Zu "K00546" wurden 49 Artikel gefunden!
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Anti-HNMT Monoclonal Recombinant Antibody
Artikelnummer: E-AN300161P.100
In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the...
| Schlagworte: | HMT, HNMT, Histamine N-methyltransferase, Recombinant HNMT Monoclonal Antibody |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
462,00 €
1-Methylhistamine (hydrochloride)
Artikelnummer: Cay19516-10
1-Methylhistamine is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer's disease patients as well as those with hypersomnia and other neurological conditions.Formal Name:...
| Schlagworte: | tele-Methylhistamine, N1-Methylhistamine, Ntau-Methylhistamine, 1-methyl-H-imidazole-4-ethanamine, dihydrochloride |
| Anwendung: | Histidine metabolism metabolite |
| CAS | 6481-48-7 |
| MW: | 198.1 D |
ab 181,00 €
Metoprine
Artikelnummer: Cay43098-10
Metoprine is an inhibitor of histamine N-methyltransferase (HNMT, IC50 = 91 nM). It is also an inhibitor of dihydrofolate reductase (Dhfr, IC50s = 1, 1. and 60 µM for the chicken, rat, and T. equiperdum enzymes, respectively). Metoprine (10 mg/kg) increases the levels of histamine in mouse cerebral cortex,...
| Schlagworte: | DDMP, NSC 19494, NSC 7364, 5-(3,4-dichlorophenyl)-6-methyl-2,4-pyrimidinediamine |
| Anwendung: | HNMT inhibitor, antineoplastic |
| CAS | 7761-45-7 |
| MW: | 269.13 D |
ab 147,00 €
Amodiaquine
Artikelnummer: Cay15954-1
Amodiaquine is a prodrug form of the antimalarial compound N-desethyl amodiaquine (Cay-20822). It is active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and exhibits a synergistic effect when used in combination with N-desethyl amodiaquine. Amodiaquine dose-dependently inhibits...
| Schlagworte: | Camoquine, Flavoquine, NSC 13453, SN 10751, 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-phenol |
| Anwendung: | Antimalarial, HNMT inhibitor |
| CAS | 86-42-0 |
| MW: | 355.9 D |
ab 56,00 €
Anti-HNMT, clone 432CT31.4.2
Artikelnummer: ARG56213.100
Protein function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [The UniProt Consortium]
| Schlagworte: | Anti-HMT, Anti-HNMT, Anti-Histamine N-methyltransferase |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
616,00 €
Anti-HNMT
Artikelnummer: ARG56272.100
Protein function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [The UniProt Consortium]
| Schlagworte: | Anti-HMT, Anti-HNMT, Anti-Histamine N-methyltransferase |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Human HNMT(Histamine N-methyltransferase) ELISA Kit
Artikelnummer: G-HUFI03084.96
Protein function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [The UniProt Consortium]
| Schlagworte: | HMT, HNMT, Histamine N-methyltransferase |
698,00 €
Amodiaquine-d10
Artikelnummer: Cay28525-1
Amodiaquine-d10 is intended for use as an internal standard for the quantification of amodiaquine (Cay-15954) by GC- or LC-MS. Amodiaquine is a prodrug form of the antimalarial compound N-desethyl amodiaquine (Cay-20822). It is active against several strains of P. falciparum in vitro (EC50s = 0.23-0.52 nM) and...
| Schlagworte: | Camoquine-d10, Flavoquine-d10, 2-((bis(ethyl-d5)amino)methyl)-4-((7-chloroquinolin-4-yl)amino)phenol |
| Anwendung: | GC-MS, LC-MS, internal standard, quantification, antimalarial, HNMT inhibitor |
| CAS | 1189449-70-4 |
| MW: | 365.9 D |
409,00 €
Anti-HNMT
Artikelnummer: ATA-HPA035481.100
Protein function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 88% and...
| Schlagworte: | Anti-HMT, Anti-HNMT, Anti-Histamine N-methyltransferase |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
Anti-HNMT
Artikelnummer: ATA-HPA035480.100
Protein function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and...
| Schlagworte: | Anti-HMT, Anti-HNMT, Anti-Histamine N-methyltransferase |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Histamine N-methyltransferase (Hnmt), mouse, recombinant
Artikelnummer: CSB-EP010598MO.1
Organism: Mus musculus (Mouse). Source: E.coli. Expression Region: 1-295aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MASCMRSLFS DQGRYVESFR RFLNNSTEHQ CMQEFMDKKL PGIIARIGEA KAEIKILSVG GGAGEVDLQI LSKVQAQYPG ICINNEVVEP SAEQIVKYKE LVAKTSNMEN...
| Schlagworte: | HMT, Hmt, Hnmt, Histamine N-methyltransferase, Recombinant Mouse Histamine N-methyltransferase (Hnmt) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | mouse |
| MW: | 41.1 kD |
ab 292,00 €
1-Methylhistamine dihydrochloride
Artikelnummer: TGM-T8790-100mg
Description: 1-Methylhistamine dihydrochloride is a major metabolite of histamine by histamine N-methyltransferase in the pathway of histidine metabolism. It has been used as a biomarker of histaminergic system activity in the brains of Alzheimer's disease patients as well as those with hypersomnia and other...
| Anwendung: | Histidine metabolism metabolite |
| CAS | 6481-48-7 |
| MW: | 198.09 D |
ab 32,00 €