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SEN-177
SEN-177

Artikelnummer: Cay40449-10

SEN-177 is a glutaminyl cyclase inhibitor (IC50 = 53 nM). It reduces polyglutamine aggregation in HeLa cells expressing EGFP-HTT-Q74, an in vitro model of Huntington's disease when used at concentrations of 12.5 and 25 µM. SEN-177 (50 µM) reduces polyglutamine aggregation in primary mouse neurons expressing...
Schlagworte: 6'-fluoro-2-[4-(4-methyl-4H-1,2,4-triazol-3-yl)-1-piperidinyl]-3,3'-bipyridine
Anwendung: Glutaminyl cyclase inhibitor
CAS 2117405-13-5
MW: 338.4 D
ab 66,00 €
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Human QPCT (Glutaminyl Peptide Cyclotransferase) ELISA Kit
Human QPCT (Glutaminyl Peptide Cyclotransferase) ELISA Kit

Artikelnummer: ELK-ELK3384.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human QPCT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human QPCT. Next,...
Schlagworte: QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide...
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Human QPCTL ELISA Kit
Human QPCTL ELISA Kit

Artikelnummer: G-HUFI01753.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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Human Glutaminyl-peptide cyclotransferase ELISA Kit
Human Glutaminyl-peptide cyclotransferase ELISA Kit

Artikelnummer: G-HUFI01760.96

Anwendung: ELISA
Spezies-Reaktivität: human
641,00 €
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Human QPCT ELISA Kit
Human QPCT ELISA Kit

Artikelnummer: ARG82748.96

Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
Schlagworte: QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide...
Anwendung: ELISA
Spezies-Reaktivität: human
1.416,00 €
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Anti-QPCT
Anti-QPCT

Artikelnummer: G-CAB6711.100

Anwendung: IF, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 352,00 €
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Anti-QPCTL
Anti-QPCTL

Artikelnummer: G-PACO40906.50

QPCTL Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Human and for use in ELISA, IF applications. QPCTL Antibody is a high quality polyclonal antibody for research use only.. Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. [The UniProt Consortium]
Schlagworte: Anti-gQC, Anti-QPCTL, Anti-isoQC, EC=2.3.2.5, Anti-Glutaminyl-peptide cyclotransferase-like protein, Anti-Golgi-resident...
Anwendung: ELISA, IF
Wirt: Rabbit
Spezies-Reaktivität: human
363,00 €
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Anti-QPCT
Anti-QPCT

Artikelnummer: ATA-HPA008406.100

Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
Schlagworte: Anti-QC, Anti-EC, Anti-sQC, Anti-QPCT, EC=2.3.2.5, Anti-Glutamyl cyclase, Anti-Glutaminyl cyclase, Anti-Glutaminyl-tRNA...
Anwendung: IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 335,00 €
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Anti-QPCTL
Anti-QPCTL

Artikelnummer: ATA-HPA040797.100

Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 89% and to rat: 90%
Schlagworte: Anti-gQC, Anti-isoQC, Anti-QPCTL, EC=2.3.2.5, Anti-Glutaminyl-peptide cyclotransferase-like protein, Anti-Golgi-resident...
Anwendung: IHC, ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 335,00 €
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PBD-150
PBD-150

Artikelnummer: Cay36112-10

PBD-150 is an inhibitor of glutaminyl cyclase (Ki = 0.49 µM for the human enzyme). It inhibits the formation of the pyroglutamic acid-containing amyloid-beta (Abeta) peptides pGlu-Abeta (3-40) and pGlu-Abeta (3-42) in HEK293 cells expressing human glutaminyl cyclase and human amyloid precursor protein (APP) with an...
Schlagworte: N-(3,4-dimethoxyphenyl)-N'-[3-(1H-imidazol-1-yl)propyl]-thiourea
Anwendung: Glutaminyl cyclase inhibitor
CAS 790663-33-1
MW: 320.4 D
ab 57,00 €
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Recombinant Human Glutaminyl cyclase / QPCT Protein (His tag)
Recombinant Human Glutaminyl cyclase / QPCT Protein (His...

Artikelnummer: E-PKSH030564.50

Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
Ursprungsart: human
1.025,00 €
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Anti-QPCT
Anti-QPCT

Artikelnummer: ELK-ES13831.100

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008], Protein function: Responsible for the...
Schlagworte: Anti-QC, Anti-EC, Anti-sQC, Anti-QPCT, EC=2.3.2.5, Anti-Glutamyl cyclase, Anti-Glutaminyl cyclase, Anti-Glutaminyl-tRNA...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 169,00 €
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