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Zu "K00486" wurden 49 Artikel gefunden!
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Artikelnummer: TGM-TMPH-01595-100ug
Description: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain...
Schlagworte: | Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, KMO |
MW: | 61.9 kD |
ab 198,00 €
Artikelnummer: TGM-T1896-100mg
Description: Ro 61-8048 is a potent and selective inhibitor of kynurenine hydroxylase with an IC50 value of 37 nM. Target: Hydroxylase. Smiles: COc1ccc(cc1OC)S(=O)(=O)Nc1nc(cs1)-c1cccc(c1)[N+]([O-])=O. References: Röver S, et al. J Med Chem. 1997, 40(26), 4378-4385.
Anwendung: | Kynurenine 3-hydroxylase inhibitor |
CAS | 199666-03-0 |
MW: | 421.45 D |
ab 34,00 €
Artikelnummer: TGM-T13258L-2mg
Description: UPF-648 is a potent kynurenine 3-monooxygenase (KMO) inhibitor, demonstrating high activity at 1 µM with 81 ± 10% inhibition. Target: Others. Smiles: OC(=O)[C@H]1C[C@@H]1C(=O)c1ccc(Cl)c(Cl)c1
Anwendung: | Kynurenine 3-monooxygenase inhibitor |
CAS | 213400-34-1 |
MW: | 259.09 D |
34,00 €
Artikelnummer: CSB-EP012475HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-486aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MDSSVIQRKK VAVIGGGLVG SLQACFLAKR NFQIDVYEAR EDTRVATFTR GRSINLALSH RGRQALKAVG LEDQIVSQGI PMRARMIHSL SGKKSAIPYG TKSQYILSVS RENLNKDLLT AAEKYPNVKM...
Schlagworte: | Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, Recombinant Human Kynurenine 3-monooxygenase (KMO) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 71.8 kD |
ab 219,00 €
Artikelnummer: CSB-EP012475HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-486aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MDSSVIQRKK VAVIGGGLVG SLQACFLAKR NFQIDVYEAR EDTRVATFTR GRSINLALSH RGRQALKAVG LEDQIVSQGI PMRARMIHSL SGKKSAIPYG TKSQYILSVS RENLNKDLLT AAEKYPNVKM...
Schlagworte: | Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, Recombinant Human Kynurenine 3-monooxygenase (KMO) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 61.8 kD |
ab 219,00 €
Artikelnummer: CSB-EP012475HUb0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-486aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged. Target Protein Sequence: MDSSVIQRKK VAVIGGGLVG SLQACFLAKR NFQIDVYEAR EDTRVATFTR GRSINLALSH RGRQALKAVG LEDQIVSQGI PMRARMIHSL SGKKSAIPYG TKSQYILSVS RENLNKDLLT AAEKYPNVKM...
Schlagworte: | Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, Recombinant Human Kynurenine 3-monooxygenase (KMO) |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 61.9 kD |
ab 219,00 €
Artikelnummer: CSB-EP012475RA.1
Organism: Rattus norvegicus (Rat). Source: E.coli. Expression Region: 1-384aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: MASSDTEGKR VVVIGGGLVG ALNACFLAKR NFQVDVYEAR EDIRVANFMR GRSINLALSY RGRQALKAVG LEDQIVSKGV PMKARMIHSL SGKKSAIPYG NKSQYILSIS REKLNKDLLT AVESYPNAKV...
Schlagworte: | Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, Recombinant Rat Kynurenine 3-monooxygenase (Kmo), partial |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | rat |
MW: | 59.5 kD |
ab 364,00 €
Artikelnummer: CSB-YP012475HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-486aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MDSSVIQRKK VAVIGGGLVG SLQACFLAKR NFQIDVYEAR EDTRVATFTR GRSINLALSH RGRQALKAVG LEDQIVSQGI PMRARMIHSL SGKKSAIPYG TKSQYILSVS RENLNKDLLT AAEKYPNVKM HFNHRLLKCN...
Schlagworte: | Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, Recombinant Human Kynurenine 3-monooxygenase (KMO) |
Anwendung: | Activity not tested |
Exprimiert in: | Yeast |
Ursprungsart: | human |
MW: | 57.8 kD |
ab 242,00 €
Artikelnummer: Cay15199-5
The kynurenine pathway mediates the metabolism of L-tryptophan to NAD+ and is particularly important in neurophysiology. Ro 61-8048 is a potent inhibitor of kynurenine 3-hydroxylase (IC50 = 37 nM), preventing the conversion of kynurenine (Cay-11305) to 3-hydroxy kynurenine. Ro 61-8048 inhibition of kynurenine...
Schlagworte: | 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]-benzenesulfonamide |
Anwendung: | Kynurenine 3-hydroxylase inhibitor |
CAS | 199666-03-0 |
MW: | 421.4 D |
ab 111,00 €
Artikelnummer: 600-401-J25
Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards Kynurenine 3-monooxygenase (KMO). A BLAST analysis was used to suggest cross-reactivity with Mouse based on 100% sequence homology. Cross-reactivity with KMO from other sources has not been...
Schlagworte: | Anti-KMO, EC=1.14.13.9, Anti-Kynurenine 3-hydroxylase, Anti-Kynurenine 3-monooxygenase |
Anwendung: | ELISA, IHC, IFM, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse, human |
719,00 €
Artikelnummer: 600-401-J26
Anti-KMO was affinity purified from monospecific antiserum by immunoaffinity chromatography. This antibody is specific towards Kynurenine 3-monooxygenase (KMO). A BLAST analysis was used to suggest cross-reactivity with Mouse based on 100% sequence homology. Cross-reactivity with KMO from other sources has not been...
Schlagworte: | Anti-KMO, EC=1.14.13.9, Anti-Kynurenine 3-hydroxylase, Anti-Kynurenine 3-monooxygenase |
Anwendung: | ELISA, IHC, IFM, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
719,00 €
Artikelnummer: LKT-R5700.25
Kynurenine 3-hydroxylase inhibitor.
Anwendung: | Kynurenine 3-hydroxylase inhibitor |
CAS | 199666-03-0 |
MW: | 421.44 D |
ab 175,00 €