Zu "K00910" wurden 119 Artikel gefunden!
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Anti-Recombinant GRK2, clone A240
Artikelnummer: E-AN301541L.100
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a...
| Schlagworte: | Anti-GRK2, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled receptor kinase 2, Recombinant GRK2 Monoclonal... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
GSK270822A
Artikelnummer: Cay43717-1
GSK270822A is an inhibitor of G protein-coupled receptor kinase 2 (GRK2, IC50 = 12. µM). It is selective for GRK2 over GRK1, GRK5, and PKA (IC50s = 794, 63. and 50. µM, respectively). InChI:...
| Schlagworte: | 1,4,5,6-tetrahydro-N-1H-indazol-5-yl-2-methyl-4-(2-naphthalenyl)-6-oxo-3-pyridinecarboxamide |
| Anwendung: | GRK2 inhibitor |
| CAS | 864082-23-5 |
| MW: | 396.45 D |
ab 147,00 €
CMPD101
Artikelnummer: Cay26808-1
CMPD101 is an inhibitor of G protein-coupled receptor kinase 2 (GRK2) and GRK3 (IC50s = 18 and 5.4 nM, respectively). It is selective for GRK2 and GRK3 over GRK1, GRK5, GRK6, and GRK7 (IC50s = 3,100, 2,300, >30,000, and 25,000 nM, respectively), as well as Rho-associated kinase 2 (ROCK2) and PKCalpha (IC50s = 1,400...
| Schlagworte: | 3-[[[4-methyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]methyl]amino]-N-[[2-(trifluoromethyl)phenyl]methyl]-benzamide |
| Anwendung: | GRK2 inhibitor, GRK3 inhibitor |
| CAS | 865608-11-3 |
| MW: | 466.5 D |
ab 50,00 €
betaARK1 Inhibitor
Artikelnummer: Cay21751-5
betaARK1 inhibitor is an inhibitor of G protein-coupled receptor kinase 2/beta-adrenergic receptor kinase 1 (GRK2/betaARK1, IC50 = 126 µM). It is selective for GRK2/betaARK1 over PKA at concentrations up to 1 mM. betaARK1 inhibitor decreases systolic blood pressure in ob/ob and nicotinamide plus...
| Schlagworte: | 5-[2-(5-nitro-2-furanyl)ethenyl]-2-furancarboxylic acid, methyl ester |
| Anwendung: | GRK2 inhibitor |
| CAS | 24269-96-3 |
| MW: | 263.2 D |
ab 56,00 €
CMPD101
Artikelnummer: TGM-T14989-1mg
Description: CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM). Which can be used for the study of heart failure. CMPD101 exhibits less selectively against GRK1, GRK5, ROCK-2 and PKCalpha with IC50s of 3.1 µM , 2.3 µM, 1.4 µM and 8.1 µM, respectively. Target: PKC, ROCK,...
| Anwendung: | GRK2 inhibitor, GRK3 inhibitor |
| CAS | 865608-11-3 |
| MW: | 466.46 D |
ab 40,00 €
Anti-ADRBK2
Artikelnummer: ARG57314.100
Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors. [The UniProt Consortium]
| Schlagworte: | Anti-ADRBK2, Anti-Beta-ARK-2, EC=2.7.11.15, Anti-Beta-adrenergic receptor kinase 2, Anti-G-protein-coupled receptor kinase 3 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Anti-BARK1 / GRK2, Internal
Artikelnummer: ARG63946.100
Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes...
| Schlagworte: | Anti-BARK, Anti-ADRBK1, Anti-Beta-ARK-1, EC=2.7.11.15, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-GRK3 / ADRBK2
Artikelnummer: NSJ-R32079
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Beta-adrenergic receptor kinase 2 (beta-ARK-2), also known as G-protein-coupled receptor kinase 3 (GRK3), is an enzyme that in humans is encoded by the ADRBK2 gene. The human ADRBK2 gene is located on 22q11. The beta-adrenergic receptor kinase specifically...
| Schlagworte: | Anti-BARK2, Anti-ADRBK2, Anti-Beta-ARK-2, EC=2.7.11.15, Anti-Beta-adrenergic receptor kinase 2, Anti-G-protein-coupled... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-GRK2
Artikelnummer: NSJ-R35552-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: ADRBK1,, adrenergic, beta, receptor kinase 1, BARK1 Protein function: Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably...
| Schlagworte: | Anti-BARK, Anti-ADRBK1, Anti-Beta-ARK-1, EC=2.7.11.15, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-ADRBK2
Artikelnummer: E-AB-10892.120
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain...
| Schlagworte: | Anti-ADRBK2, Anti-Beta-ARK-2, EC=2.7.11.15, Anti-Beta-adrenergic receptor kinase 2, Anti-G-protein-coupled receptor kinase... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-ADRBK1
Artikelnummer: E-AB-15703.120
The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related...
| Schlagworte: | Anti-ADRBK1, Anti-Beta-ARK-1, EC=2.7.11.15, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled receptor kinase... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-GRK2
Artikelnummer: 600-101-MH5
This affinity purified antibody is directed against human GRK2. This product was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis of the sequence shows 100% reactivity to human, and 90% to rat, mouse, and golden hamster. Protein function: Specifically phosphorylates the...
| Schlagworte: | Anti-ADRBK1, Anti-Beta-ARK-1, Anti-Beta-adrenergic receptor kinase 1, Anti-G-protein coupled receptor kinase 2 |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
733,00 €