Zu "K00888" wurden 18 Artikel gefunden!
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Human PI4Ka (Phosphatidylinositol-4-Kinase Catalytic...
Artikelnummer: ELK-ELK5139.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PI4Ka. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PI4Ka. Next,...
| Schlagworte: | PIK4, PI4KA, PI4K-alpha, PI4-kinase alpha, PtdIns-4-kinase alpha, Phosphatidylinositol 4-kinase alpha,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
GSK-F1
Artikelnummer: SYN-1220-M001
Solid. Soluble in DMSO. GSK-F1 is a potent PI4KA inhibitor. It has better pharmacokinetic properties in vivo than to GSK-A1 (SYN-1219). GSK-F1 does not cross the blood-brain barrier. Phosphatidylinositol 4-kinase type III? (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for...
| Schlagworte: | 5-(2-Amino-4-oxo-3-(2-(trifluoromethyl)phenyl)-3,4-dihydroquinazolin-6-yl)-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulf... |
| Anwendung: | Potent PI4KA inhibitor |
| CAS | 1402345-92-9 |
| MW: | 603,5 D |
ab 158,00 €
GSK-A1
Artikelnummer: SYN-1219-M001
Solid. Soluble in DMSO. GSK-A1 is a potent PI4KA inhibitor with an IC50 of about 3nM in vitro using HEK-AT1 cells. Phosphatidylinositol 4-kinase type III? (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory...
| Schlagworte: | 5-(2-Amino-1-(4-morpholinophenyl)-1H-benzo[d]imidazol-6-yl)-N-(2-fluorophenyl)-2-methoxypyridine-3-sulfonamide, GSKA1 |
| Anwendung: | Potent PI4KA inhibitor |
| CAS | 1416334-69-4 |
| MW: | 574,6 D |
ab 158,00 €
GSK-A1
Artikelnummer: Cay34502-1
GSK-A1 is an inhibitor of phosphatidylinositol 4-kinase IIIalpha (PI4KIIIalpha, IC50 = 3.16 nM). It is selective for PI4KIIIalpha over PI4KIIIbeta, PI3Kalpha, PI3Kbeta, and PI3Kdelta (IC50s = >50 nM) but also inhibits PI3Kgamma (IC50 = 15.8 nM). GSK-A1 decreases the levels of phosphatidylinositol 4-phosphate...
| Schlagworte: | 5-[2-amino-1-[4-(4-morpholinyl)phenyl]-1H-benzimidazol-6-yl]-N-(2-fluorophenyl)-2-methoxy-3-pyridinesulfonamide |
| Anwendung: | PI4KIIIalpha inhibitor |
| CAS | 1416334-69-4 |
| MW: | 574.6 D |
ab 40,00 €
PIK-93
Artikelnummer: LKT-P3542.1
PIK93 is an inhibitor of PI3K that exhibits some selectivity for p110 and p110 . PIK93 also inhibits PI4KIII , a phosphatidylinositol enzyme similar to PI3K. PIK93 decreases translocation of transient receptor potential canonical 6 channel (TRPC6) to the plasma membrane in vitro and may alter Ca2+ signaling as a...
| Schlagworte: | PIK93 |
| Anwendung: | PI4KB inhibitor |
| CAS | 593960-11-3 |
| MW: | 389.88 D |
ab 205,00 €
PIK-93
Artikelnummer: SYN-1066-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. PIK-93 selectively inhibits the type III PI 4-kinase beta enzyme (IC(50) of 19nM). It has also been shown to have activity on PI3Kalpha with an IC(50) of 39nM. Target: PI3K , Kinase Group: Lipid Kinase , Substrate: Lipid
| Schlagworte: | PIK93 |
| Anwendung: | PI4KB inhibitor |
| CAS | 593960-11-3 |
| MW: | 389,9 D |
ab 139,00 €
BQR-695
Artikelnummer: Cay27482-1
BQR-695 is an antimalarial compound. It inhibits recombinant P. vivax and human phosphatidylinositol 4-kinase (PI4K, IC50s = 3.5 and 90 nM, respectively). BQR-695 induces schizont-stage arrest and death of P. falciparum (IC50 = ~70 nM) without inducing cytotoxicity in mature red blood cells (RBCs).Formal Name:...
| Schlagworte: | 2-[[7-(3,4-dimethoxyphenyl)-2-quinoxalinyl]amino]-N-methyl-acetamide |
| Anwendung: | Antimalarial compound, Phosphatidylinositol 4-kinase inhibitor |
| CAS | 1513879-21-4 |
| MW: | 352.4 D |
ab 50,00 €
Anti-PI4KA
Artikelnummer: G-CAB19329.100
Protein function: Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate. [The UniProt Consortium]
| Schlagworte: | Anti-PIK4, Anti-PI4KA, Anti-PI4K-alpha, Anti-PI4-kinase alpha, Anti-PtdIns-4-kinase alpha, Anti-Phosphatidylinositol... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €
Anti-PI4KA
Artikelnummer: ATA-HPA075515.100
Protein function: Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol-1,4,5,- trisphosphate. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100%...
| Schlagworte: | Anti-PIK4, Anti-PI4KA, Anti-PI4K-alpha, Anti-PI4-kinase alpha, Anti-PtdIns-4-kinase alpha, Anti-Phosphatidylinositol... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 335,00 €
Anti-PI4KA
Artikelnummer: E-AB-92153.120
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The...
| Schlagworte: | PIK4, PI4KA, PI4K-alpha, PI4-kinase alpha, PtdIns-4-kinase alpha, Phosphatidylinositol 4-kinase alpha,... |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-PI4KA
Artikelnummer: ELK-ES14116.100
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The...
| Schlagworte: | Anti-PIK4, Anti-PI4KA, Anti-PI4K-alpha, Anti-PI4-kinase alpha, Anti-PtdIns-4-kinase alpha, Anti-Phosphatidylinositol... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €
PIK4CA, Human, Real Time PCR Primer Set
Artikelnummer: VHPS-6894
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | PIK4, PI4KA, PI4K-alpha, EC=2.7.1.67, PI4-kinase alpha, PtdIns-4-kinase alpha, Phosphatidylinositol 4-kinase alpha |
| Anwendung: | RNA quantification |
43,00 €