Zu "K00922" wurden 384 Artikel gefunden!
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LY294002
Artikelnummer: Cay70920-5
LY294002 is a multi-kinase inhibitor. It inhibits casein kinase 2 (CK2, IC50 = 0.098 µM), the PI3K subunits p110alpha, p110beta, p110delta, and p110gamma (IC50s = 0.497, 0.554, 0.331, and 3.8 µM, respectively), and DNA protein kinase (DNA-PK, IC50 = 6 µM), among other kinases, as well as CK1, GSK3alpha, and GSK3beta...
| Schlagworte: | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Anwendung: | PI3K inhibitor |
| CAS | 154447-36-6 |
| MW: | 307.3 D |
ab 44,00 €
PI-3 Kinase Lipid Substrate
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
| Anwendung: | PI-3 kinase substrate |
581,00 €
Wortmannin
Artikelnummer: Cay10010591-1
By phosphorylating phosphatidylinositol, phosphoinositide 3-kinases (PI3K), activates diverse cellular functions, including cell growth, differentiation, survival, and motility. Wortmannin is a potent, cell-permeable, and irreversible inhibitor of PI3K enzymes (IC50 = 1-10 nM). However, the class II PI3Ks from...
| Schlagworte: | KY 12420,... |
| Anwendung: | PI3K inhibitor |
| CAS | 19545-26-7 |
| MW: | 428.4 D |
ab 74,00 €
NEU
Anti-Recombinant PI3-Kinase catalytic subunit alpha,...
Artikelnummer: E-AN303413L.100
Protein function: Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides (PubMed:15135396, PubMed:23936502, PubMed:28676499). Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to...
| Schlagworte: | Anti-PIK3CA, Anti-Phosphoinositide 3-kinase alpha, Anti-Serine/threonine protein kinase PIK3CA,... |
| Anwendung: | WB, ICC/IF, FCM, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant PI3-Kinase p110 beta, clone C333034
Artikelnummer: E-AN303414L.100
Protein function: Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol derivatives at position 3 of the inositol ring to produce 3-phosphoinositides (PubMed:15135396). Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3)...
| Schlagworte: | Anti-PIK3CB, Anti-Serine/threonine protein kinase PIK3CB, Anti-Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 171,00 €
NEU
Anti-Recombinant PI 3-Kinase p110delta, clone C112333
Artikelnummer: E-AN302713L.100
Protein function: Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides (PubMed:9235916). Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol...
| Schlagworte: | Anti-PIK3CD, Anti-Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant PI3-Kinase p110 delta, clone C173035
Artikelnummer: E-AN303415L.100
Protein function: Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides (PubMed:9235916). Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol...
| Schlagworte: | Anti-PIK3CD, Anti-Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit delta,... |
| Anwendung: | WB, ICC/IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
3-Methyladenine
Artikelnummer: Cay13242-25
Autophagy is a multi-step process that involves the degradation and digestion of intracellular components by the lysosome. This process allows cells to efficiently mobilize and recycle cellular constituents, and also prevents the accumulation of damaged organelles, misfolded proteins, and invading microorganisms....
| Schlagworte: | 3-MA, NSC 66389, 3-methyl-3H-purin-6-amine |
| Anwendung: | PI3K inhibitor |
| CAS | 5142-23-4 |
| MW: | 149.2 D |
ab 53,00 €
Recombinant Human PI3 Kinase p110 alpha Protein
Artikelnummer: ABS-PP-26037.100
Tag: C-His. Modification: unmodified. Start Site: Val131. End Site: Gly320. Coverage: 0.18. Isoelectric Point: 9. Core Sequence: VKDPEVQDFR RNILNVCKEA VDLRDLNSPH SRAMYVYPPN VESSPELPKH IYNKLDKGQI IVVIWVIVSP NNDKQKYTLK INHDCVPEQV IAEAIRKKTR SMLLSSEQLK LCVLEYQGKY ILKVCGCDEY FLEKYPLSQY KYIRSCIMLG RMPNLMLMAK ESLYSQLPMD...
| Schlagworte: | PIK3CA, Phosphoinositide 3-kinase alpha, Serine/threonine protein kinase PIK3CA, Phosphoinositide-3-kinase catalytic alpha... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 24.5 kD |
ab 90,00 €
Recombinant Human PI3 Kinase p110 alpha Protein
Artikelnummer: ABS-PP-26037-L.100
Tag: C-His. Modification: unmodified. Start Site: Val131. End Site: Gly320. Coverage: 0.18. Isoelectric Point: 9. Core Sequence: VKDPEVQDFR RNILNVCKEA VDLRDLNSPH SRAMYVYPPN VESSPELPKH IYNKLDKGQI IVVIWVIVSP NNDKQKYTLK INHDCVPEQV IAEAIRKKTR SMLLSSEQLK LCVLEYQGKY ILKVCGCDEY FLEKYPLSQY KYIRSCIMLG RMPNLMLMAK ESLYSQLPMD...
| Schlagworte: | PIK3CA, Phosphoinositide 3-kinase alpha, Serine/threonine protein kinase PIK3CA, Phosphoinositide-3-kinase catalytic alpha... |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 24.5 kD |
ab 115,00 €
PIK3CA Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-04056-100ug
Description: PIK3CA Protein, Human, Recombinant (His) is expressed in E. coli with N-6xHis. The accession number is P42336.
| Schlagworte: | Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha (PtdIns-3-kinase subunit... |
| MW: | 33.9 kD |
ab 93,00 €
GDC0084
Artikelnummer: TGM-T3705-100mg
Description: GDC0084 (RG7666) is a PI3K inhibitor with potential antineoplastic activity. GDC0084 (RG7666) specifically inhibits PI3K in the PI3K/AKT kinase (or protein kinase B) signaling pathway, thereby inhibiting the activation of the PI3K signaling pathway. This may result in the inhibition of both cell growth...
| Schlagworte: | GDC-0084, RG7666, GDC 0084 |
| Anwendung: | Targets phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta |
| CAS | 1382979-44-3 |
| MW: | 382.42 D |
ab 35,00 €