Zu "K00901" wurden 208 Artikel gefunden!
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R-59-022
Artikelnummer: Cay16772-1
Diacylglycerol (DAG) kinases (DGKs) phosphorylate DAG to give phosphatidic acid (PA), reducing signaling through DAG and increasing signaling through PA. R-59-022 is an inhibitor of DGK (IC50 = 2.8 µM). This results in increased DAG-dependent PKC activity and potentiates aggregation of thrombin-stimulated platelets....
| Schlagworte: | Diacylglycerol Kinase Inhibitor I,... |
| Anwendung: | Diacylglycerol kinase inhibitor |
| CAS | 93076-89-2 |
| MW: | 459.6 D |
ab 56,00 €
R-59-949
Artikelnummer: Cay21221-5
R-59-949 is an inhibitor of diacylglycerol kinase alpha (DGK-alpha) with an IC50 value of 300 nM in isolated platelet plasma membranes using exogenous diacylglycerol as a substrate. DGK-alpha inhibition with R-59-949 increases diacylglycerol-dependent PKC activity, serotonin secretion, and aggregation of...
| Schlagworte: | Diacylglycerol Kinase Inhibitor II, DKGI-II,... |
| Anwendung: | DGK inhibitor |
| CAS | 120166-69-0 |
| MW: | 489.6 D |
ab 49,00 €
R59949
Artikelnummer: TGM-T26019-1mg
Description: R59949 is used as a Diacylglycerol kinase (DGK) inhibitor. Target: PKC. Smiles: Fc1ccc(cc1)C(=C1CCN(CCn2c(=S)[nH]c3ccccc3c2=O)CC1)c1ccc(F)cc1
| Schlagworte: | R-59949 , R 59949 |
| Anwendung: | DGK inhibitor |
| CAS | 120166-69-0 |
| MW: | 489.58 D |
ab 38,00 €
Anti-DGKzeta
Artikelnummer: A302-967A
Protein function: Displays a strong preference for 1,2-diacylglycerols over 1,3-diacylglycerols, but lacks substrate specificity among molecular species of long chain diacylglycerols. Isoform 2 but not isoform 1 regulates RASGRP1 activity. [The UniProt Consortium]
| Schlagworte: | Anti-DGKZ, Anti-DAGK6, Anti-DGK-zeta, EC=2.7.1.107, Anti-DAG kinase zeta, Anti-Diglyceride kinase zeta,... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Cochlioquinone A
Artikelnummer: Cay19440-2.5
Cochlioquinone A, a bioactive compound isolated from D. sacchari and Bipolaris sp., is an inhibitor of diacylglycerol kinase (DGK, Ki = 3.1 µM) and diacylglycerol acyltransferase (DGAT, IC50 = 5.6 µM). It has been shown to reduce the concentration of phosphatidic acid in T cell lymphoma with an IC50 value of 3 µM....
| Schlagworte: | (3R,4aR,6aR,12S,12aS,12bR)-9-[(1S,2R,3S)-2-(acetyloxy)-1,3-dimethylpentyl]-1,2,3,4a,5,6,6a,12,12a,12b-decahydro-12-hydroxy... |
| Anwendung: | DGK / DGAT inhibitor |
| CAS | 32450-25-2 |
| MW: | 532.7 D |
ab 423,00 €
Anti-DGKZ
Artikelnummer: E-AB-16203.120
The protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It may attenuate protein kinase C activity by regulating diacylglycerol levels in intracellular signaling cascade and signal transduction. Alternative splicing occurs at this locus and multiple transcript variants encoding...
| Schlagworte: | Anti-DGKZ, Anti-DAGK6, Anti-DGK-zeta, EC=2.7.1.107, Anti-DAG kinase zeta, Anti-Diglyceride kinase zeta,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-DGKB
Artikelnummer: E-AB-16209.120
Diacylglycerol kinases (DGKs) are regulators of the intracellular concentration of the second messenger diacylglycerol (DAG) and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic (kinase)...
| Schlagworte: | Anti-DGKB, Anti-DAGK2, Anti-DGK-beta, EC=2.7.1.107, Anti-DAG kinase beta, Anti-Diglyceride kinase beta,... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-DGKA
Artikelnummer: ARG58472.100
Protein function: Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. [The UniProt Consortium]
| Schlagworte: | Anti-DAGK, Anti-DGKA, Anti-DGK-alpha, EC=2.7.1.107, Anti-DAG kinase alpha, Anti-Diglyceride kinase alpha,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Anti-DGKA
Artikelnummer: ARG58543.100
Protein function: Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity. [The UniProt Consortium]
| Schlagworte: | Anti-DAGK, Anti-DGKA, Anti-DGK-alpha, EC=2.7.1.107, Anti-DAG kinase alpha, Anti-Diglyceride kinase alpha,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-DGKI
Artikelnummer: E-AB-17825.120
This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role...
| Schlagworte: | Anti-DGKI, Anti-DGK-iota, EC=2.7.1.107, Anti-DAG kinase iota, Anti-Diglyceride kinase iota, Anti-Diacylglycerol kinase... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-DGKI
Artikelnummer: E-AB-19733.120
This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role...
| Schlagworte: | Anti-DGKI, Anti-DGK-iota, EC=2.7.1.107, Anti-DAG kinase iota, Anti-Diglyceride kinase iota, Anti-Diacylglycerol kinase... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
DGKalpha, His-Avi-Tag, Biotin-Labeled
Artikelnummer: BPS-100964
Recombinant human DGKA (diacylglycerol kinase alpha, variant 3), encompassing amino acids 2-735 (end). This construct contains a N-terminal His-tag (6xHis) followed by an Avi-Tag(TM). The recombinant protein was enzymatically biotinylated using the Avi-Tag(TM) and affinity purified.
| Schlagworte: | DGKA, DAGK, DGK-alpha, DAG kinase alpha, Diglyceride kinase alpha, Diacylglycerol kinase alpha, 80 kDa diacylglycerol... |
| Anwendung: | Kinase studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 85 kD |
663,00 €