Zu "K00545" wurden 97 Artikel gefunden!
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Anti-COMT
Artikelnummer: ABS-KC-2556.100
Protein function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. [The UniProt Consortium]
| Schlagworte: | Anti-Catechol O-methyltransferase, COMT Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Anti-COMT
Artikelnummer: ABS-KC-2779.100
Protein function: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. [The UniProt Consortium]
| Schlagworte: | Anti-Catechol O-methyltransferase, COMT Antibody |
| Anwendung: | IP |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Tolcapone
Artikelnummer: TGM-T6708-100mg
Description: Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor employed as an adjunctive therapy with levodopa and carbidopa in the treatment of Parkinson's disease. Target: Apoptosis, Transferase, Beta Amyloid. Smiles: C(=O)(C1=CC(N(=O)=O)=C(O)C(O)=C1)C2=CC=C(C)C=C2. References: Zürcher G, et al....
| Schlagworte: | Ro 40-7592, Tasmar |
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 134308-13-7 |
| MW: | 273.24 D |
ab 33,00 €
2-Methoxyestrone
Artikelnummer: TGM-T13481-10mg
Description: 2-Methoxyestrone is a methoxylated catechol estrogen and the principal metabolite of 2-hydroxyestrone [a nonuterotropic metabolite of estradiol]. Target: Endogenous Metabolite. Smiles: [H][C@@]12CCC(=O)[C@@]1(C)CC[C@]1([H])c3cc(OC)c(O)cc3CC[C@@]21[H]. References: Lewis KM, et al. pKa values of estrone,...
| Anwendung: | Estrone active metabolite |
| CAS | 362-08-3 |
| MW: | 300.39 D |
ab 57,00 €
Opicapone
Artikelnummer: TGM-T16398-100mg
Description: Opicapone (BIA 9-1067) reduces the ATP content of the cells (IC50: 98 µM). Opicapone is an effective third-generation catechol-O-methyltransferase inhibitor for the research of Parkinson's disease and motor fluctuations. Target: Transferase. Smiles:...
| Schlagworte: | BIA 9-1067 |
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 923287-50-7 |
| MW: | 413.17 D |
ab 60,00 €
Purpurogallin
Artikelnummer: TGM-T16685-100mg
Description: Purpurogallin, a naturally occurring phenol extracted from Quercus spp. plants, exhibits potent xanthine oxidase inhibitory activity (IC50: 0.2 µM) and also possesses antioxidant and anti-inflammatory effects. Target: Xanthine Oxidase. Smiles: Oc1cc2cccc(O)c(=O)c2c(O)c1O. References: Park HY, et al....
| Anwendung: | Bioactive pyrogallol derivative |
| CAS | 569-77-7 |
| MW: | 220.18 D |
ab 48,00 €
3-O-methyl-L-DOPA (hydrate)
Artikelnummer: TGM-T36122-10mg
Description: 3-O-methyl-L-DOPA is a metabolite of L-DOPA , produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA. Target: Others. Smiles: O.COc1cc(C[C@H](N)C(O)=O)ccc1O
| Anwendung: | COMT L-DOPA metabolite |
| CAS | 200630-46-2 |
| MW: | 229.23 D |
ab 62,00 €
Methylspinazarin
Artikelnummer: TGM-T36207-5mg
Description: Methylspinazarin is a naphthoquinone bacterial metabolite that has been found in Streptomyces and is an inhibitor of catechol O-methyltransferase (COMT, IC50 = 0.8 µg/ml).1 It is selective for COMT over tyrosine hydroxylase, DOPA decarboxylase, and dopamine-beta-hydroxylase at 100 µg/ml....
| Anwendung: | Naphthoquinone bacterial metabolite, COMT inhibitor |
| CAS | 41768-12-1 |
| MW: | 236.179 D |
2.169,00 €
3-Methoxytyramine hydrochloride
Artikelnummer: TGM-T4710-100mg
Description: 3-Methoxytyramine hydrochloride (3-O-methyl Dopamine hydrochloride) is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be found primarily in human brain and most tissues tissues, and in blood, cerebrospinal fluid (csf) or urine....
| Schlagworte: | 3-O-methyl Dopamine hydrochloride, 3-O-methyl Dopamine hydrochloride) |
| Anwendung: | Dopamine metabolite |
| CAS | 1477-68-5 |
| MW: | 203.666 D |
ab 30,00 €
Normetanephrine hydrochloride
Artikelnummer: TGM-T4945-100mg
Description: Normetanephrine hydrochloride (DL-Normetanephrine hydrochloride) is a metabolite of Epinephrine. It is found together with Metanephrine in urine and in certain tissues. Target: Endogenous Metabolite. Smiles: Cl.COc1cc(ccc1O)C(O)CN. References: Eisenhofer, G., et al.: J. Clin. Endocrinol. Metab., 82,...
| Schlagworte: | DL-Normetanephrine hydrochloride |
| Anwendung: | Active norepinephrine metabolite |
| CAS | 1011-74-1 |
| MW: | 219.665 D |
ab 57,00 €
Nitecapone
Artikelnummer: TGM-T7831-100mg
Description: Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver). Target: Transferase, Others. Smiles: CC(=O)C(=Cc1cc(O)c(O)c(c1)[N+]([O-])=O)C(C)=O. References: P.T. Männistö, Kaakkola S . Catechol-O-methyltransferase (COMT): Biochemistry, molecular biology, pharmacology, and...
| Anwendung: | Targets catechol O-methyltransferase [EC:2.1.1.6] (COMT) |
| CAS | 116313-94-1 |
| MW: | 265.22 D |
ab 42,00 €
Tropolone
Artikelnummer: TGM-T8087-100mg
Description: Tropolone, a metal chelator, possesses weak antioxidative and radical-scavenging properties and shows a strong affinity for ferric ion. Target: Tyrosinase. Smiles: O=C1C(O)=CC=CC=C1. References: Kahn V , Andrawis A . Inhibition of mushroom tyrosinase by tropolone[J]. Phytochemistry, 1985, 24(5):905-908.
| Anwendung: | Bioactive terpene |
| CAS | 533-75-5 |
| MW: | 122.12 D |
30,00 €