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CCG215022
Artikelnummer: TGM-T3498-100mg
Description: CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 µM for GRK2, 0.38±0.06 µM for GRK5, and 3.9±1 µM for GRK1. Target: PKA, GRK. Smiles: CC1=C(C(NC(=O)N1)c1ccc(F)c(c1)C(=O)NCc1ccccn1)C(=O)Nc1ccc2[nH]ncc2c1. References: Homan KT, et al. Crystal Structure of G...
| Anwendung: | GRK inhibitor |
| CAS | 1813527-81-9 |
| MW: | 499.5 D |
ab 97,00 €
Anti-GRK1
Artikelnummer: CSB-PA002814.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-RK, Anti-RHOK, Anti-Rhodopsin kinase GRK1, Anti-G protein-coupled receptor kinase 1, EC=2.7.11.14 antibody, G... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-GRK7
Artikelnummer: CSB-PA002829.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GRK7, Anti-GPRK7, Anti-Rhodopsin kinase GRK7, Anti-G protein-coupled receptor kinase 7, Anti-G protein-coupled... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-GRK1
Artikelnummer: CSB-PA697554.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRK1. Antigen Species: Human
| Schlagworte: | Anti-RK, Anti-RHOK, Anti-Rhodopsin kinase GRK1, Anti-G protein-coupled receptor kinase 1, EC=2.7.11.14 antibody, G... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-GRK1
Artikelnummer: CSB-PA909936.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: GRK1. Antigen Species: Human
| Schlagworte: | Anti-RK, Anti-RHOK, Anti-Rhodopsin kinase GRK1, Anti-G protein-coupled receptor kinase 1, EC=2.7.11.14 antibody, G... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-GRK1
Artikelnummer: G-CAB6497.100
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
448,00 €
GRK7, GST-tag
Artikelnummer: BPS-40108
Human GRK7, also known as GPRK7 (GenBank Accession No. NM_139209), full length, with N-terminal GST tag, MW ~89 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | GRK7, GPRK7, Rhodopsin kinase GRK7, G protein-coupled receptor kinase 7, G protein-coupled receptor kinase GRK7, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 89 kD |
901,00 €
Anti-GRK1
Artikelnummer: E-AB-12493.120
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness...
| Schlagworte: | Anti-RK, Anti-RHOK, Anti-Rhodopsin kinase, Anti-G protein-coupled receptor kinase 1, GRK1 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-GRK1
Artikelnummer: E-AB-15702.120
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness...
| Schlagworte: | Anti-RK, Anti-RHOK, Anti-Rhodopsin kinase, Anti-G protein-coupled receptor kinase 1, GRK1 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-GRK1
Artikelnummer: E-AB-60810.120
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness...
| Schlagworte: | Anti-RK, Anti-RHOK, Anti-Rhodopsin kinase, Anti-G protein-coupled receptor kinase 1, GRK1 Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 243,00 €
CCG-215022
Artikelnummer: Cay31120-1
CCG-215022 is a G protein-coupled receptor kinase (GRK) inhibitor (IC50s = 3.9, 0.15, and 0.38 µM for GRK1, GRK2, and GRK5, respectively). It is selective for GRKs over protein kinase A (PKA, IC50 = 120 µM). CCG-215022 (500 nM) increases contractility in isoproterenol-stimulated isolated mouse cardiomyocytes. It...
| Schlagworte: | 4-[4-fluoro-3-[[(2-pyridinylmethyl)amino]carbonyl]phenyl]-1,2,3,4-tetrahydro-N-1H-indazol-5-yl-6-methyl-2-oxo-5-pyrimidine... |
| Anwendung: | GRK inhibitor |
| CAS | 1813527-81-9 |
| MW: | 499.5 D |
ab 61,00 €
GRK1 (Phospho-Ser21) Colorimetric Cell-Based ELISA Kit
Artikelnummer: G-CBCAB01427.96
GRK1 (Phospho-Ser21) Colorimetric Cell-Based ELISA Kit Protein function: Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade (PubMed:15946941). This rapid desensitization is essential for scotopic...
| Schlagworte: | RK, RHOK, Rhodopsin kinase GRK1, G protein-coupled receptor kinase 1 |
| Anwendung: | In-cell ELISA |
1.027,00 €