Zu "K00787" wurden 32 Artikel gefunden!
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Anti-FDPS (Center Region), clone 1049CT13.1.4
Artikelnummer: NSJ-F54092-0.05ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Farnesyl diphosphate synthase is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as...
| Schlagworte: | Anti-FPS, Anti-FPP synthase, Anti-Geranyltranstransferase, Anti-Farnesyl diphosphate synthase,... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Human FDPS (Farnesyl Diphosphate Synthase) ELISA Kit
Artikelnummer: ELK-ELK5063.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human FDPS. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human FDPS. Next,...
| Schlagworte: | FPS, FPP synthase, Geranyltranstransferase, Dimethylallyltranstransferase, Farnesyl diphosphate synthase, Farnesyl... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat FDPS (Farnesyl Diphosphate Synthase) ELISA Kit
Artikelnummer: ELK-ELK6950.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat FDPS. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat FDPS. Next,...
| Schlagworte: | FPS, Fdps, CR 39, EC=2.5.1.1, EC=2.5.1.10, FPP synthase, Geranyltranstransferase, Dimethylallyltranstransferase, Farnesyl... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Zoledronic Acid (hydrate)
Artikelnummer: Cay14984-25
Zoledronic acid is a third-generation heterocyclic nitrogen-containing bisphosphonate that inhibits the prenylation of GTPases critical to the signaling events related to osteoclast-mediated bone resorption. It has a high affinity for hydroxyapatite (Ki = 3.47 µM) and binds directly to mineralized bone where it...
| Schlagworte: | P,P'-[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-phosphonic acid, monohydrate |
| Anwendung: | GTPase prenylation inhibitor, Farnesylpyrophosphate synthetase inhibitor |
| CAS | 165800-06-6 |
| MW: | 290.1 D |
ab 92,00 €
Zoledronic Acid Hydrate
Artikelnummer: LKT-Z5744.10
Bisphosphonate, FPPS inhibitor.
| Schlagworte: | Zoledronate, Zometa, [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]- bisphosphonic acid |
| Anwendung: | Farnesylpyrophosphate synthetase inhibitor |
| CAS | 165800-06-6 |
| MW: | 290.1 D |
ab 121,00 €
Pamidronate (sodium salt)
Artikelnummer: Cay23699-25
Pamidronate is an amino bisphosphonate that inhibits farnesyl pyrophosphate (FPP) synthase (IC50s = 0.85 and 0.20 µM in J774 cells and for human recombinant FPP synthase, respectively). In rats, it inhibits bone resorption when used at doses of 16 µmol/kg per day, impairs long bone growth at >40 µmol/kg per day, and...
| Schlagworte: | APD, CGP 23339A, Pamidronic Acid, P,P'-(3-amino-1-hydroxypropylidene)bis-phosphonic acid, disodium salt |
| Anwendung: | Farnesylpyrophosphate synthetase inhibitor |
| CAS | 57248-88-1 |
| MW: | 279 D |
ab 68,00 €
Ibandronate (sodium hydrate)
Artikelnummer: Cay21361-25
Ibandronate is a bisphosphonate that has been used in formulations for the treatment of osteoporosis. It binds to hydroxyapatite crystals with an affinity constant of 2.36 µM, inhibiting their growth and bone resorption.Formal Name: P,P'-[1-hydroxy-3-(methylpentylamino)propylidene]bis-phosphonic acid, monosodium...
| Schlagworte: | P,P'-[1-hydroxy-3-(methylpentylamino)propylidene]bis-phosphonic acid, monosodium salt, monohydrate |
| Anwendung: | Bisphosphonate, osteoporosis agent, FDPS inhibitor |
| CAS | 138926-19-9 |
| MW: | 359.2 D |
ab 54,00 €
Anti-FDPS
Artikelnummer: A305-045A
Protein function: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation....
| Schlagworte: | Anti-FPS, Anti-FDPS, EC=2.5.1.1, EC=2.5.1.10, Anti-FPP synthase, Anti-Geranyltranstransferase,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Zoledronate Disodium
Artikelnummer: LKT-Z5645.10
Zoledronic acid is used as an antiresorptive agent in bone.
| Schlagworte: | Zoledronic acid disodium salt tetrahydrate |
| Anwendung: | Farnesylpyrophosphate synthetase inhibitor |
| CAS | 165800-07-7 |
| MW: | 390,13 D |
ab 170,00 €
Anti-FDPS
Artikelnummer: ARG41025.100
Protein function: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation....
| Schlagworte: | Anti-FPS, Anti-FDPS, EC=2.5.1.1, EC=2.5.1.10, Anti-FPP synthase, Anti-Geranyltranstransferase,... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-FDPS
Artikelnummer: E-AB-19027.120
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein...
| Schlagworte: | Anti-FPS, Anti-FDPS, EC=2.5.1.1, EC=2.5.1.10, Anti-FPP synthase, Anti-Geranyltranstransferase, Anti-Farnesyl diphosphate... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-FDPS
Artikelnummer: E-AB-52941.120
This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein...
| Schlagworte: | Anti-FPS, Anti-FDPS, EC=2.5.1.1, EC=2.5.1.10, Anti-FPP synthase, Anti-Geranyltranstransferase, Anti-Farnesyl diphosphate... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €