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Zu "K00683" wurden 61 Artikel gefunden!
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Artikelnummer: ABS-KC-2314.100
Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
Schlagworte: | Anti-Glutaminyl-peptide cyclotransferase, Anti-Glutaminyl cyclase, Anti-QC, Anti-sQC, Anti-Glutaminyl-tRNA... |
Anwendung: | IHC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 206,00 €
Artikelnummer: ABS-KC-2315.100
Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
Schlagworte: | Anti-Glutaminyl-peptide cyclotransferase, Anti-Glutaminyl cyclase, Anti-QC, Anti-sQC, Anti-Glutaminyl-tRNA... |
Anwendung: | IHC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 206,00 €
Artikelnummer: ABS-KC-2316.100
Protein function: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N- terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes...
Schlagworte: | Anti-Glutaminyl-peptide cyclotransferase, Anti-Glutaminyl cyclase, Anti-QC, Anti-sQC, Anti-Glutaminyl-tRNA... |
Anwendung: | IHC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 206,00 €
Artikelnummer: TGM-T7905-100mg
Description: PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM). Target: Beta Amyloid. Smiles: COc1ccc(NC(=S)NCCCn2ccnc2)cc1OC. References: Huang, K.-F, Liaw, S.-S, Huang, W.-L,et al. Structures of Human Golgi-resident Glutaminyl Cyclase and Its Complexes with Inhibitors...
Anwendung: | Glutaminyl cyclase inhibitor |
CAS | 790663-33-1 |
MW: | 320.41 D |
ab 31,00 €
Artikelnummer: TGM-TMPH-01395-100ug
Description: Responsible for the biosynthesis of pyroglutamyl peptides. QPCTL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.5 kDa and the accession number is Q9NXS2.
Schlagworte: | Golgi-resident glutaminyl-peptide cyclotransferase, Glutaminyl-peptide cyclotransferase-like protein, isoQC, QPCTL |
MW: | 35.5 kD |
ab 198,00 €
Artikelnummer: TGM-TMPH-02679-100ug
Description: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The...
Schlagworte: | Glutaminyl-tRNA cyclotransferase, Glutaminyl cyclase, Qpct, Glutaminyl-peptide cyclotransferase |
MW: | 39.6 kD |
ab 281,00 €
Artikelnummer: TGM-TMPH-02680-100ug
Description: Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. QPCT Protein, Mouse, Recombinant (His & Myc) is expressed in HEK293 mammalian...
Schlagworte: | Glutaminyl-peptide cyclotransferase, Glutaminyl-tRNA cyclotransferase, Glutaminyl cyclase, Qpct |
MW: | 41.6 kD |
ab 464,00 €
Artikelnummer: TGM-TMPY-03260-50ug
Description: Glutaminyl cyclase, also known as QPCT, can promote the N-terminal cyclization reaction of N-terminal pyroglutamate(pGlu). The pGlu formation from its glutaminyl precursor is required in the maturation of numerous bioactive peptides, while the aberrant formation of pGlu may be related to several...
Schlagworte: | glutaminyl-peptide cyclotransferase, sQC, QC, GCT |
MW: | 39.7 kD |
599,00 €
Artikelnummer: TGM-T11422-100mg
Description: Glutaminyl Cyclase Inhibitor 3, a designed anti-Alzheimer's compound, is a potent human Glutaminyl Cyclase (GC) inhibitor (IC50: 4.5 nM). It significantly reduced the brain concentrations of pyroform Abeta and total Abeta and restored cognitive functions. Target: Others. Smiles:...
Anwendung: | Glutaminyl Cyclase inhibitor |
CAS | 2092921-50-9 |
MW: | 468.61 D |
ab 2.151,00 €
Artikelnummer: TGM-T11424-100mg
Description: Glutaminyl Cyclase Inhibitor 1, a glutaminyl cyclase inhibitor with an IC50 of 0.5 µM, can be utilized for studying neurological disorders. Target: Guanylate cyclase. Smiles: COc1ccc(cc1OC)-c1cccc(F)c1NCCCn1cnc(C)c1. References: Li M, et al. Synthesis and Evaluation of Diphenyl Conjugated Imidazole...
Anwendung: | Glutaminyl Cyclase inhibitor |
CAS | 2110449-60-8 |
MW: | 369.43 D |
ab 120,00 €
Artikelnummer: TGM-T11425-100mg
Description: Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor with an IC50 of 1.23 µM. Target: Others. Smiles: N(CCCN1C=C(C)N=C1)C2=C(C=CC=C2)C3=CC=C(F)C=C3. References: Li M, et al. Synthesis and Evaluation of Diphenyl Conjugated Imidazole Derivatives as Potential Glutaminyl Cyclase Inhibitors for...
Anwendung: | Glutaminyl Cyclase inhibitor |
CAS | 1884546-29-5 |
MW: | 309.38 D |
ab 1.520,00 €
Artikelnummer: CSB-BP019135HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 29-361aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR...
Schlagworte: | QC, EC, sQC, QPCT, EC=2.3.2.5, Glutamyl cyclase, Glutaminyl cyclase, Glutaminyl-tRNA cyclotransferase, Glutaminyl-peptide... |
Anwendung: | Activity not tested |
Exprimiert in: | Insect cells |
Ursprungsart: | human |
MW: | 41.8 kD |
ab 332,00 €