Zu "K00796" wurden 52 Artikel gefunden!
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Sulfamethoxazole
Artikelnummer: Cay23613-25
Sulfamethoxazole is a sulfonamide antibiotic. It inhibits growth of E. coli (MIC = 10 µg/ml) and clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 25-50 µg/ml). Sulfamethoxazole, in combination with trimethoprim (Cay-16473) at a ratio of 20:1, inhibits growth of MRSA in vivo in mice (MIC = 0.8...
| Schlagworte: | NSC 147832, Ro 4-2130, 4-amino-N-(5-methyl-3-isoxazolyl)-benzenesulfonamide |
| Anwendung: | Antibacterial, folic acid biosynthesis inhibitor |
| CAS | 723-46-6 |
| MW: | 253.3 D |
ab 56,00 €
Sulfamethazine
Artikelnummer: Cay20976-25
Sulfamethazine is a sulfonamide antibiotic. It inhibits dihydropteroate synthase (DHPS, IC50 = 5.7 µM for the T. gondii enzyme). Sulfamethazine is active against A. pleuropneumoniae (MIC = 32 µg/ml) and enhances the antibacterial activity of trimethoprim (Cay-16473) against E. coli. It has been detected in...
| Schlagworte: | NSC 67457, NSC 683529, Sulfadimethyldiazine, Sulfadimidine, 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-benzenesulfonamide |
| Anwendung: | Antibacterial sulfonamide, dihydropteroate synthase inhibitor |
| CAS | 57-68-1 |
| MW: | 278.3 D |
ab 30,00 €
Sulfamethoxazole-d4
Artikelnummer: Cay28618-1
Sulfamethoxazole-d4 is intended for use as an internal standard for the quantification of sulfamethoxazole (Cay-23613) by GC- or LC-MS. Sulfamethoxazole is a sulfonamide antibiotic. It inhibits growth of E. coli (MIC = 10 µg/ml) and clinical isolates of methicillin-resistant S. aureus (MRSA, MICs = 25-50 µg/ml)....
| Schlagworte: | 4-amino-N-(5-methyl-3-isoxazolyl)-benzene-2,3,5,6-d4-sulfonamide |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, antibacterial, folic acid biosynthesis inhibitor |
| CAS | 1020719-86-1 |
| MW: | 257.3 D |
ab 88,00 €
Sulfacetamide (sodium salt)
Artikelnummer: Cay20377-100
Sulfacetamide is a sulfonamide antibiotic that is bacteriostatic against Gram-positive and Gram-negative bacteria. It inhibits dihydropteroate synthase (IC50 = 9.6 µM), blocking the synthesis of dihydrofolic acid, and also inhibits bacterial 4-aminobenzoic acid (Cay-18659), which is required for the synthesis of...
| Schlagworte: | N-acetyl Sulfanilamide, N-[(4-aminophenyl)sulfonyl]-acetamide, monosodium salt |
| Anwendung: | Antibacterial, folic acid biosynthesis inhibitor |
| CAS | 127-56-0 |
| MW: | 236.2 D |
ab 49,00 €
Sulfamethoxazole hydroxylamine
Artikelnummer: CDX-S0056-M010
Off-white powder. Soluble in methanol or DMSO. Sligthly soluble in water. Metabolite of sulfamethoxazole, a sulfonamide bacteriostatic antibiotic. Has been shown to be an important component in sulfonamide hypersensitivity reactions and has been implicated in sulfonamide-mediated immunomodulatory effects. Shown to...
| Schlagworte: | Sulfamethoxazole N4-hydroxylamine, SMX-HA, SMX-NHOH, NSC 665547, 4-(Hydroxyamino)-N-(5-methyl-3-isoxazolyl)benzenesulfonamide |
| Anwendung: | Sulfamethoxazole metabolite, Analytical reference material |
| CAS | 114438-33-4 |
| MW: | 269,28 D |
ab 244,00 €
Sulfamethoxypyridazine
Artikelnummer: Cay21875-5
Sulfamethoxypyridazine is a sulfonamide antibiotic that inhibits the growth of Gram-negative bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS, IC50 = 17 nM) and folate biosynthesis in P. carinii by 75% when used at a concentration of 50 nM. Sulfamethoxypyridazine...
| Schlagworte: | 4-amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide |
| Anwendung: | Antibacterial sulfonamide antibiotic, folic acid biosynthesis inhibitor |
| CAS | 80-35-3 |
| MW: | 280.3 D |
ab 49,00 €
Sulfameter
Artikelnummer: Cay27630-5
Sulfameter is a long-acting sulfonamide antibiotic. In vitro, it is active against the bacteria D. pneumoniae, K. pneumoniae, E. coli, N. meningitidis, P. vulgaris, S. aureus, S. haemolyticus, and S. typhimurium in a disc assay. Sulfameter is efficacious against lethal K. pneumoniae, E. coli, P. vulgaris, D....
| Schlagworte: | Bayrena, NSC 683528, Sulfamethoxydiazine, 4-amino-N-(5-methoxy-2-pyrimidinyl)-benzenesulfonamide |
| Anwendung: | Antibacterial, sulfonamide antibiotic |
| CAS | 651-06-9 |
| MW: | 280.3 D |
ab 122,00 €
Sulfadimethoxine
Artikelnummer: Cay28827-5
Sulfadimethoxine is a sulfonamide antibiotic that is active against Gram-negative and Gram-positive bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS, IC50 = 25 nM), an enzyme required for folate biosynthesis, in a cell-free assay. Sulfadimethoxine is active against...
| Schlagworte: | Sulphadimethoxine, 4-amino-N-(2,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamide |
| Anwendung: | Sulfonamide antibiotic, antibacterial, folic acid biosynthesis inhibitor |
| CAS | 122-11-2 |
| MW: | 310.3 D |
ab 49,00 €
Sulfaphenazole
Artikelnummer: TGM-T4567-100mg
Description: Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 µM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 µM for CYP2C8/CYP2C18, respectively, and no activity at CYP1A1, CYP1A2, CYP3A4, CYP2C19). At 10 µM, sulfaphenazole has been shown to inhibit...
| Schlagworte: | Raziosulfa, Depocid, Depotsulfonamide, Plisulfan |
| Anwendung: | Targets dihydropteroate synthase [EC:2.5.1.15] (folP) |
| CAS | 526-08-9 |
| MW: | 314.36 D |
ab 46,00 €
Sulfanilamide
Artikelnummer: Cay23723-10
Sulfanilamide is a sulfonamide antibiotic. It is bacteriostatic against Streptococcus when used at a concentration of 20 µg/ml and inhibits the growth of 106 clinical isolates of Gonococcus at 0.01% v/v. Sulfanilamide reduces plasma levels of Streptococcus in infected rabbits. It is an inhibitor of carbonic...
| Schlagworte: | p-Aminobenzenesulfonamide, 4-Aminobenzenesulfonamide, NSC 7618, Ro 1-3354, 4-amino-benzenesulfonamide |
| Anwendung: | Antibacterial, folic acid biosynthesis inhibitor |
| CAS | 63-74-1 |
| MW: | 172.2 D |
ab 85,00 €
Dapsone
Artikelnummer: Cay23743-100
Dapsone is an anti-inflammatory, antimalarial, and antibacterial compound. In vivo, dapsone (34 µg/animal per day) reduces epidermal hyperproliferation and epithelial thickness in the esophagus in a mouse model of proliferative dermatitis. It reduces lipid peroxidation, myeloperoxidase activity, and cellular...
| Schlagworte: | 4,4'-Diaminodiphenyl sulfone, NSC 6091, 4,4'-sulfonylbis-benzenamine |
| Anwendung: | Antibacterial (leprostatic) |
| CAS | 80-08-0 |
| MW: | 248.3 D |
ab 49,00 €
Sulfadoxin
Artikelnummer: Cay21488-10
Sulfadoxin is a sulfonamide antibiotic that inhibits dihydropteroate synthetase (DHPS), an enzyme involved in folic acid (Cay-20515) synthesis. Sulfadoxin competes with 4-aminobenzoate (PABA), the native substrate of DHPS, and inhibits PABA incorporation into folic acid. Folate is essential for purine and pyrimidine...
| Schlagworte: | Ro 4-4393, 4-amino-N-(5,6-dimethoxy-4-pyrimidinyl)-benzenesulfonamide |
| Anwendung: | Antibacterial, antimalarial, folic acid biosynthesis inhibitor |
| CAS | 2447-57-6 |
| MW: | 310.3 D |
ab 56,00 €