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Zu "K00471" wurden 19 Artikel gefunden!
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Artikelnummer: Cay15997-10
Mildronate is a structural analog of gamma-butyrobetaine (gammaBB), an intermediate in the biosynthesis of carnitine. It blocks carnitine synthesis by inhibiting gammaBB hydroxylase (IC50 = 62 µM) and, less potently, carnitine acetyltransferase (Ki = 1.6 mM). Through these actions, mildronate reduces the levels of...
| Schlagworte: | Meldonium, MET-88, Quaterine, THP, 2-(2-carboxyethyl)-1,1,1-trimethyl-hydrazinium inner salt, dihydrate |
| Anwendung: | gamma-butyrobetaine dioxygenase inhibitor, carnitine synthesis inhibitor |
| CAS | 86426-17-7 |
| MW: | 182.2 D |
ab 52,00 €
Artikelnummer: ARG41028.100
Protein function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine. [The UniProt Consortium]
| Schlagworte: | Anti-BBH, Anti-BBOX1, Anti-Gamma-BBH, EC=1.14.11.1, Anti-Gamma-butyrobetaine dioxygenase, Anti-Gamma-butyrobetaine... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Artikelnummer: E-AB-18533.120
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation....
| Schlagworte: | Anti-BBH, Anti-BBOX1, Anti-Gamma-BBH, EC=1.14.11.1, Anti-Gamma-butyrobetaine hydroxylase, Anti-Gamma-butyrobetaine... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: E-AB-52465.120
This gene encodes gamma butyrobetaine hydroxylase which catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport of activated fatty acids across the mitochondrial membrane during mitochondrial beta-oxidation....
| Schlagworte: | Anti-BBH, Anti-BBOX1, Anti-Gamma-BBH, EC=1.14.11.1, Anti-Gamma-butyrobetaine hydroxylase, Anti-Gamma-butyrobetaine... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: ATA-HPA007600.100
Protein function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 95%
| Schlagworte: | Anti-BBH, Anti-BBOX1, Anti-Gamma-BBH, EC=1.14.11.1, Anti-Gamma-butyrobetaine hydroxylase, Anti-Gamma-butyrobetaine... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Artikelnummer: CSB-EP530450HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-387aa. Protein Length: Full Length. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MACTIQKAEA LDGAHLMQIL WYDEEESLYP AVWLRDNCPC SDCYLDSAKA RKLLVEALDV NIGIKGLIFD RKKVYITWPD EHYSEFQADW LKKRCFSKQA RAKLQRELFF...
| Schlagworte: | BBH, BBOX1, Gamma-BBH, EC=1.14.11.1, Gamma-butyrobetaine hydroxylase, Gamma-butyrobetaine dioxygenase,... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 52.2 kD |
ab 292,00 €
Artikelnummer: TGM-TMPY-03756-100ug
Description: BBOX1, also known as gamma-BBH, belongs to thegamma-BBH/TMLD family. It is highly expressed in kidney and moderately expressed in liver. BBOX1 catalyzes the formation of L-carnitine from gamma-butyrobetaine, the last step in the L-carnitine biosynthetic pathway. Carnitine is essential for the transport...
| Schlagworte: | G-BBH, gamma-BBH, gamma-BBH, BBH, BBOX, butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine... |
| MW: | 72.5 kD |
768,00 €
Artikelnummer: TGM-T6586-1mL
Description: Mildronate dihydrate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption. Target: Others, Mitochondrial Metabolism. Smiles: O.O.C[N+](C)(C)NCCC([O-])=O. References: Simkhovich BZ, et al. Biochem...
| Schlagworte: | Meldonium , Mildronate |
| Anwendung: | gamma-butyrobetaine dioxygenase inhibitor, carnitine synthesis inhibitor |
| CAS | 86426-17-7 |
| MW: | 182.22 D |
ab 29,00 €
NEU
Artikelnummer: G-AGMB06275.100
BBOX1 Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Catalyzes the formation of L-carnitine from gamma-butyrobetaine [The Uniprot Consortium]
| Schlagworte: | Anti-BBOX1, Anti-Gamma-butyrobetaine hydroxylase, Anti-Gamma-butyrobetaine dioxygenase,... |
| Anwendung: | IHC-P |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 353,00 €
Artikelnummer: CSB-PA615182XA01CXY.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | Anti-gbh-1, Anti-D2089.5, Anti-Gamma-BBH, EC=1.14.11.1, Anti-Gamma-butyrobetaine hydroxylase, Anti-Probable... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Caenorhabditis elegans |
ab 1.529,00 €
Artikelnummer: ATA-APrEST71303.100
Protein function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine. [The UniProt Consortium] Buffer: PBS and 1M Urea, pH 7.4.
| Schlagworte: | BBH, BBOX1, Gamma-BBH, EC=1.14.11.1, Gamma-butyrobetaine hydroxylase, Gamma-butyrobetaine dioxygenase,... |
| Anwendung: | Control antigen |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
264,00 €
Artikelnummer: G-CAB5810.20
Protein function: Catalyzes the formation of L-carnitine from gamma- butyrobetaine. [The UniProt Consortium]
| Schlagworte: | Anti-BBH, Anti-BBOX1, Anti-Gamma-BBH, EC=1.14.11.1, Anti-Gamma-butyrobetaine hydroxylase, Anti-Gamma-butyrobetaine... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
103,00 €