Zu "K01074" wurden 46 Artikel gefunden!
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4-Methylumbelliferyl 6-thio-Palmitate-beta-D-Glucopyranoside
Artikelnummer: Cay19524-1
4-Methylumbelliferyl 6-thio-palmitate-beta-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl...
| Schlagworte: | Mu-6S-Palm-beta-Glc, 4-methyl-7-[[6-S-(1-oxohexadecyl)-6-thio-beta-D-glucopyranosyl]oxy]-2H-1-benzopyran-2-one |
| Anwendung: | Fluorogenic palmitoyl-protein thioesterase substrate |
| CAS | 229644-17-1 |
| MW: | 592.8 D |
ab 73,00 €
DC661
Artikelnummer: Cay34899-10
DC661 is an inhibitor of palmitoyl-protein thioesterase 1 (PPT1) and a dimeric form of hydroxychloroquine (Cay-17911). It binds to PPT1 and inhibits PPT1 enzyme activity in A375 cells when used at concentrations of 5, 10, and 100 µM. DC661 (10 µM) inhibits autophagic flux and induces apoptosis in B-RAF mutant...
| Schlagworte: | N6-(7-chloro-4-quinolinyl)-N1-[6-[(7-chloro-4-quinolinyl)amino]hexyl]-N1-methyl-1,6-hexanediamine |
| Anwendung: | PPT1 inhibitor |
| CAS | 1872387-43-3 |
| MW: | 552.6 D |
ab 162,00 €
Anti-PPT1
Artikelnummer: ATA-HPA021546.25
Protein function: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons (PubMed:8816748). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is...
| Schlagworte: | Anti-PPT1, Anti-PPT-1, EC=3.1.2.22, Anti-Palmitoyl-protein hydrolase 1, Anti-Palmitoyl-protein thioesterase 1 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-PPT1, clone 1117CT11.2.1.4
Artikelnummer: ARG56214.100
Protein function: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons (PubMed:8816748). [The UniProt Consortium]
| Schlagworte: | Anti-PPT1, Anti-PPT-1, EC=3.1.2.22, Anti-Palmitoyl-protein hydrolase 1, Anti-Palmitoyl-protein thioesterase 1 |
| Anwendung: | WB, FC, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
616,00 €
Anti-PPT1
Artikelnummer: NSJ-R32123
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Palmitoyl-protein thioesterase 1 (PPT-1), also known as palmitoyl-protein hydrolase 1, is an enzyme that in humans is encoded by the PPT1 gene. PPT-1 is a member of the palmitoyl protein thioesterase family. The protein encoded by this gene is a small...
| Schlagworte: | Anti-PPT1, Anti-PPT-1, EC=3.1.2.22, Anti-Palmitoyl-protein hydrolase 1, Anti-Palmitoyl-protein thioesterase 1, PPT1 Antibody |
| Anwendung: | WB, IHC (paraffin), FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
PPT1 (human, recombinant)
Artikelnummer: Cay38066-100
Palmitoyl-protein thioesterase 1 (PPT1) is a lysosomal hydrolase involved in removing palmitic acid (Cay-10006627) from post-translationally modified proteins prior to their degradation. It is mainly expressed in the brain but is also found in visceral macrophages from liver, lung, and bowel tissues. PPT1...
| Schlagworte: | PPT1, PPT-1, PPT-1, Palmitoyl-protein hydrolase 1, Palmitoyl-protein hydrolase 1, Palmitoyl-protein thioesterase 1,... |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 32.7 kD |
442,00 €
Anti-CLN1
Artikelnummer: ELK-ES6725.100
The protein encoded by this gene is a small glycoprotein involved in the catabolism of lipid-modified proteins during lysosomal degradation. The encoded enzyme removes thioester-linked fatty acyl groups such as palmitate from cysteine residues. Defects in this gene are a cause of infantile neuronal ceroid...
| Schlagworte: | Anti-PPT1, Anti-PPT-1, EC=3.1.2.22, Anti-Palmitoyl-protein hydrolase 1, Anti-Palmitoyl-protein thioesterase 1, CLN1 rabbit... |
| Anwendung: | IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 173,00 €
Palmitoyl-protein thioesterase 1 (PPT1), bovine, recombinant
Artikelnummer: CSB-EP018587BO.1
Organism: Bos taurus (Bovine). Source: E.coli. Expression Region: 28-306aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: DPPAPLPLVI WHGMGDSCCN PLSMGAIKKM VEKKIPGIHV LSLEIGKTLR EDVENSFFLN VNSQVTTVCQ ILAKDPKLQQ GYNAMGFSQG...
| Schlagworte: | PPT1, CLN1, PPT-1, EC=3.1.2.22, Palmitoyl-protein hydrolase 1, Palmitoyl-protein thioesterase 1, Recombinant Bovine... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | bovine |
| MW: | 38.9 kD |
ab 364,00 €
Palmitoyl-protein thioesterase 1 (Ppt1), mouse, recombinant
Artikelnummer: CSB-MP018587MO.1
Organism: Mus musculus (Mouse). Source: Mammalian cell. Expression Region: 28-306aa. Protein Length: Full Length of Mature Protein. Tag Info: C-terminal 10xHis-tagged. Target Protein Sequence: DPPSPPPLVI WHGMGDSCCN PMSMGVIKKM VEKEIPGIYV LSLEIGKNMM EDVENSFFLN VNVQVNMVCQ ILEKDPKLQQ GYNAIGFSQG GQFLRAVAQR CPTPPMMTLI...
| Schlagworte: | Ppt1, Cln1, PPT-1, EC=3.1.2.22, Palmitoyl-protein hydrolase 1, Palmitoyl-protein thioesterase 1, Recombinant Mouse... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Mammalian cells |
| Ursprungsart: | mouse |
| MW: | 33.0 kD |
ab 125,00 €
Human PPT1 Protein, His Tag
Artikelnummer: DIM-PME101127.10
Recombinant human PPT1 protein with C-terminal 6×His tag. PPT1(Asp28-Gly306) 6×His tag, Protein function: Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons (PubMed:8816748)....
| Schlagworte: | CLN1, PPT |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 32.1 kD |
ab 176,00 €
Mu-6S-Palm-beta-Glc
Artikelnummer: TGM-T37191-1mg
Description: Mu-6S-Palm-beta-Glc is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. Upon cleavage by PPT/CLN1, it releases the fluorescent moiety 4-methylumbelliferyl...
| Anwendung: | Fluorogenic palmitoyl-protein thioesterase substrate |
| CAS | 229644-17-1 |
| MW: | 592.78 D |
ab 217,00 €
DC661
Artikelnummer: TGM-T5538-100mg
Description: DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity. Target: Apoptosis, Autophagy. Smiles: CN(CCCCCCNc1ccnc2cc(Cl)ccc12)CCCCCCNc1ccnc2cc(Cl)ccc12. References: Rebecca VW, et al. PPT1 Promotes Tumor...
| Anwendung: | PPT1 inhibitor |
| CAS | 1872387-43-3 |
| MW: | 552.58 D |
ab 69,00 €