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Human SCD (Stearoyl Coenzyme A Desaturase) ELISA Kit
Human SCD (Stearoyl Coenzyme A Desaturase) ELISA Kit

Artikelnummer: ELK-ELK3716.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SCD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SCD. Next,...
Schlagworte: SCD, hSCD1, Delta-9 desaturase, Delta(9)-desaturase, Acyl-CoA desaturase, Fatty acid desaturase, Stearoyl-CoA desaturase
Anwendung: ELISA
Spezies-Reaktivität: human
ab 365,00 €
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Rat SCD (Stearoyl Coenzyme A Desaturase) ELISA Kit
Rat SCD (Stearoyl Coenzyme A Desaturase) ELISA Kit

Artikelnummer: ELK-ELK6966.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat SCD. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat SCD. Next, Avidin...
Schlagworte: Scd, Scd1, Delta-9 desaturase 1, Delta(9)-desaturase 1, Acyl-CoA desaturase 1, Fatty acid desaturase 1, Stearoyl-CoA...
Anwendung: ELISA
Spezies-Reaktivität: rat
ab 365,00 €
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DUN41875
DUN41875

Artikelnummer: Cay37151-100

DUN41875 is an inhibitor of stearyol-CoA desaturase 1 (SCD1, IC50 = 11.8 nM for the rat enzyme). It increases tetramerization of soluble alpha-synuclein and reduces mutant alpha-synuclein incorporation into tetramers in BE(2)-M17 neuroblastoma cells expressing a mutant alpha-synuclein containing three...
Schlagworte: SCD1 Inhibitor, Stearoyl-CoA Desaturase 1 Inhibitor, Stearoyl-Coenzyme A Desaturase 1 Inhibitor,...
Anwendung: Stearoyl-CoA desaturase 1 inhibitor
CAS 1295541-87-5
MW: 363.3 D
ab 119,00 €
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CAY10566
CAY10566

Artikelnummer: Cay10012562-1

Stearoyl-CoA desaturase (SCD) catalyzes the committed step of the conversion of saturated, long-chain fatty acids to monounsaturated fatty acids. The SCD1 gene is thought to play a key role in lipid homeostasis and body weight regulation. Thus, modulating SCD1 activity pharmacologically may be a useful tool for...
Schlagworte: 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)-pyridazine
Anwendung: SCD inhibitor
CAS 944808-88-2
MW: 389.8 D
ab 94,00 €
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GSK1940029
GSK1940029

Artikelnummer: Cay36704-1

GSK1940029 is a stearoyl-CoA desaturase (SCD) inhibitor. It increases palmitate-induced phosphorylation of p70 ribosomal S6 kinase 1 (p70S6K1) and lactate dehydrogenase (LDH) release from AML12 hepatocytes when used at a concentration of 20 µM. GSK1940029 (10 µM) also increases palmitate-induced increases in...
Schlagworte: 1-[(3,4-dichlorophenyl)methyl]-N-[4-(hydroxymethyl)phenyl]-5-methyl-1H-1,2,3-triazole-4-carboxamide
Anwendung: Stearoyl-CoA desaturase inhibitor
CAS 1150701-66-8
MW: 391.3 D
ab 35,00 €
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A-939572
A-939572

Artikelnummer: Cay19123-50

A-939572 inhibits stearoyl-CoA desaturase 1 (IC50 = 6.3 nM), a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs). This compound has been used to induce cell death of hPSCs as well as to inhibit the proliferation of human non-small cell lung carcinoma H1299 cells in...
Schlagworte: SCD1 Inhibitor, Stearoyl-CoA Desaturase 1 Inhibitor,...
Anwendung: Stearoyl-CoA desaturase 1 inhibitor
CAS 1032229-33-6
MW: 387.9 D
ab 70,00 €
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MK-8245
MK-8245

Artikelnummer: Cay29421-10

MK-8245 is a liver-targeted inhibitor of stearoyl-CoA desaturase (SCD, IC50s = 3, 3, and 1 nM for rat, mouse, and human SCD1, respectively). It is selective for SCD1 over Delta5- and Delta6-desaturases (IC50s = >100,000 nM). MK-8245 (20-60 mg/kg) reduces the hepatic, but not Harderian gland, ratio of oleic acid to...
Schlagworte: 5-[3-[4-(2-bromo-5-fluorophenoxy)-1-piperidinyl]-5-isoxazolyl]-2H-tetrazole-2-acetic acid
Anwendung: Stearoyl-CoA desaturase inhibitor
CAS 1030612-90-8
MW: 467.3 D
ab 92,00 €
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SW203668 (trifluoroacetate salt)
SW203668 (trifluoroacetate salt)

Artikelnummer: Cay19379-10

SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM). It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and...
Schlagworte: 4-(aminophenylmethyl)-N-(6-methoxy-2-benzothiazolyl)-benzamide, trifluoroacetate salt
Anwendung: Stearoyl-CoA desaturase inhibitor prodrug
CAS 2117405-48-6
MW: 503.5 D
ab 50,00 €
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PluriSln 1
PluriSln 1

Artikelnummer: Cay16161-5

PluriSln 1 is an N-acyl phenylhydrazine derivative that inhibits stearoyl-CoA desaturase, a key enzyme for lipid metabolism that is expressed in human pluripotent stem cells (hPSCs). PluriSln 1 can selectively induce ER stress, attenuate protein synthesis, and induce apoptosis in hPSCs (EC50 = 2 µM) while sparing...
Schlagworte: N'-phenyl-hydrazine-Isonicotinic acid, NSC 14613, 2-phenylhydrazide-4-pyridinecarboxylic acid
Anwendung: Stearoyl-CoA desaturase inhibitor, HPSC apoptosis inducer
CAS 91396-88-2
MW: 213.2 D
ab 84,00 €
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Sterculic Acid
Sterculic Acid

Artikelnummer: Cay26735-25

Sterculic acid is a cyclopropene fatty acid that has been found in S. foetida. It is an inhibitor of Delta9-desaturase that decreases 9(Z)-myristoleic acid (Cay-9002461) and increases oleic acid (Cay-90260) and 9(Z),11(E)-conjugated linoleic acid (Cay-90140) levels in the milk of lactating ewes when administered at...
Schlagworte: 2-octyl-1-cyclopropene-1-octanoic acid
Anwendung: Cyclopropene fatty acid
CAS 738-87-4
MW: 294.5 D
530,00 €
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MF438
MF438

Artikelnummer: Cay33349-1

MF438 is an inhibitor of stearoyl-CoA desaturase 1 (SCD1, IC50 = 2.3 nM for the rat enzyme), an enzyme that catalyzes the formation of a cis double bond at the ?9 position of stearoyl-CoA to produce oleoyl-CoA. It reduces spheroid formation in NCI H460 and patient-derived non-small cell lung cancer (NSCLC) cells in...
Schlagworte: 3-(5-methyl-1,3,4-thiadiazol-2-yl)-6-[4-[2-(trifluoromethyl)phenoxy]-1-piperidinyl]-pyridazine
Anwendung: Stearoyl-CoA desaturase inhibitor
CAS 921605-87-0
MW: 421.4 D
ab 43,00 €
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Anti-Stearoyl-CoA Desaturase-1 (mouse)
Anti-Stearoyl-CoA Desaturase-1 (mouse)

Artikelnummer: AG-25A-0031-C100

Recognizes mouse SCD1. Detects a band of about 41kDa by Western Blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat...
Schlagworte: SCD1, Acyl-CoA Desaturase 1, Fatty Acid Desaturase 1
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: mouse
286,00 €
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