Zu "K00901" wurden 161 Artikel gefunden!
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Anti-Diacylglycerol kinase zeta / DGKZ
Artikelnummer: NSJ-F54960-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. DGKZ belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Protein function: Diacylglycerol kinase that converts diacylglycerol/DAG...
| Schlagworte: | Anti-DAGK6, Anti-DGK-zeta, Anti-DAG kinase zeta, Anti-Diglyceride kinase zeta, Anti-Diacylglycerol kinase zeta,... |
| Anwendung: | IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €
BMS 502
Artikelnummer: Cay39303-1
BMS 502 is an inhibitor of diacylglycerol kinase alpha (DGK-alpha), DGK-zeta, and DGK-iota (IC50s = 0.0046, 0.0021, and 0.0026 µM, respectively). It is selective for these DGKs over DGK-beta, DGK-gamma, and DGK-kappa (IC50s = 1, 0.68, and 4.6 µM, respectively). BMS 502 increases levels of IFN-gamma and...
| Schlagworte: | 8-[4-[bis(4-fluorophenyl)methyl]-1-piperazinyl]-5,6-dihydro-5-methyl-7-nitro-6-oxo-1,5-naphthyridine-2-carbonitrile |
| Anwendung: | DGK-alpha/DGK-zeta/DGK-iota inhibitor |
| CAS | 2407854-18-4 |
| MW: | 516.5 D |
ab 35,00 €
Dioctanoyl Glycol
Artikelnummer: Cay31515-10
Dioctanoyl glycol is a diacylglycerol kinase (DGK) inhibitor (Ki = 58 µM). It reduces basal and thrombin-stimulated phosphatidic acid levels in washed isolated human platelets when used at concentrations of 30, 100, and 500 µM.Formal Name: octanoic acid, 1,1'-(1,2-ethanediyl) ester. CAS Number: 627-86-1. Synonyms:...
| Schlagworte: | 8:0 Ethylene Glycol, diC8-Ethylene Glycol, Dioctanoyl Glycol, Ethylene Glycol Dioctanoate, NSC 97300, octanoic acid,... |
| Anwendung: | DGK inhibitor |
| CAS | 627-86-1 |
| MW: | 314.5 D |
ab 40,00 €
R-59-022
Artikelnummer: Cay16772-1
Diacylglycerol (DAG) kinases (DGKs) phosphorylate DAG to give phosphatidic acid (PA), reducing signaling through DAG and increasing signaling through PA. R-59-022 is an inhibitor of DGK (IC50 = 2.8 µM). This results in increased DAG-dependent PKC activity and potentiates aggregation of thrombin-stimulated platelets....
| Schlagworte: | Diacylglycerol Kinase Inhibitor I,... |
| Anwendung: | Diacylglycerol kinase inhibitor |
| CAS | 93076-89-2 |
| MW: | 459.6 D |
ab 50,00 €
R-59-949
Artikelnummer: Cay21221-5
R-59-949 is an inhibitor of diacylglycerol kinase alpha (DGK-alpha) with an IC50 value of 300 nM in isolated platelet plasma membranes using exogenous diacylglycerol as a substrate. DGK-alpha inhibition with R-59-949 increases diacylglycerol-dependent PKC activity, serotonin secretion, and aggregation of...
| Schlagworte: | Diacylglycerol Kinase Inhibitor II, DKGI-II,... |
| Anwendung: | DGK inhibitor |
| CAS | 120166-69-0 |
| MW: | 489.6 D |
ab 43,00 €
Anti-DGKzeta
Artikelnummer: A302-967A
Protein function: Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. [The UniProt Consortium]
| Schlagworte: | Anti-DGKZ, Anti-DAGK6, Anti-DGK-zeta, EC=2.7.1.107, Anti-DAG kinase zeta, Anti-Diglyceride kinase zeta,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Cochlioquinone A
Artikelnummer: Cay19440-2.5
Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK, Ki = 3.1 µM) and diacylglycerol acyltransferase (DGAT, IC50 = 5.6 µM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 µM....
| Schlagworte: | (3R,4aR,6aR,12S,12aS,12bR)-9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy... |
| Anwendung: | DGK / DGAT inhibitor |
| CAS | 32450-25-2 |
| MW: | 532.7 D |
ab 390,00 €
Anti-DGKZ
Artikelnummer: E-AB-16203.120
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding...
| Schlagworte: | Anti-DGKZ, Anti-DAGK6, Anti-DGK-zeta, EC=2.7.1.107, Anti-DAG kinase zeta, Anti-Diglyceride kinase zeta,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-DGKB
Artikelnummer: E-AB-16209.120
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase)...
| Schlagworte: | Anti-DGKB, Anti-DAGK2, Anti-DGK-beta, EC=2.7.1.107, Anti-DAG kinase beta, Anti-Diglyceride kinase beta,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-DGKA
Artikelnummer: ARG58472.100
Protein function: Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. [The UniProt Consortium]
| Schlagworte: | Anti-DAGK, Anti-DGKA, Anti-DGK-alpha, EC=2.7.1.107, Anti-DAG kinase alpha, Anti-Diglyceride kinase alpha,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-DGKA
Artikelnummer: ARG58543.100
Protein function: Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. [The UniProt Consortium]
| Schlagworte: | Anti-DAGK, Anti-DGKA, Anti-DGK-alpha, EC=2.7.1.107, Anti-DAG kinase alpha, Anti-Diglyceride kinase alpha,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
584,00 €
Anti-DGKE
Artikelnummer: E-AB-65558.120
Diacylglycerol kinases are thought to be involved mainly in the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction. When expressed in mammalian cells, DGK-epsilon shows specificity for arachidonyl-containing diacylglycerol. DGK-epsilon is expressed...
| Schlagworte: | Anti-DGKE, Anti-DAGK5, Anti-DGK-epsilon, EC=2.7.1.107, Anti-DAG kinase epsilon, Anti-Diglyceride kinase epsilon,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 198,00 €