Zu "K01047" wurden 266 Artikel gefunden!
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Anti-PLA2G3
Artikelnummer: NSJ-RQ8852
0.5mg/ml if reconstituted with 0.2ml sterile DI water. This gene encodes a protein that belongs to the secreted phospholipase A2 family, whose members include the bee venom enzyme. The encoded enzyme functions in lipid metabolism and catalyzes the calcium-dependent hydrolysis of the sn-2 acyl bond of phospholipids...
| Schlagworte: | Anti-PLA2G3, Anti-Group 3 secretory phospholipase A2, Anti-Group III secretory phospholipase A2, Anti-Phosphatidylcholine... |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
PLA2G1B hFc Chimera, Mouse
Artikelnummer: GSC-Z06314-100
Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic...
| Schlagworte: | Pla2g1b, PLA2-Ib, Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B |
| Ursprungsart: | mouse |
| MW: | 40.9 kD |
ab 457,00 €
Mouse Phospholipase A2 IIA ELISA Kit
Artikelnummer: ARG82429.96
Protein function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:8425615). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins....
| Schlagworte: | EF, Pla2g2a, GIIC sPLA2, Enhancing factor, Group IIA phospholipase A2, Phospholipase A2, membrane associated,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
1.118,00 €
Human Phospholipase A2 IIA ELISA Kit
Artikelnummer: ARG82428.96
Protein function: Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins...
| Schlagworte: | PLA2B, PLA2G2A, NPS-PLA2, GIIC sPLA2, Group IIA phospholipase A2, Phospholipase A2, membrane associated,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.118,00 €
PLA2G1B, His, Human
Artikelnummer: GSC-Z05755-100
Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic...
| Schlagworte: | PLA2G1B, Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B |
| Ursprungsart: | human |
| MW: | 15.23 kD |
ab 524,00 €
PLA2G1B hFc Chimera, Human
Artikelnummer: GSC-Z05756-100
Phospholipase A2 (PLA2) plays crucial roles in diverse cellular responses, including phospholipid digestion and metabolism, host defense and signal transduction. PLA2 provides precursors for generation of eicosanoids, such as prostaglandins (PGs) and leukotrienes (LTs), when the cleaved fatty acid is arachidonic...
| Schlagworte: | PLA2G1B, Phospholipase A2, Group IB phospholipase A2, Phosphatidylcholine 2-acylhydrolase 1B |
| Ursprungsart: | human |
| MW: | 40.9 kD |
ab 457,00 €
sPLA2 (human, recombinant Type V)
Artikelnummer: Cay10009563-25
Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids. PLA2 (Type V) is a secretory PLA2 (sPLA2) of approximately 14 kDa and is one of the isoforms in the growing list of the PLA2 enzyme family. This enzyme, rather than the sPLA2 (Type II), is responsible for...
| Schlagworte: | PLA2G5, PLA2-10, PLA2-10, Phospholipase A2 group V, Phospholipase A2 group V, Phosphatidylcholine 2-acylhydrolase 5,... |
| Anwendung: | Enzyme activity, WB |
| MW: | 14 kD |
577,00 €
CAY10502
Artikelnummer: Cay10008657-1
Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position leading to the production of lysophospholipids and free fatty acids. Calcium-dependent cytosolic PLA2 (cPLA2alpha) is a 85 kDa enzyme that plays a key role in the arachidonic cascade and the inflammatory response associated with...
| Schlagworte: | 1-[3-[4-(decyloxy)phenoxy]-2-oxopropyl]-1H-indole-3,5-dicarboxylic acid, 3-methyl ester |
| Anwendung: | cPLA2 inhibitor |
| CAS | 888320-29-4 |
| MW: | 523.6 D |
ab 68,00 €
LY315920
Artikelnummer: Cay18267-5
LY315920 is an inhibitor of human group IIA (hGIIA) secretory phospholipase A2 (sPLA2, IC50 = 9 nM). It also potently inhibits human GIIE and GX isoforms, as well as the corresponding mouse isoforms, but poorly inhibits other PLA2 enzymes. LY315920 inhibits sPLA2-induced release of thromboxane A2 from isolated...
| Schlagworte: | Varespladib, 2-[[3-(2-amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]-acetic acid |
| Anwendung: | Secretory phospholipase A2 (PLA2) inhibitor |
| CAS | 172732-68-2 |
| MW: | 380.4 D |
ab 128,00 €
ONO-RS-082
Artikelnummer: Cay20243-100
ONO-RS-082 is a reversible inhibitor of Ca2+-independent phospholipase A2. At 3.5 µM, it has been shown to inhibit epinephrine-stimulated thromboxane production in human platelets. ONO-RS-082 can also disrupt endosome tubule formation and maintenance of the Golgi complex.Formal Name:...
| Schlagworte: | 4-chloro-2-[[(2E)-1-oxo-3-(4-pentylphenyl)-2-propen-1-yl]amino]-benzoic acid |
| Anwendung: | Reversible Ca2+-independent phospholipase A2 inhibitor |
| CAS | 99754-06-0 |
| MW: | 371.9 D |
ab 193,00 €
CAY10590
Artikelnummer: Cay13181-1
Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids, liberating arachidonic acid for subsequent eicosanoid synthesis. Three primary types of PLA2 exist: secretory (sPLA2), calcium-dependent cytosolic (cPLA2), and calcium-independent cytosolic (iPLA2). Of these...
| Schlagworte: | 4-[(1-oxo-7-phenylheptyl)amino]-(4R)-octanoic acid |
| Anwendung: | sPLA2 inhibitor |
| CAS | 1101136-50-8 |
| MW: | 347.5 D |
ab 56,00 €
Thioetheramide-PC
Artikelnummer: Cay62750-5
Thioetheramide-PC is a structurally modified phospholipid that functions as a competitive, reversible inhibitor of secretory phospholipase A2 (sPLA2). The IC50 value for thioetheramide-PC is 2 µM at a substrate concentration of 0.5 mM. In addition to binding to the catalytic site of sPLA2, thioetheramide-PC also...
| Schlagworte: | 1-Palmitylthio-2-palmitoylamido-1,2-dideoxy-sn-glycero-3-phosphorylcholine,... |
| Anwendung: | sPLA2 inhibitor |
| CAS | 116457-99-9 |
| MW: | 735.1 D |
ab 104,00 €