Zu "K00923" wurden 80 Artikel gefunden!
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Roginolisib
Artikelnummer: Cay44445-25
Roginolisib is an inhibitor of PI3Kdelta (IC50 = 0. µM). It is selective for PI3Kdelta over PI3Kalpha, PI3Kbeta, PI3Kgamma, VPS34, and PI3KC2beta (IC50s = 0. 1. 10. 5. and 5. µM, respectively). Roginolisib inhibits the growth of SU-DHL-6 B cell lymphoma cells that endogenously express PI3Kdelta (GI50 = 0. µM) but...
| Schlagworte: | IOA-244, MSC2360844,... |
| Anwendung: | PI3Kdelta inhibitor |
| CAS | 1305267-37-1 |
| MW: | 526.58 D |
ab 299,00 €
Anti-PIK3C2A / Phosphoinositide 3-kinase-C2-alpha
Artikelnummer: NSJ-FY12818
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PIK3C2A antibody detects Phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing alpha polypeptide, a lipid kinase that regulates membrane trafficking, signal transduction, and cytoskeletal organization. Encoded by the PIK3C2A gene on...
| Schlagworte: | Anti-PIK3C2A, Anti-Phosphoinositide 3-kinase-C2-alpha, Anti-Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing... |
| Anwendung: | WB, ICC/IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
Anti-PIK3C2B / Phosphoinositide 3-kinase-C2-beta
Artikelnummer: NSJ-FY12329
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PIK3C2B antibody is used to study Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta, a class II phosphoinositide 3-kinase that generates phosphatidylinositol 3-phosphate and phosphatidylinositol 3,4-bisphosphate to...
| Schlagworte: | Anti-PIK3C2B, Anti-C2-PI3K, Anti-Phosphoinositide 3-kinase-C2-beta, Anti-Phosphatidylinositol 4-phosphate 3-kinase C2... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
AZD 6482
Artikelnummer: Cay15250-1
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of the 3' hydroxyl position of PIs to produce the second messengers PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3. PI3Kalpha, beta, and delta are class 1A enzymes composed of p110 and p85 subunits, whereas PI3Kgamma is a class 1B PI3K composed of a p110...
| Schlagworte: | KIN-193, 2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]-benzoic acid |
| Anwendung: | PI3K inhibitor |
| CAS | 1173900-33-8 |
| MW: | 408.5 D |
ab 51,00 €
17beta-hydroxy Wortmannin
Artikelnummer: Cay13812-500
17beta-hydroxy Wortmannin is an analog of wortmannin. It irreversibly binds phosphoinositide 3-kinase (PI3K) and potently blocks fMLP-stimulated respiratory burst in neutrophils (IC50 = 5 nM). 17beta-hydroxy Wortmannin inhibits recombinant PI3K and mTOR (IC50 = 2.7 and 193 nM, respectively) and prevents the growth...
| Schlagworte: | 17beta-hydroxy-11-(acetyloxy)-1S,6bR,7,8,9aS,10,11R,11bR-octahydro-1-(methoxymethyl)-9a,11b-dimethyl-3H-furo[4,3,2-de]inde... |
| Anwendung: | PI3K inhibitor |
| CAS | 58053-83-1 |
| MW: | 430.4 D |
ab 91,00 €
Viridiol
Artikelnummer: Cay19607-1
Viridiol is a fungal steroid that demonstrates phytotoxic activity. It is a metabolite of the fungistatic compound, viridin. Both viridin and viridiol are reported to inhibit PI3K.Formal Name: 1beta,3beta-dihydroxy-2beta-methoxy-18-norandrosta-5,8,11,13-tetraeno[6,5,4-bc]furan-7,17-dione. CAS Number: 23820-80-6....
| Schlagworte: | NSC 658706, 1beta,3beta-dihydroxy-2beta-methoxy-18-norandrosta-5,8,11,13-tetraeno[6,5,4-bc]furan-7,17-dione |
| Anwendung: | Phytotoxic agent, PI3K inhibitor, viridin metabolite |
| CAS | 23820-80-6 |
| MW: | 354.4 D |
ab 89,00 €
Anti-phospho-PIK3C2B (Tyr228)
Artikelnummer: ARG55596.100
Protein function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns. Does not phosphorylate PtdIns(4,5)P2. May be involved in EGF and PDGF signaling cascades. [The UniProt Consortium]
| Schlagworte: | Anti-phospho-PIK3C2B, Anti-phospho-C2-PI3K, EC=2.7.1.154, Anti-phospho-PI3K-C2-beta, Anti-phospho-PtdIns-3-kinase C2... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-PIK3C2A, C-terminal
Artikelnummer: ARG63599.100
Protein function: Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second messengers. Has a role in several intracellular trafficking events. Functions in insulin signaling and secretion. Required for translocation of the glucose transporter...
| Schlagworte: | Anti-PIK3C2A, EC=2.7.1.154, Anti-PI3K-C2-alpha, Anti-PtdIns-3-kinase C2 subunit alpha, Anti-Phosphoinositide... |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-PIK3C2A
Artikelnummer: NSJ-R36313-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Phosphoinositide-3-kinase, class 2, alpha Protein function: Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) that act as second...
| Schlagworte: | Anti-PIK3C2A, EC=2.7.1.154, Anti-PI3K-C2-alpha, Anti-PtdIns-3-kinase C2 subunit alpha, Anti-Phosphoinositide... |
| Anwendung: | IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
PF-4989216
Artikelnummer: Cay19308-1
PF-4989216 is an orally bioavailable broad-spectrum PI3K inhibitor (IC50s = 2, 142, 65, 1, and 110 nM for p110alpha, p110beta, p110gamma, p110delta, and VPS34, respectively). It inhibits the cell viability of small-cell lung cancer (SCLC) cells with a mutation in PIK3CA, blocking PI3K downstream signaling and...
| Schlagworte: | 4-(4-cyano-2-fluorophenyl)-2-(4-morpholinyl)-5-(1H-1,2,4-triazol-5-yl)-3-thiophenecarbonitrile |
| Anwendung: | PI3K inhibitor |
| CAS | 1276553-09-3 |
| MW: | 380.4 D |
ab 69,00 €
Anti-PIK3C2G
Artikelnummer: G-PACO07210.50
PIK3C2G Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, WB applications. PIK3C2G Antibody is a high quality polyclonal antibody for research use only.. Protein function: Generates phosphatidylinositol 3-phosphate (PtdIns3P) and phosphatidylinositol...
| Schlagworte: | Anti-PIK3C2G, EC=2.7.1.154, Anti-PI3K-C2-gamma, Anti-PtdIns-3-kinase C2 subunit gamma, Anti-Phosphoinositide... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
225,00 €
Anti-PIK3C2B
Artikelnummer: ATA-HPA030515.100
Protein function: Phosphorylates PtdIns and PtdIns4P with a preference for PtdIns (PubMed:10805725, PubMed:9830063, PubMed:11533253). Does not phosphorylate PtdIns(4,5)P2 (PubMed:9830063). May be involved in EGF and PDGF signaling cascades (PubMed:10805725). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH...
| Schlagworte: | Anti-PIK3C2B, Anti-C2-PI3K, Anti-PI3K-C2-beta, Anti-PtdIns-3-kinase C2 subunit beta, Anti-Phosphoinositide... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €