Zu "K00801" wurden 29 Artikel gefunden!
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Zaragozic Acid A
Artikelnummer: Cay17452-1
Squalene synthase catalyzes the first committed step in cholesterol synthesis, mediating the reductive dimerization of farnesyl pyrophosphate (Cay-63250) to produce squalene. Zaragozic acid A is a fungal metabolite that acts as a reversible competitive inhibitor of squalene synthase (Ki = 78 pM in vitro). It...
| Schlagworte: | L-694,599, Squalestatin S1, (7S)-11-acetate... |
| Anwendung: | Reversible competitive squalene synthase inhibitor |
| CAS | 142561-96-4 |
| MW: | 690.7 D |
ab 261,00 €
YM-53601
Artikelnummer: Cay18113-500
YM-53601 is a squalene synthase inhibitor (IC50s = 79 and 90 nM in HepG2 cells and rat liver microsomes, respectively). It inhibits cholesterol biosynthesis in rats (ED50 = 32 mg/kg). YM-53601 dose-dependently reduces plasma triglyceride and non-HDL cholesterol levels in hamsters fed both normal and high-fat diets....
| Schlagworte: | 2-[(2E)-2-(1-azabicyclo[2.2.2]oct-3-ylidene)-2-fluoroethoxy]-9H-carbazole, monohydrochloride |
| Anwendung: | Squalene synthase inhibitor |
| CAS | 182959-33-7 |
| MW: | 372.9 D |
ab 278,00 €
Mouse Somatostatin ELISA Kit
Artikelnummer: G-MOFI00257.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Squalene
Artikelnummer: Cay27058-50
Squalene is a biosynthetic precursor to all steroids and a terpene originally isolated from shark liver oil. Squalene is produced in mammals by condensation of two farnesyl diphosphate molecules by squalene synthase and then oxidized to squalene epoxide for use in the biosynthesis of lanosterol (Cay-19521),...
| Schlagworte: | trans-Squalene, Spinacene, (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene |
| Anwendung: | Biosynthetic steroid precursor |
| CAS | 111-02-4 |
| MW: | 410.7 D |
ab 43,00 €
Anti-FDFT1
Artikelnummer: ARG55581.100
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
584,00 €
Anti-FDFT1
Artikelnummer: ARG65709.100
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-FDFT1
Artikelnummer: A305-361A
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-FDFT1
Artikelnummer: A305-409A
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-FDFT1
Artikelnummer: E-AB-61840.120
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 198,00 €
Anti-FDFT1
Artikelnummer: E-AB-19026.120
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-FDFT1
Artikelnummer: E-AB-52940.120
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, EC=2.5.1.21, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-SQS/FDFT1
Artikelnummer: G-CAB4651.100
Protein function: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of...
| Schlagworte: | Anti-SS, Anti-SQS, Anti-FDFT1, Anti-Squalene synthase, Anti-FPP:FPP farnesyltransferase, Anti-Farnesyl-diphosphate... |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 352,00 €