Zu "K00502" wurden 142 Artikel gefunden!
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Anti-TPH2 / Tryptophan hydroxylase 2, clone 31T01
Artikelnummer: NSJ-FY13043
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. TPH2 antibody detects Tryptophan hydroxylase 2, encoded by the TPH2 gene. Tryptophan hydroxylase 2 is the rate limiting enzyme in the biosynthesis of serotonin in the brain. By catalyzing the...
| Schlagworte: | Anti-TPH2, Anti-Tryptophan 5-hydroxylase 2, Anti-Tryptophan 5-monooxygenase 2, Anti-Neuronal tryptophan hydroxylase, TPH2... |
| Anwendung: | WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
790,00 €
TPH1
Artikelnummer: BPS-71192
Human tryptophan 5- hydroxylase 1 (TPH1) also known as TRPH, GenBank Accession No. NM_004179, a.a. 105-420 with an N-terminal His-tag, MW = 37 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | TPH, TPH1, Tryptophan 5-hydroxylase 1, Tryptophan 5-monooxygenase 1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 37 kD |
506,00 €
TPH2
Artikelnummer: BPS-71193
Human tryptophan hydroxylase 2 (TPH2) also known as neuronal tryptophan hydroxylase, GenBank Accession No. NM_173353, a.a. 151-466 (end) with an N-terminal His-tag, MW = 37 kDa, expressed in an E. coli cell expression system.
| Schlagworte: | TPH2, NTPH, EC=1.14.16.4, Tryptophan 5-hydroxylase 2, Tryptophan 5-monooxygenase 2, Neuronal tryptophan hydroxylase, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
| MW: | 37 kD |
506,00 €
TPH1 Inhibitor Screening Assay Kit
Artikelnummer: BPS-72053
The TPH1 Assay Kit is designed to measure TPH1 enzyme inhibition in a 96 reaction format. This fluorescence-based assay kit is especially suitable for high throughput screening applications. The procedure is quick, straightforward, and simple just mix two solutions, incubate, add quenching solution, and measure the...
| Schlagworte: | tryptophan 5-hyrdoxylase, TRPH, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.241,00 €
TPH2 Inhibitor Screening Assay Kit
Artikelnummer: BPS-72054
The TPH2 Assay Kit is designed to measure TPH2 enzyme inhibition in a 96 reaction format. This fluorescence-based assay kit is especially suitable for high throughput screening applications. The procedure is quick, straightforward, and simple just mix two solutions, incubate, add quenching solution, and measure the...
| Schlagworte: | tryptophan 5-hyrdoxylase, TRPH, |
| Anwendung: | Drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.241,00 €
Telotristat Etiprate
Artikelnummer: Cay25342-5
Telotristat etiprate is a prodrug form of telotristat, which is an inhibitor of tryptophan hydroxylase 1 (TPH1). Telotristat etiprate (15-300 mg/kg) reduces levels of serotonin (5-HT, Cay-14332) in mouse jejunum and blood but not brain. It inhibits increases in IL-1beta and IL-6 levels, histological damage in the...
| Schlagworte: | LX 1032 hippurate, LX 1606 hippurate,... |
| Anwendung: | TPH1 inhibitor prodrug |
| CAS | 1137608-69-5 |
| MW: | 754.2 D |
ab 139,00 €
6-fluoro-DL-Tryptophan
Artikelnummer: Cay17643-50
Tryptophan is an amino acid precursor of serotonin (Cay-14332) and melatonin (Cay-14427). 6-fluoro-DL-Tryptophan is a serotonin synthesis inhibitor that is metabolized in the brain and may be useful for tracing pools of neuronal serotonin. It is used as a competitive inhibitor of tryptophan binding to albumin and...
| Schlagworte: | DL-6-Fluorotryptophan, NSC 9364, 6-fluoro-tryptophan |
| Anwendung: | Serotonin synthesis inhibitor |
| CAS | 7730-20-3 |
| MW: | 222.2 D |
ab 67,00 €
Telotristat
Artikelnummer: Cay29424-10
Telotristat is a tryptophan hydroxylase 1 (TPH1) inhibitor (IC50 = 16 nM). Dietary administration of telotristat to pregnant and lactating mice decreases serotonin (5-HT, Cay-14332) levels in maternal serum and decreases the femoral bone volume to tissue volume ratio, trabecular number and thickness, and cortical...
| Schlagworte: | LP778902,... |
| Anwendung: | TPH1 inhibitor |
| CAS | 1033805-28-5 |
| MW: | 546.9 D |
ab 128,00 €
p-chloro Phenylalanine
Artikelnummer: Cay26168-10
p-chloro Phenylalanine is an inhibitor of tryptophan hydroxylase (Ki = 300 µM). It acts as a competitive inhibitor in vitro and an irreversible inhibitor in vivo. It depletes serotonin to undetectable levels in rats after six days when administered at a dose of 300 mg/kg. p-chloro Phenylalanine has commonly been...
| Schlagworte: | para-chloro Phenylalanine, 4-chloro Phenylalanine, CP 10188, Fenclonine, NSC 77370, PCPA, 4-chloro-phenylalanine |
| Anwendung: | Tryptophan hydroxylase inhibitor |
| CAS | 7424-00-2 |
| MW: | 199.6 D |
ab 60,00 €
Anti-Tryptophan hydroxylase 2 / TPH2, Internal
Artikelnummer: ARG63844.100
| Schlagworte: | Anti-NTPH, Anti-TPH2, EC=1.14.16.4, Anti-Tryptophan 5-hydroxylase 2, Anti-Tryptophan 5-monooxygenase 2, Anti-Neuronal... |
| Anwendung: | ELISA, IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Telotristat
Artikelnummer: BPS-27340
Telotristat is the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
| Schlagworte: | LX1032, |
| Anwendung: | Tryptophan hydroxylase (TPH) inhibitor |
| MW: | 547 D |
550,00 €
Telotristat
Artikelnummer: BPS-27341
Telotristat is the active metabolite of LX1606 (Telotristat etiprate), which is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
| Schlagworte: | LX1032, |
| Anwendung: | Tryptophan hydroxylase (TPH) inhibitor |
| MW: | 547 D |
912,00 €