Zu "K01052" wurden 36 Artikel gefunden!
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4-Methylumbelliferyl Palmitate
Artikelnummer: Cay16089-100
Cholesterol ester storage disease and Wolman disease are recessive autosomal disorders caused by a deficiency in lysosomal acid lipase (LAL), also known as cholesteryl ester hydrolase. 4-Methylumbelliferyl palmitate (4-MUP) is a fluorogenic substrate for lysosomal acid lypase (LAL). 4-MUP is cleaved by LAL to...
| Schlagworte: | 4-MU Palmitate, 4-MUP, Palmitoyl 4-Methylumbelliferone, hexadecanoic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl ester |
| Anwendung: | Fluorogenic LAL / Cholesteryl esterase substrate |
| CAS | 17695-48-6 |
| MW: | 414.6 D |
ab 115,00 €
Lalistat 2
Artikelnummer: Cay25347-5
Lalistat 2 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 152 nM using purified human LAL). It blocks lipid clearance induced by the autophagy enhancers MSL and MSL-7 in HeLa cells preloaded with palmitic acid (Cay-10006627) and oleic acid (Cay-90260).Formal Name: 1-piperidinecarboxylic acid,...
| Schlagworte: | 1-piperidinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester |
| Anwendung: | Lysosomal acid lipase inhibitor |
| CAS | 1234569-09-5 |
| MW: | 296.4 D |
ab 127,00 €
Lalistat 1
Artikelnummer: Cay23891-1
Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM using purified human LAL). It is selective for LAL over human pancreatic and bovine milk lipoprotein lipases up to a concentration of 10 µM. Lalistat 1 (0.01-10 µM) reduces cholesterol accumulation in lysosome-like storage organelles in GM03123...
| Schlagworte: | 4-morpholinecarboxylic acid, 4-(1-piperidinyl)-1,2,5-thiadiazol-3-yl ester |
| Anwendung: | LAL inhibitor |
| CAS | 501104-16-1 |
| MW: | 298.4 D |
ab 67,00 €
4-Methylumbelliferyl Oleate
Artikelnummer: Cay19590-50
4-Methylumbelliferyl (4-MU) oleate is a fluorogenic substrate for acid and alkaline lipases. It is cleaved by lipases, liberating 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively.Formal Name:...
| Schlagworte: | 4-Methylumbelliferone Oleate, 4-MU Oleate, 4-MUO, 7-hydroxy-4-Methylcoumarin Oleate, 9Z-octadecenoic... |
| Anwendung: | Fluorogenic lipase substrate |
| CAS | 18323-58-5 |
| MW: | 440.6 D |
ab 72,00 €
Lalistat 2
Artikelnummer: TGM-T41160-500mg
Description: Lalistat 2 is a selective inhibitor of lysosomal acid lipase with IC50 of 152 nM and exhibits no inhibition of human pancreatic lipase or bovine milk lipoprotein lipase (up to 10 µM). Target: Lipase. Smiles: O=C(Oc1nsnc1N1CCCCC1)N1CCCCC1. References: Rosenbaum et al (2009) Chemical screen to reduce...
| Anwendung: | Lysosomal acid lipase inhibitor |
| CAS | 1234569-09-5 |
| MW: | 296.39 D |
ab 37,00 €
Lysosomal Acid Lipase Activity MaxSpec(R) Assay Kit
Artikelnummer: Cay24854-1
Lysosomal acid lipase (LAL) is a lysosomal enzyme that hydrolyzes cholesteryl esters and triglycerides to produce cholesterol, glycerol, and free fatty acids. LAL deficiency is due to mutations in the LAL gene, LIPA, that lead to decreases in LAL activity. Wolman's disease is a severe form of LAL deficiency that...
| Schlagworte: | LAL |
| Anwendung: | LC-MS/MS, fluorometry, LAL activity determination |
407,00 €
Anti-LIPA
Artikelnummer: E-AB-19021.120
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced...
| Schlagworte: | Anti-LAL, Anti-LIPA, Anti-Lipase A, EC=3.1.1.13, Anti-Sterol esterase, Anti-Cholesteryl esterase, Anti-Acid cholesteryl... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-LIPA
Artikelnummer: E-AB-52935.120
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced...
| Schlagworte: | Anti-LAL, Anti-LIPA, Anti-Lipase A, EC=3.1.1.13, Anti-Sterol esterase, Anti-Cholesteryl esterase, Anti-Acid cholesteryl... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-LIPA
Artikelnummer: ATA-HPA057052.100
Protein function: Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence...
| Schlagworte: | Anti-LAL, Anti-LIPA, Anti-Lipase A, Anti-Sterol esterase, Anti-Cholesteryl esterase, Anti-Acid cholesteryl ester... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Mouse LIPA (Lipase A, Lysosomal Acid) ELISA Kit
Artikelnummer: ELK-ELK7101.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse LIPA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse LIPA. Next,...
| Schlagworte: | LAL, Lip1, Lipa, Lipase A, Sterol esterase, Cholesteryl esterase, Acid cholesteryl ester hydrolase, Lysosomal acid... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA),...
Artikelnummer: CSB-EP012972HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 22-399aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal GST-tagged. Target Protein Sequence: SGGKLTAVDP ETNMNVSEII SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD SSNWVTNLAN SSLGFILADA GFDVWMGNSR GNTWSRKHKT LSVSQDEFWA...
| Schlagworte: | LAL, LIPA, Lipase A, Sterol esterase, Cholesteryl esterase, Acid cholesteryl ester hydrolase, Lysosomal acid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 70 kD |
ab 219,00 €
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA),...
Artikelnummer: CSB-EP012972HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 22-399aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: SGGKLTAVDP ETNMNVSEII SYWGFPSEEY LVETEDGYIL CLNRIPHGRK NHSDKGPKPV VFLQHGLLAD SSNWVTNLAN SSLGFILADA GFDVWMGNSR GNTWSRKHKT LSVSQDEFWA...
| Schlagworte: | LAL, LIPA, Lipase A, Sterol esterase, Cholesteryl esterase, Acid cholesteryl ester hydrolase, Lysosomal acid... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 47.1 kD |
ab 219,00 €