Zu "K00502" wurden 129 Artikel gefunden!
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Anti-TPH1
Artikelnummer: ABS-KC-2114.100
| Schlagworte: | Anti-Tryptophan 5-hydroxylase 1, Anti-Tryptophan 5-monooxygenase 1, TPH1 Antibody |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 206,00 €
Telotristat Etiprate
Artikelnummer: TGM-T6044-100mg
Description: Telotristat Etiprate (LX 1606 Hippurate) is an orally bioavailable, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Target: Hydroxylase. Smiles: OC(=O)CNC(=O)c1ccccc1.CCOC(=O)[C@@H](N)Cc1ccc(cc1)-c1cc(O[C@H](c2ccc(Cl)cc2-n2ccc(C)n2)C(F)(F)F)nc(N)n1. References: Pappas C,...
| Schlagworte: | LX 1606 Hippurate, LX1606 (Hippurate) |
| Anwendung: | Targets tryptophan 5-monooxygenase [EC:1.14.16.4] (TPH1_2) |
| CAS | 1137608-69-5 |
| MW: | 754.15 D |
ab 40,00 €
6-fluoro-DL-Tryptophan
Artikelnummer: TGM-T7694-100mg
Description: 6-fluoro-DL-Tryptophan is an inhibitor of serotonin (5-HT) synthesis. Target: 5-HT Receptor. Smiles: NC(CC1=CNC2=CC(F)=CC=C12)C(O)=O. References: Chanut E , Zini R , Trouvin J H , et al. Albumin binding and brain uptake of 6-fluoro-DL-tryptophan: competition with L-tryptophan[J]. Biochemical...
| Anwendung: | Serotonin synthesis inhibitor |
| CAS | 7730-20-3 |
| MW: | 222.22 D |
ab 42,00 €
TPH2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-02259-100ug
Description: N/A. TPH2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 60.1 kDa and the accession number is Q8IWU9.
| Schlagworte: | TPH2, Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2, Neuronal tryptophan hydroxylase |
| MW: | 60.1 kD |
ab 236,00 €
Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His...
Artikelnummer: TGM-TMPH-02958-100ug
Description: Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.3 kDa and the accession number...
| Schlagworte: | Tph1, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1 |
| MW: | 67.3 kD |
ab 281,00 €
Tryptophan Hydroxylase 1/TPH-1 Protein, Human,...
Artikelnummer: TGM-TMPY-01959-50ug
Description: Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 contains one ACT domain. Tryptophan hydroxylase catalyzes the biopterin-dependent...
| Schlagworte: | TPRH, tryptophan hydroxylase 1, TRPH |
| MW: | 52.7 kD |
599,00 €
Telotristat ethyl
Artikelnummer: TGM-T11897-100mg
Description: Telotristat ethyl (LX1606) is a orally-delivered inhibitor of tryptophan hydroxylase that reduces serotonin production. Target: Hydroxylase. Smiles: CCOC(=O)[C@@H](N)Cc1ccc(cc1)-c1cc(O[C@H](c2ccc(Cl)cc2-n2ccc(C)n2)C(F)(F)F)nc(N)n1. References: Tamas Oravecz, et al. LX1606 (aka LX1032), a Novel Inhibitor...
| Schlagworte: | LX1606 |
| Anwendung: | Targets tryptophan 5-monooxygenase [EC:1.14.16.4] (TPH1_2) |
| CAS | 1033805-22-9 |
| MW: | 574.98 D |
ab 34,00 €
Rodatristat ethyl
Artikelnummer: TGM-T16779-100mg
Description: Rodatristat ethyl (KAR5585) is a groundbreaking, orally active, and potent inhibitor of tryptophan hydroxylase 1 (TPH1) that significantly reduces 5-hydroxytryptamine (5-HT) levels and decreases pulmonary arterial hypertension (PAH) at low concentrations. Target: Hydroxylase, 5-HT Receptor. Smiles:...
| Schlagworte: | KAR5585, RVT-1201, RVT-014 |
| Anwendung: | Targets tryptophan 5-monooxygenase [EC:1.14.16.4] (TPH1_2) |
| CAS | 1673571-51-1 |
| MW: | 590.04 D |
ab 2.391,00 €
Rodatristat
Artikelnummer: TGM-T16780-100mg
Description: Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively). Target: Others. Smiles: C(O)(=O)[C@@H]1CC2(CCN(CC2)C=3C=C(O[C@@H]([C@@](F)(F)F)C4=C(C=C(Cl)C=C4)C5=CC=CC=C5)N=C(N)N3)CN1. References: Goldberg DR, et al. Optimization of spirocyclic proline...
| Schlagworte: | KAR5417 |
| Anwendung: | Targets tryptophan 5-monooxygenase [EC:1.14.16.4] (TPH1_2) |
| CAS | 1673568-73-4 |
| MW: | 561.98 D |
ab 2.421,00 €
LP-533401
Artikelnummer: TGM-T15778-10mg
Description: LP-533401 is an inhibitor of Tryptophan hydroxylase 1. It is used for regulates serotonin production in the gut. Target: Hydroxylase. Smiles: N[C@@H](Cc1ccc(cc1)-c1cc(OC(c2ccc(cc2)-c2cccc(F)c2)C(F)(F)F)nc(N)n1)C(O)=O. References: Yadav, V.K., et al. Inhibition of gut-derived serotonin synthesis: A...
| Anwendung: | Tph1 inhibitor |
| CAS | 945976-43-2 |
| MW: | 526.48 D |
ab 770,00 €
Telotristat
Artikelnummer: TGM-T21506-1mg
Description: Telotristat is the active metabolite of LX1606(Telotristat etiprate), which is an orally bioavailable tryptophan hydroxylase (TPH) inhibitor and shows potential antiserotonergic activity. Target: Hydroxylase. Smiles: Cc1ccn(n1)-c1cc(Cl)ccc1[C@@H](Oc1cc(nc(N)n1)-c1ccc(C[C@H](N)C(O)=O)cc1)C(F)(F)F....
| Anwendung: | Targets tryptophan 5-monooxygenase [EC:1.14.16.4] (TPH1_2) |
| CAS | 1033805-28-5 |
| MW: | 546.93 D |
ab 31,00 €
Tryptophan 5-hydroxylase 2 (TPH2), human, recombinant
Artikelnummer: CSB-EP809000HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-490aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MQPAMMMFSS KYWARRGFSL DSAVPEEHQL LGSSTLNKPN SGKNDDKGNK GSSKREAATE SGKTAVVFSL KNEVGGLVKA LRLFQEKRVN MVHIESRKSR RRSSEVEIFV DCECGKTEFN ELIQLLKFQT...
| Schlagworte: | NTPH, TPH2, EC=1.14.16.4, Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2, Neuronal tryptophan hydroxylase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 60.1 kD |
ab 247,00 €