Zu "K00461" wurden 98 Artikel gefunden!
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Oleacein
Artikelnummer: Cay40719-1
Oleacein is a secoiridoid polyphenol that has been found in O. europea and has diverse biological activities. It inhibits 5-lipoxygenase (5-LO, IC50 = 2 µM for the human enzyme). Oleacein (20 and 50 µM) reduces lipid accumulation and inhibits the transition into foam cells in human monocyte-derived macrophages. It...
| Schlagworte: | (3S,4E)-4-formyl-3-(2-oxoethyl)-4-hexenoic acid, 2-(3,4-dihydroxyphenyl) ethyl ester |
| Anwendung: | Bioactive secoiridoid polyphenol, weak 5-LO inhibitor |
| CAS | 149183-75-5 |
| MW: | 320.3 D |
ab 133,00 €
Anti-ALOX5
Artikelnummer: CSB-PA043268.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALOX5. Antigen Species: Human
| Schlagworte: | Anti-5-LO, Anti-LOG5, Anti-5-lipoxygenase, Anti-Arachidonate 5-lipoxygenase, Anti-Polyunsaturated fatty acid... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Anti-ALOX5 Recombinant Monoclonal, clone 1D4
Artikelnummer: CSB-RA198316A0HU.100
Isotype: Rabbit IgG. Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity-chromatography. Target Name: ALOX5. Antigen Species: Human
| Schlagworte: | Anti-5-LO, Anti-LOG5, Anti-5-lipoxygenase, Anti-Arachidonate 5-lipoxygenase, Anti-Polyunsaturated fatty acid... |
| Anwendung: | ELISA, WB, IHC, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 201,00 €
Anti-Phospho-ALOX5 (Ser523)
Artikelnummer: CSB-PA555261.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-5-LO, Anti-phospho-LOG5, Anti-phospho-5-lipoxygenase, Anti-phospho-Arachidonate 5-lipoxygenase,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
330,00 €
Anti-ALOX5
Artikelnummer: CSB-PA787659.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: ALOX5. Antigen Species: Human
| Schlagworte: | Anti-5-LO, Anti-LOG5, Anti-5-lipoxygenase, Anti-Arachidonate 5-lipoxygenase, Anti-Polyunsaturated fatty acid... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 163,00 €
Zileuton
Artikelnummer: Cay10006967-50
Zileuton is a reversible 5-lipoxygenase (5-LO) inhibitor. It inhibits 5-LO activity in rat basophilic leukemia-1 (RBL-1) cell supernatant with an IC50 value of 0.5 µM. Zileuton inhibits leukotriene B4 (LTB4, Cay-20110) production induced by the calcium ionophore A23187 (Cay-11016) in purified human peripheral blood...
| Schlagworte: | A 64077, N-(1-benzo[b]thien-2-ylethyl)-N-hydroxy-urea |
| Anwendung: | 5-LO inhibitor |
| CAS | 111406-87-2 |
| MW: | 236.3 D |
ab 28,00 €
Stearda
Artikelnummer: Cay38973-10
Stearda is an endogenous fatty acid amide composed of the catecholamine dopamine (Cay-36532, Cay-21992) conjugated to the long-chain saturated fatty acid stearic acid (Cay-10011298). It is an inhibitor of 5-lipoxygenase (5-LO, IC50 = 16 nM). Stearda is cytotoxic to K562 chronic myeloid leukemia cells, HOS...
| Schlagworte: | N-octadecanoyl Dopamine, N-Stearoyl Dopamine, N-[2-(3,4-dihydroxyphenyl)ethyl]-octadecanamide |
| Anwendung: | Endogenous fatty acid amide, arachidonate 5-lipoxygenase inhibitor |
| CAS | 105955-10-0 |
| MW: | 419.6 D |
ab 88,00 €
MK-886 (sodium salt)
Artikelnummer: Cay10133-5
Arachidonic acid (Cay-90010) and selected other polyunsaturated fatty acids are stereoselectively oxygenated at carbon 5 by the non-heme iron containing enzyme 5-lipoxygenase (5-LO). The intervention of a second protein, 5-LO-activating protein (FLAP), is required before 5-LO can become catalytically active. MK-886...
| Schlagworte: | 1-[(4-chlorophenyl)methyl]-3-[(1,1-dimethylethyl)thio]-alpha,alpha-dimethyl-5-(1-methylethyl)-1H-indole-2-propanoic acid,... |
| Anwendung: | Leukotriene biosynthesis inhibitor |
| CAS | 118427-55-7 |
| MW: | 494.1 D |
ab 43,00 €
Mouse ALOX5 (Arachidonate-5-Lipoxygenase) ELISA Kit
Artikelnummer: ELK-ELK3188.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ALOX5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ALOX5. Next,...
| Schlagworte: | 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase, Polyunsaturated fatty acid 5-lipoxygenase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human ALOX5 (Arachidonate-5-Lipoxygenase) ELISA Kit
Artikelnummer: ELK-ELK1892.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ALOX5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ALOX5. Next,...
| Schlagworte: | 5-LO, LOG5, 5-lipoxygenase, Arachidonate 5-lipoxygenase, Polyunsaturated fatty acid 5-lipoxygenase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat ALOX5 (Arachidonate-5-Lipoxygenase) ELISA Kit
Artikelnummer: ELK-ELK5763.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ALOX5. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ALOX5. Next,...
| Schlagworte: | 5-LO, 5-lipoxygenase, Arachidonate 5-lipoxygenase, Polyunsaturated fatty acid 5-lipoxygenase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
5-Lipoxygenase (human, recombinant)
Artikelnummer: Cay60402-5
5-Lipoxygenase (5-LO) is an enzyme encoded by ALOX5 in humans that is involved in leukotriene biosynthesis. It is composed of an N-terminal regulatory domain and a C-terminal catalytic domain and is primarily expressed in leukocytes. Increases in intracellular calcium levels or cellular stress induce translocation...
| Schlagworte: | LOG5, 5-LO, 5-LO, 5-lipoxygenase, 5-lipoxygenase, Arachidonate 5-lipoxygenase, Arachidonate 5-lipoxygenase,... |
| Anwendung: | Enzyme activity |
642,00 €