Zu "K00567" wurden 104 Artikel gefunden!
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Lomeguatrib
Artikelnummer: Cay11732-10
O6-Methylguanine-DNA methyltransferase (MGMT) (Cay-11176) is a DNA repair protein which removes an alkyl group from the O6 position on guanine in an autoinactivating reaction. Although important in normal DNA repair, this reaction confers resistance to treatments that use O6-alkylating agents to produce...
| Schlagworte: | PaTrin 2, 6-[(4-bromo-2-thienyl)methoxy]-9H-purin-2-amine |
| Anwendung: | MGMT inhibitor |
| CAS | 192441-08-0 |
| MW: | 326.2 D |
ab 57,00 €
O6-Benzylguanine
Artikelnummer: Cay16332-10
O6-Alkylguanine-DNA alkyltransferase (AGT, also known as methylguanine DNA methyltransferase, or MGMT) is a DNA repair protein that directly removes alkyl groups located on the O6-position of guanine from DNA, restoring DNA integrity in a single step. In the process, AGT is alkylated and irreversibly inactivated....
| Schlagworte: | NSC 637037, 6-(phenylmethoxy)-9H-purin-2-amine |
| Anwendung: | MGMT inhibitor |
| CAS | 19916-73-5 |
| MW: | 241.2 D |
ab 49,00 €
O6-Benzylguanine
Artikelnummer: LKT-B1855.50
| Anwendung: | MGMT inhibitor |
| CAS | 19916-73-5 |
| MW: | 241,25 D |
ab 118,00 €
O6-Benzylguanine
Artikelnummer: TGM-T7539-25mg
Description: O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator. Target: DNA/RNA Synthesis, Apoptosis, DNA Alkylation. Smiles: O(CC1=CC=CC=C1)C2=C3C(=NC(N)=N2)N=CN3. References: Tacastacas J D , Chan D V , Carlson S . Evaluation...
| Anwendung: | MGMT inhibitor |
| CAS | 19916-73-5 |
| MW: | 241.25 D |
ab 40,00 €
O6-methylguanine-DNA Methyltransferase (human, recombinant)
Artikelnummer: Cay11176-100
O6-methylguanine-DNA Methyltransferase (MGMT) is a DNA repair enzyme responsible for demethylating O6-methylguanine (O6-mG). The methylation of guanine at O6 to form O6-mG allows base-pairing to thymine rather than cytosine during DNA replication. MGMT prevents mutations by transferring the methyl group from O6-mG...
| Schlagworte: | O-6-methylguanine-DNA-alkyltransferase, O-6-methylguanine-DNA-alkyltransferase, 6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | Demethylation studies |
| MW: | 26,8 kD |
570,00 €
Human MGMT ELISA Kit
Artikelnummer: G-HUFI01727.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-MGMT
Artikelnummer: NSJ-R31679
0.5mg/ml if reconstituted with 0.2ml sterile DI water.
| Schlagworte: | Anti-MGMT, EC=2.1.1.63, Anti-O-6-methylguanine-DNA-alkyltransferase, Anti-6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | WB, IHC (paraffin), ICC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-MGMT, NT (MGMT, Methylated-DNA-protein-cysteine...
Artikelnummer: 038417.200
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated....
| Schlagworte: | Anti-MGMT, EC=2.1.1.63, Anti-O-6-methylguanine-DNA-alkyltransferase, Anti-6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | ELISA, FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
Anti-MGMT, NT (MGMT, Methylated-DNA-protein-cysteine...
Artikelnummer: 038418.200
MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated....
| Schlagworte: | Anti-MGMT, EC=2.1.1.63, Anti-O-6-methylguanine-DNA-alkyltransferase, Anti-6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | ELISA, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
865,00 €
Anti-MGMT, clone SQab1861
Artikelnummer: ARG66313.100
Protein function: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme...
| Schlagworte: | Anti-MGMT, EC=2.1.1.63, Anti-O-6-methylguanine-DNA-alkyltransferase, Anti-6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | FC, IHC (paraffin), IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 460,00 €
Anti-MGMT
Artikelnummer: NSJ-F50325-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. This protein repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a...
| Schlagworte: | Anti-MGMT, EC=2.1.1.63, Anti-O-6-methylguanine-DNA-alkyltransferase, Anti-6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | IHC, FC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-MGMT, clone 888CT22.2.4
Artikelnummer: NSJ-F52339-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the...
| Schlagworte: | Anti-MGMT, EC=2.1.1.63, Anti-O-6-methylguanine-DNA-alkyltransferase, Anti-6-O-methylguanine-DNA methyltransferase,... |
| Anwendung: | IHC, IF, WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 361,00 €