Zu "K00844" wurden 132 Artikel gefunden!
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2-deoxy-D-Glucose
Artikelnummer: Cay14325-1
2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis. It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate. 2-deoxy-D-glucose (16 mM) induces apoptosis in...
| Schlagworte: | Ba 2758, NSC 15193, 2-deoxy-D-arabino-hexose |
| Anwendung: | Non-metabolizable glucose analog |
| CAS | 154-17-6 |
| MW: | 164.2 D |
ab 68,00 €
C-02
Artikelnummer: Cay39384-1
C-02 is a proteolysis-targeting chimera (PROTAC) composed of the hexokinase inhibitor lonidamine (Cay-14640) linked to the cereblon ligand thalidomide (Cay-14610). It induces degradation of hexokinase 2 in 786-O and PANC-1 cells when used at a concentration of 20 µM. C-02 is cytotoxic to 786-O, 4T1, PANC-1, HGC-27,...
| Schlagworte: | 1-(2,4-dichlorobenzyl)-N-(4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)butyl)-1H-indazole-3-carboxamide |
| Anwendung: | PROTAC, hexokinase 2 degradation |
| MW: | 647.5 D |
ab 36,00 €
Mouse HK2 (Hexokinase 2) ELISA Kit
Artikelnummer: ELK-ELK7586.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HK2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HK2. Next,...
| Schlagworte: | HK II, Hexokinase-2, Hexokinase type II |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human HK2 (Hexokinase 2) ELISA Kit
Artikelnummer: ELK-ELK3465.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HK2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HK2. Next,...
| Schlagworte: | HK II, Hexokinase-B, Hexokinase-2, Hexokinase type II, Muscle form hexokinase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Pig HK2 (Hexokinase 2) ELISA Kit
Artikelnummer: ELK-ELK8578.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Pig HK2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Pig HK2. Next, Avidin...
| Schlagworte: | HK II, Hexokinase-2, Hexokinase type II |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | swine |
ab 365,00 €
Human HK1 (Hexokinase 1) ELISA Kit
Artikelnummer: ELK-ELK1711.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HK1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HK1. Next,...
| Schlagworte: | HK I, Hexokinase-A, Hexokinase-1, Hexokinase type I, Brain form hexokinase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
D-Glucose-6-phosphate (sodium salt)
Artikelnummer: Cay20376-1
D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis. It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate...
| Schlagworte: | G6P, Sodium Glucose-6-Phosphate, D-glucose-6-(dihydrogen phosphate), monosodium salt |
| Anwendung: | Glycolysis / pentose phosphate pathway / glycogen synthesis starting molecule |
| CAS | 54010-71-8 |
| MW: | 282.1 D |
ab 43,00 €
Lonidamine
Artikelnummer: Cay14640-10
Lonidamine, originally identified as a potent antispermatogenic agent, inhibits glycolysis though the inactivation of mitochondria-bound hexokinase. It can decrease oxygen consumption as well as aerobic and anaerobic glycolysis in Ehrlich ascites tumor cells with IC50 values of 90 and 45 µM, respectively. A role for...
| Schlagworte: | AF 1890, DICA, Diclondazolic Acid, 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid |
| Anwendung: | Anticancer agent, HK1 inhibitor |
| CAS | 50264-69-2 |
| MW: | 321.2 D |
ab 66,00 €
2-deoxy-D-Glucose-13C6
Artikelnummer: Cay34312-10
2-deoxy-D-Glucose-13C6 is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose (Cay-14325) by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis. It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as...
| Schlagworte: | 2-DG-13C6, (4R,5S,6R)-6-(hydroxymethyl-13C)tetrahydro-2H-pyran-2,4,5-triol-2,3,4,5,6-13C5 |
| Anwendung: | GC-MS, LC-MS internal standard, Quantification, Non-metabolizable glucose analog |
| MW: | 170.1 D |
ab 98,00 €
D-Mannoheptulose
Artikelnummer: AG-CR1-3695-M005
Naturally occurring heptose in avocado fruit. Hexokinase (HK) and glucokinase inhibitor in diverse organisms by competing with D-glucose. Useful agent for immunometabolism research. Blocks glucose phosphorylation by blocking hexokinase. Prevents the conversion of glucose to glucose-6-phosphate that can mediate the...
| Schlagworte: | D-Manno-2-heptulose, NSC 226836 |
| Anwendung: | Hexokinase (HK) / glucokinase inhibitor |
| CAS | 3615-44-9 |
| MW: | 210.2 D |
ab 55,00 €
Anti-Hexokinase 1, clone 6B8-G11-E7
Artikelnummer: ARG54058.100
| Schlagworte: | Anti-HK1, Anti-HK I, EC=2.7.1.1, Anti-Hexokinase-1, Anti-Hexokinase type I, Anti-Brain form hexokinase |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-Hexokinase II
Artikelnummer: ARG55103.100
| Schlagworte: | Anti-HK2, Anti-HK II, EC=2.7.1.1, Anti-Hexokinase-2, Anti-Hexokinase type II, Anti-Muscle form hexokinase |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
624,00 €