Zu "K01049" wurden 264 Artikel gefunden!
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Amplite(TM) Colorimetric Acetylcholinesterase Assay Kit
Artikelnummer: ABD-11400
Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...
| Anwendung: | Acetylcholinesterase assays |
291,00 €
Acetylcholinesterase (eel)
Artikelnummer: Cay44687-10
Acetylcholinesterase (AChE) is a highly conserved homotetrameric carboxylesterase that is composed of four ~70 kDa subunits, each containing a single active site. In the electric eel (E. electricus), AChE is highly expressed in the electric organs at the posterior innervated membrane, where it hydrolyzes...
| Schlagworte: | AChE |
| Anwendung: | Active enzyme |
646,00 €
Acetylcholinesterase Activity Assay Kit
Artikelnummer: Cay502863-96
Cayman's Acetylcholinesterase Activity Assay Kit provides a convenient method of detecting total cholinesterase (ChE) and/or AChE activity in serum, plasma, tissue homogenates, and cell lysates. This assay enables the specific detection of AChE activity by leveraging Cayman's proprietary BChE inhibitor formulated to...
| Schlagworte: | AChE Activity Assay Kit |
| Anwendung: | Total cholinesterase (ChE) / AChE activity detection |
398,00 €
Ipidacrine
Artikelnummer: TGM-T7891-25mg
Description: Ipidacrine (NIKâ??247) (NIKâ??247) is an Antidementia Agent. Target: Potassium Channel, Sodium Channel, Cholinesterase (ChE), Others. Smiles: Nc1c2CCCc2nc2CCCCc12. References: Kojima J , Onodera K , Ozeki M , et al. Ipidacrine (NIK7): A Review of Multiple Mechanisms as an Antidementia Agent[J]. CNS...
| Schlagworte: | NIKâEUR247 |
| Anwendung: | AChE inhibitor |
| CAS | 62732-44-9 |
| MW: | 188.27 D |
ab 29,00 €
Acotiamide (hydrochloride)
Artikelnummer: Cay43731-1
Acotiamide is an inhibitor of acetylcholinesterase (AChE, IC50 = 0.384 µM). It potentiates ACh-induced contraction of isolated guinea pig gastric and antrum strips when used at a concentration of 3 µM. Formulations containing acotiamide have been used in the treatment of functional dyspepsia. SMILES...
| Schlagworte: | YM-443, N-[2-[bis(1-methylethyl)amino]ethyl]-2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxamide,... |
| Anwendung: | AChE inhibitor |
| CAS | 185104-11-4 |
| MW: | 487.01 D |
ab 103,00 €
Edrophonium-d5 (chloride)
Artikelnummer: Cay43808-1
An internal standard for the quantification of edrophonium by GC- or LC-MS
| Schlagworte: | N-(ethyl-d5)-3-hydroxy-N,N-dimethylbenzenaminium, monochloride |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, AChE inhibitor |
| MW: | 206.72 D |
ab 133,00 €
Acotiamide-d6 (hydrochloride)
Artikelnummer: Cay43489-1
An internal standard for the quantification of acotiamide by GC- or LC-MS. Formulation: A solid. InChI: InChI=1S/C21H30N4O5S.ClH/c1-12(2)25(13(3)4)8-7-22-20(28)15-11-31-21(23-15)24-19(27)14-9-17(29-5)18(30-6)10-16(14)26,/h9-13,26H,7-8H2,1-6H3,(H,22,28)(H,23,24,27),1H/i5D3,6D3,. InChIKey: VQEKQYLTAIVCBW-PKKCSIJHSA-N....
| Schlagworte: | N-(2-(diisopropylamino)ethyl)-2-(2-hydroxy-4,5-bis(methoxy-d3)benzamido)thiazole-4-carboxamide, monohydrochloride |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, AChE inhibitor |
| MW: | 493.05 D |
631,00 €
Donepezil hydrochloride
Artikelnummer: LKT-D5753.100
Donepezil hydrochloride is a centrally acting reversible acetylcholinesterase inhibitor. Its main therapeutic use is in the treatment of Alzheimer's disease.
| Schlagworte: | Aricept, Donepezil HCl |
| Anwendung: | Acetylcholinesterase inhibitor |
| CAS | 120011-70-3 |
| MW: | 415,95 D |
ab 125,00 €
Donepezil
Artikelnummer: Cay13245-10
Donepezil is an inhibitor of acetylcholinesterase (AChE, IC50 = 6.7 nM). It is selective for AChE over butyrylcholinesterase (BChE, IC50 = 988 nM). Donepezil (0.1 and 1 µM) inhibits the production of nitric oxide (NO) and TNF-alpha induced by oligomeric amyloid-beta (1-42) (AbetaO1-42) in primary rat microglial...
| Schlagworte: | Aricept(R), 2,3-dihydro-5,6-dimethoxy-2[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one |
| Anwendung: | AChE inhibitor |
| CAS | 120014-06-4 |
| MW: | 379.5 D |
ab 49,00 €
PE154
Artikelnummer: Cay42396-1
PE154 is an inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE, IC50s = 0. and 16 nM, respectively). It is also a fluorescent probe for amyloid-ß (Aß) plaques that displays excitation and emission maxima of 405 and 517 nm, respectively. PE154 selectively binds to Aß over phosphorylated tau in a...
| Schlagworte: | 4-[[[7-(diethylamino)-2,4-dioxo-2H-1-benzopyran-3(4H)-ylidene]methyl]amino]-benzeneacetic acid,... |
| Anwendung: | AChE / BChE inhibitor |
| CAS | 1192750-33-6 |
| MW: | 589.68 D |
ab 53,00 €
Amplite(TM) Fluorimetric Acetylcholinesterase Assay Kit...
Artikelnummer: ABD-11401
Acetylcholinesterase, also known as AChE, is an enzyme that degrades (through its hydrolytic activity) the neurotransmitter acetylcholine, producing choline and an acetate group. It is mainly found at neuromuscular junctions and cholinergic synapses in the central nervous system, where its activity serves to...
| Anwendung: | Acetylcholinesterase assays |
291,00 €
beta-Amyrin
Artikelnummer: Cay20949-1
beta-Amyrin is a natural pentacyclic triterpenoid commonly found in plants. It is a member of the oleanane group of secondary metabolites biosynthesized from squalene in the triterpenoid pathway. beta-Amyrin inhibits collagen-induced platelet aggregation (IC50 = 10.5 µM), inhibits acetylcholinesterase (IC50 = 165...
| Schlagworte: | (+)-beta-Amyrin, NSC 527971, Olean-12-en-3beta-ol, (3beta)-olean-12-en-3-ol |
| Anwendung: | Collagen-induced platelet aggregation inhibitor, acetylcholinesterase inhibitor |
| CAS | 559-70-6 |
| MW: | 426.7 D |
ab 130,00 €