Zu "K00683" wurden 71 Artikel gefunden!
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SEN-177
Artikelnummer: Cay40449-25
SEN-177 is a glutaminyl cyclase inhibitor (IC50 = 53 nM). It reduces polyglutamine aggregation in HeLa cells expressing EGFP-HTT-Q74, an in vitro model of Huntington's disease when used at concentrations of 12.5 and 25 µM. SEN-177 (50 µM) reduces polyglutamine aggregation in primary mouse neurons expressing...
| Schlagworte: | 6'-fluoro-2-[4-(4-methyl-4H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3'-bipyridine |
| Anwendung: | Glutaminyl cyclase inhibitor |
| CAS | 2117405-13-5 |
| MW: | 338.4 D |
ab 73,00 €
Human QPCTL ELISA Kit
Artikelnummer: G-HUFI01753.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Human Glutaminyl-peptide cyclotransferase ELISA Kit
Artikelnummer: G-HUFI01760.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-QPCTL
Artikelnummer: G-PACO40906.50
QPCTL Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IF applications. QPCTL Antibody is a high quality polyclonal antibody for research use only.. Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. [The UniProt Consortium]
| Schlagworte: | Anti-gQC, Anti-QPCTL, Anti-isoQC, EC=2.3.2.5, Anti-Glutaminyl-peptide cyclotransferase-like protein, Anti-Golgi-resident... |
| Anwendung: | ELISA, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
313,00 €
Anti-QPCT
Artikelnummer: ATA-HPA008406.100
Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
| Schlagworte: | Anti-QC, Anti-EC, Anti-sQC, Anti-QPCT, EC=2.3.2.5, Anti-Glutamyl cyclase, Anti-Glutaminyl cyclase, Anti-Glutaminyl-tRNA... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-QPCTL
Artikelnummer: ATA-HPA040797.100
Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 89% and to rat: 90%
| Schlagworte: | Anti-gQC, Anti-isoQC, Anti-QPCTL, EC=2.3.2.5, Anti-Glutaminyl-peptide cyclotransferase-like protein, Anti-Golgi-resident... |
| Anwendung: | IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
L-Pyroglutamic Acid
Artikelnummer: Cay36531-1
L-Pyroglutamic acid is a cyclized form of L-glutamic acid (Cay-30377). It is formed from L-glutamic acid or L-glutamine (Cay-23716) by glutaminyl cyclase. A pyroglutamic acid-containing amyloid-beta (Abeta) peptide (pGlu-Abeta (3-42)) aggregates at a higher rate than Abeta (3-42) and Abeta42 (Cay-20574) when used at...
| Schlagworte: | (-)-Pyroglutamic Acid, (S)-5-Oxoproline, 5-oxo-L-Proline, NSC 143034, 5-oxo-L-proline |
| Anwendung: | L-glutamic acid cyclized form |
| CAS | 98-79-3 |
| MW: | 129.1 D |
ab 84,00 €
Human QPCT (Glutaminyl Peptide Cyclotransferase) ELISA Kit
Artikelnummer: ELK-ELK3384.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human QPCT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human QPCT. Next,...
| Schlagworte: | QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Glutaminyl-peptide cyclotransferase (QPCT), human,...
Artikelnummer: CSB-BP019135HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 29-361aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR...
| Schlagworte: | QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 41.8 kD |
ab 332,00 €
Glutaminyl-peptide cyclotransferase (QPCT), human,...
Artikelnummer: CSB-EP019135HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 29-361aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR SFSNIISTLN PTAKRHLVLA...
| Schlagworte: | QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 53.9 kD |
ab 219,00 €
Glutaminyl-peptide cyclotransferase (Qpct), mouse,...
Artikelnummer: CSB-EP019135MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 36-362aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: AWTQEKNHHQ PAHLNSSSLQ QVAEGTSISE MWQNDLRPLL IERYPGSPGS YSARQHIMQR IQRLQAEWVV EVDTFLSRTP YGYRSFSNII STLNPEAKRH LVLACHYDSK YFPRWDSRVF...
| Schlagworte: | QC, Qpct, EC=2.3.2.5, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide cyclotransferase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 41.6 kD |
ab 292,00 €
Glutaminyl-peptide cyclotransferase (QPCT), human,...
Artikelnummer: CSB-YP019135HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 29-361aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR SFSNIISTLN PTAKRHLVLA CHYDSKYFSH...
| Schlagworte: | QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 40.4 kD |
ab 265,00 €