Suchergebnis für K00688 | Biomol GmbH

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1,4-dideoxy-1,4-imino-D-Arabinitol (hydrochloride)

Artikelnummer: Cay20939-1

1,4-dideoxy-1,4-imino-D-Arabinitol (DAB) is an inhibitor of glycogen phosphorylase, a key enzyme in glycogenolysis. It inhibits glycogenolysis in isolated liver cells (IC50 = 1.0 µM) and in homogenates of cerebral cortex and cerebellum (IC50s = 463 and 383 nM, respectively). DAB is used to inhibit glycogenolysis, in...

Schlagworte:	DAB, 2R-(hydroxymethyl)-3R,4R-pyrrolidinediol, monohydrochloride
Anwendung:	Glycogen phosphorylase inhibitor
CAS	100991-92-2
MW:	169.6 D

ab 57,00 €

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N6-Methyladenosine 5'-monophosphate (sodium salt)

Artikelnummer: Cay23382-5

N6-Methyladenosine 5'-monophosphate is an activator of glycogen phosphorylase b (Ka = 22 µM). It is also a non-competitive inhibitor of rat adenylate kinase II (Ki = 4.2 mM). N6-Methyladenosine 5'-monophosphate (sodium salt) has been used for immunoprecipitation of N6-methyladenosine.Formal Name:...

Schlagworte:	N6-Methyl-AMP, N-methyl-5'-adenylic acid, disodium salt
Anwendung:	Glycogen phosphorylase b activator
CAS	81921-35-9
MW:	405.2 D

ab 163,00 €

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CP-91149

Artikelnummer: TGM-T6455-5mg

Description: CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 µM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose. Target: Phosphorylase. Smiles: CN(C)C(=O)[C@H](O)[C@H](Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1. References: Martin WH, et al. Proc Natl Acad...

Anwendung:	Glycogen phosphorylase inhibitor
CAS	186392-40-5
MW:	399.87 D

ab 45,00 €

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Glycogen Phosphorylase Inhibitor

Artikelnummer: Cay17578-1

Glycogen phosphorylase in the liver, muscle, and brain initiate glycogenolysis by releasing glucose-1-phosphate from glycogen. Glycogen phosphorylase inhibitor is a cell-permeable acyl urea first identified as an inhibitor of human liver glycogen phosphorylase (IC50 = 53 nM). It blocks glucagon-induced hepatic...

Schlagworte:	GPI, 2-chloro-4,5-difluoro-N-[[[2-methoxy-5-[[(methylamino)carbonyl]amino]phenyl]amino]carbonyl]-benzamide
Anwendung:	Cell-permeable human liver glycogen phosphorylase inhibitor
CAS	648926-15-2
MW:	412.8 D

ab 145,00 €

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4-Methylumbelliferyl-beta-D-Glucopyranoside

Artikelnummer: Cay20948-250

4-Methylumbelliferyl-beta-D-Glucopyranoside (4-MUG) is a fluorogenic substrate of beta-glucosidase and beta-glucocerebrosidase (also known as glucosylceramidase). In addition to its use in characterizing novel beta-glucosidases, 4-MUG is used in assays to evaluate deficiency in beta- glucocerebrosidase activity...

Schlagworte:	4-MUG, 4-MU-GLU, 4-MU-beta-Gluc, MU-GLU, 7-(beta-D-glucopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
Anwendung:	Fluorogenic beta-glucosidase & glucosylceramidase substrate
CAS	18997-57-4
MW:	338.3 D

ab 49,00 €

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Anti-PYGL

Artikelnummer: A304-361A

Protein function: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. [The UniProt Consortium]

Schlagworte:	Anti-PYGL, EC=2.4.1.1, Anti-Glycogen phosphorylase, liver form
Anwendung:	WB, IP
Wirt:	Rabbit
Spezies-Reaktivität:	human, mouse

ab 165,00 €

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CP 91,149

Artikelnummer: Cay17709-5

CP 91,149 is an inhibitor of human liver glycogen phosphorylase a (LGPa), muscle glycogen phosphorylase a (MGPa), and MGPb (IC50s = 0.13, 0.2, and 0.3 µM, respectively, in the presence of glucose). CP 91,149 is 5- to 10-fold less potent in the absence of glucose. In vitro, it inhibits glucagon-stimulated...

Schlagworte:	5-chloro-N-[(1S,2R)-3-(dimethylamino)-2-hydroxy-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide
Anwendung:	Glycogen phosphorylase inhibitor
CAS	186392-40-5
MW:	399.9 D