitor screening |
| Spezies-Reaktivität: | human |
590,00 €
NEU
Cofrogliptin
Artikelnummer: Cay45049-1
A DPP-4 inhibitor (IC50 = 10.8 nM), selective for DPP-4 over DPP-8 and DPP-9 (IC50s = >100 µM for both) and a panel of 127 receptors, ion channels, transporters, and enzymes at 10 µM, decreases blood glucose levels, increases serum insulin levels, and inhibits serum DPP-4 activity in an oral glucose tolerance test...
| Schlagworte: | HSK7653,... |
| Anwendung: | DPP-4 inhibitor |
| CAS | 1844874-26-5 |
| MW: | 466.43 D |
ab 88,00 €
NEU
Retagliptin (phosphate)
Artikelnummer: Cay45052-10
A DPP-4 inhibitor, induces autophagy and inhibits alpha-MSH-induced melanogenesis in B16-F1 melanocytes at 10 and 100 µM. SMILES: O=P(O)(O)O.COC(C1=C2N(CCN(C2)C(C[C@H](N)CC3=C(C=C(C(F)=C3)F)F)=O)C(C(F)(F)F)=N1)=O. InChi Code:...
| Schlagworte: | SP2086, 7-[(3R)-3-amino-1-oxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-2... |
| Anwendung: | DPP-4 inhibitor |
| CAS | 1256756-88-3 |
| MW: | 562.36 D |
ab 75,00 €
Anti-CD26, Rat, mAb 5E8
Artikelnummer: HYC-HM3021-100UG
For immunohistology and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.
| Schlagworte: | Anti-Dpp4, Anti-GP110 glycoprotein, Anti-Dipeptidyl peptidase 4, Anti-Dipeptidyl peptidase IV, Anti-T-cell activation... |
| Anwendung: | IHC-F, ELISA, IP, WB |
| Spezies-Reaktivität: | rat |
ab 139,00 €
Anti-DPP4/CD26
Artikelnummer: E-AN006840L.100
Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme...
| Schlagworte: | Anti-Dpp4, Anti-Dipeptidyl peptidase 4, Anti-Dipeptidyl peptidase IV, Anti-Thymocyte-activating molecule, Anti-T-cell... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
ab 110,00 €
Anti-Recombinant DPP4/CD26, clone A680
Artikelnummer: E-AN301964L.100
DPP4/CD26 is a type II transmembrane glycoprotein expressed ubiquitously in most tissues and different cell types. The protein has a short cytoplasmic domain, transmembrane domain, a flexible stalk fragment and extracellular fragment. Both the catalytic peptide hydrolase domain and the beta-propeller ligand binding...
| Schlagworte: | Anti-DPP4, Anti-TP103, Anti-ADABP, Anti-Dipeptidyl peptidase 4, Anti-Dipeptidyl peptidase IV, Anti-T-cell activation... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Human CD26 ELISA Kit
Artikelnummer: ARG81437.96
Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation...
| Schlagworte: | DPP4, ADCP2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
Mouse CD26 / DPP4 ELISA Kit
Artikelnummer: ARG81712.96
Protein function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation...
| Schlagworte: | Dpp4, Cd26 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
DPPIV/CD26, His, Cynomolgus/Rhesus macaque
Artikelnummer: GSC-Z04144-100
CD26/dipeptidyl peptidase (DPP)IV is a membrane-bound protein found in many cell types of the body, and a soluble form is present in body fluids. There is longstanding evidence that various primary tumors and also metastases express DPPIV/CD26 to a variable extent.
| Schlagworte: | DPP4, Dipeptidyl peptidase 4, Dipeptidyl peptidase IV, T-cell activation antigen CD26 |
| Ursprungsart: | cynomolgus, rhesus macaque |
| MW: | 86.11 kD |
ab 524,00 €
K579
Artikelnummer: Cay42505-1
A DPP-4 inhibitor (IC50 = 5 nM for the human enzyme), reduces plasma DPP-4 activity and glucose levels and increases plasma insulin levels in an OGTT in wild-type and fa/fa Zucker fatty rats at 1 mg/kg, reduces total ulcer length in a rat model of indomethacin-induced intestinal ulcers. Formulation: A solid. InChI:...
| Schlagworte: | 1-[2S-[[4-methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile |
| Anwendung: | DPP-4 inhibitor |
| CAS | 440100-64-1 |
| MW: | 328.4 D |
ab 88,00 €
(-)-Sitagliptin (phosphate)
Artikelnummer: Cay13252-50
(-)-Sitagliptin is a potent inhibitor of dipeptidyl peptidase 4 (DPP-4, IC50 = 18 nM). It is selective for DPP-4 over DPP-8 (IC50 = 48 µM) as well as several other peptidases, including DPP-9, DPP-2, and amino peptidase P. (-)-Sitagliptin improves glucose tolerance in insulin-resistant Zucker fatty and high-fat diet...
| Schlagworte: | (R)-Sitagliptin, INN, MK-431, ONO-5435,... |
| Anwendung: | DPP4 inhibitor |
| CAS | 654671-78-0 |
| MW: | 505.3 D |
ab 56,00 €
DPP4, active human recombinant protein
Artikelnummer: BPS-80040
Active human DPP4 (GenBank Accession No. NM_001935), (amino acids 29-end) with C-terminal His tag, MW=89.1 kDa, expressed in a Baculovirus infected Sf9 cell expression system.
| Schlagworte: | ADCP2, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 89.1 kD |
722,00 €