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Zu "K00545" wurden 67 Artikel gefunden!
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Artikelnummer: NSJ-RQ5527
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Catechol O-methyltransferase, also called COMT, is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines. This gene is mapped to 22q11.21. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from...
Schlagworte: | Anti-Catechol O-methyltransferase, COMT Antibody |
Anwendung: | WB, IHC (paraffin), IF, FC |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: NSJ-RQ5590
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Leucine rich transmembrane and O-methyltransferase domain containing is a protein that in humans is encoded by the LRTOMT gene. It is mapped to 11q13.4. This gene has evolved in primates as a fusion of two ancestral neighboring genes, Lrrc51 and Tomt, which...
Schlagworte: | Anti-PP7517, Anti-Protein LRTOMT2, Anti-Catechol O-methyltransferase 2, Anti-Transmembrane O-methyltransferase, LRTOMT... |
Anwendung: | WB, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Artikelnummer: Cay38792-100
Normetanephrine is an active metabolite of norepinephrine. It is formed from norepinephrine by catechol-O-methyltransferase (COMT). Normetanephrine induces contractions in isolated rabbit aortic strips in a concentration-dependent manner. It inhibits norepinephrine uptake in isolated rat heart (IC50 = 200 µM)....
Schlagworte: | (±)-Normetadrenaline, DL-Normetanephrine, NMN, alpha-(aminomethyl)Vanillyl Alcohol,... |
Anwendung: | Active norepinephrine metabolite |
CAS | 1011-74-1 |
MW: | 219.7 D |
ab 52,00 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK3245.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human COMT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human COMT. Next,...
Schlagworte: | Catechol O-methyltransferase |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK6489.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse COMT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse COMT. Next,...
Schlagworte: | Comt1, Catechol O-methyltransferase |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
365,00 €
ab 328,50 €
-10 %
Rabattaktion
Artikelnummer: ELK-ELK6527.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat COMT. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat COMT. Next,...
Schlagworte: | Catechol O-methyltransferase |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
365,00 €
ab 328,50 €
Artikelnummer: Cay29674-1
Tropolone is a terpene that has been found in cupressaceous tree bark and has diverse biological activities. It inhibits catechol O-methyltransferase (COMT, Ki = 22 µM). Tropolone is bacteriostatic against a panel of Gram-positive and Gram-negative bacteria (MICs = 12-82 µM) and bactericidal against A. hydrophilia...
Schlagworte: | 2-Hydroxytropone, NSC 89303, Purpurocatechol, alpha-Tropolone, 2-hydroxy-2,4,6-cycloheptatrien-1-one |
Anwendung: | Bioactive terpene |
CAS | 533-75-5 |
MW: | 122.1 D |
ab 32,00 €
Artikelnummer: Cay14153-10
Entacapone is a reversible catechol O-methyltransferase (COMT) inhibitor (IC50s = 10, 10, 20, and 160 nM for rat duodenum, brain, erythrocyte, and liver COMT, respectively). It is selective for COMT over monoamine oxidase A (MAO-A) and MAO-B and phenolsulphotransferase M (PST-M) and PST-P (IC50s = >50 µM)....
Schlagworte: | OR-611, 2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2E-propenamide |
Anwendung: | COMT inhibitor |
CAS | 130929-57-6 |
MW: | 305.3 D |
ab 60,00 €
Artikelnummer: Cay20768-5
Tolcapone is a reversible inhibitor of catechol-O-methyltransferase (COMT, Ki = 0.27 nM for human recombinant COMT), an enzyme that degrades catecholamines, including dopamine and L-DOPA (Cay-13248). Tolcapone crosses the blood brain barrier and can inhibit both peripheral and central COMT activity. By inhibiting...
Schlagworte: | Ro 40-7592, (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)-methanone |
Anwendung: | Reversible COMT inhibitor |
CAS | 134308-13-7 |
MW: | 273.2 D |
ab 52,00 €
Artikelnummer: Cay34155-50
2-methoxy Estrone is an active metabolite of the endogenous estrogen estrone (Cay-10006485). It is formed from estrone by catechol-O-methyltransferase (COMT). 2-methoxy Estrone inhibits the proliferation of isolated bovine brain-derived capillary endothelial cells (IC50 = 11.5 µM). It increases the levels of 6-keto...
Schlagworte: | 2-MeOE1, 2-methoxy E1, 3-hydroxy-2-methoxy-estra-1,3,5(10)-trien-17-one |
Anwendung: | Estrone active metabolite |
CAS | 362-08-3 |
MW: | 300.4 D |
ab 82,00 €
Artikelnummer: Cay15408-10
Metanephrine is an inactive metabolite of epinephrine (Cay-21245). It is formed from epinephrine by catechol-O-methyl transferase (COMT). Urinary and plasma levels of metanephrine are increased in patients with pheochromocytoma, an adrenal medullary neuroendocrine tumor.Formal Name:...
Schlagworte: | 4-hydroxy-3-methoxy-alpha-[(methylamino)methyl]-benzenemethanol |
Anwendung: | Epinephrine COMT metabolite |
CAS | 5001-33-2 |
MW: | 197.2 D |
ab 84,00 €
Artikelnummer: Cay29689-50
Purpurogallin is a phenol that has been found in D. divisa and a derivative of pyrogallol (Cay-20347) that has diverse biological activities, including antimicrobial, antioxidant, and enzyme inhibitory properties. It is active against the Gram-positive bacteria S. aureus, methicillin-resistant S. aureus (MRSA), S....
Schlagworte: | NCI 35676, NSC 35676, NSC 646653, 2,3,4,6-tetrahydroxy-5H-benzocyclohepten-5-one |
Anwendung: | Bioactive pyrogallol derivative |
CAS | 569-77-7 |
MW: | 220.2 D |
ab 52,00 €