Zu "K01254" wurden 35 Artikel gefunden!

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Acebilustat
Acebilustat

Artikelnummer: Cay33270-1

Acebilustat is an inhibitor of leukotriene A4 (LTA4) hydrolase, the rate-limiting enzyme in LTB4 synthesis. It reduces the transmigration of polymorphonuclear neutrophils (PMNs) from an epithelial monolayer to airway supernatant derived from sputum isolated from patients with cystic fibrosis when used at a...
Schlagworte: CTX-4430, 4-[[(1S,4S)-5-[[4-[4-(2-oxazolyl)phenoxy]phenyl]methyl]-2,5-diazabicyclo[2.2.1]hept-2-yl]methyl]-benzoic acid
Anwendung: LTA4 hydrolase inhibitor
CAS 943764-99-6
MW: 481.5 D
ab 62,00 €
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Bestatin (hydrochloride)
Bestatin (hydrochloride)

Artikelnummer: Cay70520-5

Bestatin is an aminopeptidase inhibitor originally isolated from S. olivoreticuli. It inhibits aminopeptidase B (IC50 = 0.05 µg/ml), aminopeptidase N (IC50 = 16.9 µM), leucine aminopeptidase (IC50 = 0.01 µg/ml), and the aminopeptidase activity of leukotriene A4 (LTA4) hydrolase (Kapp = 172 nM). It is selective for...
Schlagworte: N-(3R-amino-2S-hydroxy-1-oxo-4-phenylbutyl)-L-leucine, monohydrochloride
Anwendung: LTA4 hydrolase inhibitor
CAS 65391-42-6
MW: 344.8 D
ab 49,00 €
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ARM1
ARM1

Artikelnummer: Cay15865-5

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 µM) and conversion of LTA4 to LTB4...
Schlagworte: 4-[4-(phenylmethyl)phenyl]-2-thiazolamine
Anwendung: Leukotriene A-4 hydrolase inhibitor
CAS 68729-05-5
MW: 268.4 D
ab 62,00 €
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Anti-Leukotriene A4 Hydrolase
Anti-Leukotriene A4 Hydrolase

Artikelnummer: Cay160250-500

Leukotriene A4 hydrolase (LTA4 hydrolase) has been cloned from a variety of species including human, rat, and guinea pig. These species exhibit ~90% homology at the amino acid level. Human LTA4 hydrolase has a calculated molecular mass of 69 kDa based on the deduced amino acid sequence. Synonyms: LTA4 Hydrolase....
Schlagworte: Anti-LTA4, Anti-LTA4H, Anti-LTA-4 hydrolase, Anti-LTA-4 hydrolase, Anti-Leukotriene A-4 hydrolase, Anti-Leukotriene A-4...
Anwendung: IHC, WB
Reaktivität: Human
324,00 €
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SC-57461A
SC-57461A

Artikelnummer: Cay10108-1

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. SC-57461A is a potent, orally active inhibitor of LTA4 hydrolase that blocks ionophore-stimulated LTB4 synthesis in...
Schlagworte: N-methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl]-beta-alanine, monohydrochloride
Anwendung: LTA4 hydrolase inhibitor
CAS 423169-68-0
MW: 363.9 D
ab 32,00 €
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14,15-Leukotriene A4 methyl ester
14,15-Leukotriene A4 methyl ester

Artikelnummer: Cay10011359-100

14,15-Leukotriene A4 (14,15-LTA4) methyl ester is an esterified form of 14,15-LTA4, a leukotriene isomer formed from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by 15-lipoxygenase (15-LO) that inhibits LTA4 hydrolase. Formal Name: (5Z,8Z,10E,12E)-13-[(2S,3S)-3-pentyloxiranyl]-5,8,10,12-tridecatetraenoic...
Schlagworte: 14,15-LTA4 methyl ester, Eoxin A4 methyl ester, EXA4 methyl ester,...
Anwendung: Esterified LTA4 hydrolase inhibitor
CAS 75290-58-3
MW: 332.5 D
ab 128,00 €
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Anti-LTA4H
Anti-LTA4H

Artikelnummer: G-CAB2502.100

Anwendung: IF, IHC, WB
Reaktivität: Human, Mouse, Rat
314,00 €
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Human LTA4H (Leukotriene A4 Hydrolase) CLIA Kit
Human LTA4H (Leukotriene A4 Hydrolase) CLIA Kit

Artikelnummer: G-HUES00802.96

ELISA Type: CLIA. Sensitivity: 37.5 pg/mL. Range: 62.5--4000 pg/mL. Protein function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. [The UniProt Consortium]
Schlagworte: LTA4, LTA4H, EC=3.3.2.6, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4) hydrolase
Anwendung: CLIA
Reaktivität: Human
629,00 €
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Human LTA4H (Leukotriene A4 Hydrolase) ELISA Kit
Human LTA4H (Leukotriene A4 Hydrolase) ELISA Kit

Artikelnummer: G-HUES02444.96

ELISA Type: Sandwich. Sensitivity: 0.188ng/mL. Range: 0.313--20ng/mL. Protein function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. [The UniProt Consortium]
Schlagworte: LTA4, LTA4H, EC=3.3.2.6, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4) hydrolase
Anwendung: Sandwich ELISA
Reaktivität: Human
566,00 €
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Human Leukotriene A4 Hydrolase / LTA4H ELISA Kit
Human Leukotriene A4 Hydrolase / LTA4H ELISA Kit

Artikelnummer: G-HUFI02606.96

Anwendung: ELISA
Reaktivität: Human
629,00 €
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Human LTA4H (Leukotriene A4 Hydrolase) ELISA Kit
Human LTA4H (Leukotriene A4 Hydrolase) ELISA Kit

Artikelnummer: E-EL-H1403.96

The kit is a Sandwich enzyme immunoassay for in vitro quantitative measurement of LTA4H in serum, plasma and other biological fluids. Detection Range: 0.31--20ng/mL. Sensitivity: 0.19ng/mL. Protein function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator...
Schlagworte: LTA4, LTA4H, EC=3.3.2.6, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4) hydrolase
Anwendung: ELISA
Reaktivität: Human
554,00 €
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Anti-Leukotriene A4 hydrolase
Anti-Leukotriene A4 hydrolase

Artikelnummer: ARG56497.250

Protein function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. [The UniProt Consortium]
Schlagworte: Anti-LTA4, Anti-LTA4H, EC=3.3.2.6, Anti-LTA-4 hydrolase, Anti-Leukotriene A-4 hydrolase, Anti-Leukotriene A(4) hydrolase
Anwendung: WB
Reaktivität: Human
483,00 €
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