Zu "K01254" wurden 53 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Human LTA4H (Leukotriene A4 Hydrolase) ELISA Kit
Artikelnummer: ELK-ELK3336.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LTA4H. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LTA4H. Next,...
| Schlagworte: | LTA4, LTA4H, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4) hydrolase, Tripeptide aminopeptidase LTA4H |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mouse LTA4H (Leukotriene A4 Hydrolase) ELISA Kit
Artikelnummer: ELK-ELK6464.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse LTA4H. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse LTA4H. Next,...
| Schlagworte: | Lta4h, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4) hydrolase, Tripeptide aminopeptidase LTA4H |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Bestatin (hydrochloride)
Artikelnummer: Cay70520-5
Bestatin is an aminopeptidase inhibitor originally isolated from S. olivoreticuli. It inhibits aminopeptidase B (IC50 = 0.05 µg/ml), aminopeptidase N (IC50 = 16.9 µM), leucine aminopeptidase (IC50 = 0.01 µg/ml), and the aminopeptidase activity of leukotriene A4 (LTA4) hydrolase (Kapp = 172 nM). It is selective for...
| Schlagworte: | N-(3R-amino-2S-hydroxy-1-oxo-4-phenylbutyl)-L-leucine, monohydrochloride |
| Anwendung: | LTA4 hydrolase inhibitor |
| CAS | 65391-42-6 |
| MW: | 344.8 D |
ab 66,00 €
ARM1
Artikelnummer: Cay15865-5
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. ARM1 is a thiazolamine that inhibits LTB4 synthesis in human neutrophils (IC50 = ~0.5 µM) and conversion of LTA4 to LTB4...
| Schlagworte: | 4-[4-(phenylmethyl)phenyl]-2-thiazolamine |
| Anwendung: | Leukotriene A-4 hydrolase inhibitor |
| CAS | 68729-05-5 |
| MW: | 268.4 D |
ab 84,00 €
SC-57461A
Artikelnummer: Cay10108-1
Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. SC-57461A is a potent, orally active inhibitor of LTA4 hydrolase that blocks ionophore-stimulated LTB4 synthesis in...
| Schlagworte: | N-methyl-N-[3-[4-(phenylmethyl)phenoxy]propyl]-beta-alanine, monohydrochloride |
| Anwendung: | LTA4 hydrolase inhibitor |
| CAS | 423169-68-0 |
| MW: | 363.9 D |
ab 43,00 €
Acebilustat
Artikelnummer: Cay33270-5
Acebilustat is an inhibitor of leukotriene A4 (LTA4) hydrolase, the rate-limiting enzyme in LTB4 synthesis. It reduces the transmigration of polymorphonuclear neutrophils (PMNs) from an epithelial monolayer to airway supernatant derived from sputum isolated from patients with cystic fibrosis when used at a...
| Schlagworte: | CTX-4430, 4-[[(1S,4S)-5-[[4-[4-(2-oxazolyl)phenoxy]phenyl]methyl]-2,5-diazabicyclo[2.2.1]hept-2-yl]methyl]-benzoic acid |
| Anwendung: | LTA4 hydrolase inhibitor |
| CAS | 943764-99-6 |
| MW: | 481.5 D |
ab 84,00 €
LYS-006
Artikelnummer: Cay33706-1
LYS-006 is an inhibitor of leukotriene A4 (LTA4) hydrolase.Formal Name: betaS-amino-5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]-2H-tetrazole-2-butanoic acid. CAS Number: 1799681-85-8. Molecular Formula: C16H14ClFN6O3. Formula Weight: 392.8. Purity: >98%. Formulation: (Request formulation change), A solid....
| Schlagworte: | betaS-amino-5-[4-[(5-chloro-3-fluoro-2-pyridinyl)oxy]phenyl]-2H-tetrazole-2-butanoic acid |
| Anwendung: | LTA4 hydrolase inhibitor |
| CAS | 1799681-85-8 |
| MW: | 392.8 D |
ab 77,00 €
DG-051
Artikelnummer: Cay21688-1
DG-051 is a potent, orally bioavailable leukotriene A4 hydrolase (LTA4H) inhibitor (Kd = 25 nM, IC50 = 47 nM), the enzyme that catalyzes the rate-determining step in the synthesis of LTB4 (Cay-20110). However, it also inhibits the aminopeptidase activity of LTA4H with IC50 values of 72 and 150 nM when tested using...
| Schlagworte: | (2S)-2-[[4-(4-chlorophenoxy)phenoxy]methyl]-1-pyrrolidinebutanoic acid, monohydrochloride |
| Anwendung: | LTA4H inhibitor |
| CAS | 929915-58-2 |
| MW: | 426.3 D |
ab 43,00 €
Anti-Leukotriene A4 hydrolase
Artikelnummer: ARG56497.250
Protein function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. [The UniProt Consortium]
| Schlagworte: | Anti-LTA4, Anti-LTA4H, EC=3.3.2.6, Anti-LTA-4 hydrolase, Anti-Leukotriene A-4 hydrolase, Anti-Leukotriene A(4) hydrolase |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
656,00 €
Anti-Leukotriene A4 Hydrolase/LTA4H
Artikelnummer: A305-006A
Protein function: Epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. Has also aminopeptidase activity. [The UniProt Consortium]
| Schlagworte: | Anti-LTA4, Anti-LTA4H, EC=3.3.2.6, Anti-LTA-4 hydrolase, Anti-Leukotriene A-4 hydrolase, Anti-Leukotriene A(4) hydrolase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
LTA4H
Artikelnummer: BPS-70001
Human leukotriene A-4 hydrolase, LTA4H, (GenBank Accession No. NM_000895, a.a. 1-611(end) with C-terminal FLAG-tag and His-tag, MW = 71 kDa, expressed in a baculovirus infected Sf9 cell expression system.
| Schlagworte: | LTA4, LTA4H, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4) hydrolase, Tripeptide aminopeptidase LTA4H, |
| Anwendung: | Enzyme kinetics, screening inhibitors, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 71 kD |
547,00 €
Leukotriene A4 Hydrolase (human, recombinant)
Artikelnummer: Cay10007817-100
Leukotriene A4 hydrolase (LTA4H) is a bifunctional zinc metalloenzyme that converts LTA4 into LTB4, a potent neutrophil chemoattractant. In addition to the hydrolase activity, LTA4H also exhibits anion-dependent aminopeptidase activity. LTA4H is a potential new drug target for a variety of indications associated...
| Schlagworte: | LTA4, LTA4H, LTA-4 hydrolase, LTA-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A-4 hydrolase, Leukotriene A(4)... |
| Anwendung: | Enzyme activity, WB |
| MW: | 69 kD |
674,00 €