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Zu "K00460" wurden 44 Artikel gefunden!
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Artikelnummer: ELK-ELK4753.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ALOX15. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ALOX15....
Schlagworte: | LOG15, 15-LOX, 12-LOX, 15-LOX-1, 12/15-lipoxygenase, Linoleate 13S-lipoxygenase, Hepoxilin A3 synthase Alox15,... |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay38946-10
ThioLox is an inhibitor of 15-lipoxygenase 1 (15-LO-1, Ki = 3.3 µM). It also is an inhibitor of P. falciparum aspartate carbamoyltransferase (IC50 = 3.32 µM). ThioLox (50 µM) reduces LPS-induced expression of the mRNAs encoding TNF-alpha, inducible nitric oxide synthase (iNos), Il-1beta, Il-6, Il-8, and Il-12b in...
Schlagworte: | 2-amino-N-butyl-5-phenyl-3-thiophenecarboxamide |
Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
CAS | 1202193-89-2 |
MW: | 274.4 D |
ab 77,00 €
Artikelnummer: Cay11182-10
Resolvin D1-d5 (RvD1-d5) is intended for use as an internal standard for the quantification of RvD1 (Cay-10012554) by GC- or LC-mass spectrometry. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being...
Schlagworte: | 17(S)-Resolvin D1-d5, RvD1-d5, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-21,21',22,22,22-d5 docosahexaenoic acid |
Anwendung: | GC-MS, LC-MS, Internal standard |
CAS | 1881277-32-2 |
MW: | 381.5 D |
ab 226,00 €
Artikelnummer: Cay10004161-10
Luteolin is a polyphenolic flavone found in many plants including soybeans and perilla leaves. Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM. Luteolin has also been found to inhibit the release of TNFalpha from neutrophils, and to inhibit...
Schlagworte: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
Anwendung: | 15-LO inhibitor |
CAS | 491-70-3 |
MW: | 286.2 D |
ab 34,00 €
Artikelnummer: Cay16119-5
Lipoxygenases (LOs) are non-heme iron-containing dioxygenases that catalyze the oxidation of polyunsaturated fatty acids to generate unsaturated fatty acid hydroperoxides. The immediate products of 15-LO fatty acid oxidation act as mediators in inflammation, thrombosis, and cancer. ML-351 is an inhibitor of human...
Schlagworte: | CID 664510, 5-(methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile |
Anwendung: | 15-LO-1 inhibitor |
CAS | 847163-28-4 |
MW: | 249.3 D |
ab 76,00 €
Artikelnummer: Cay10010518-5
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total...
Schlagworte: | NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole |
Anwendung: | 15-LO inhibitor |
CAS | 4079-26-9 |
MW: | 237.3 D |
ab 65,00 €
Artikelnummer: Cay29590-10
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) by 15-lipoxygenase (15-LO) via 15(S)-HpEPE (Cay-42710) and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human...
Schlagworte: | RvE4, 5S,15S-dihydroxy-6E,8Z,11Z,13E,17Z-eicosapentaenoic acid |
Anwendung: | Specialized pro-resolving mediator (SPM) |
CAS | 1781227-87-9 |
MW: | 334.5 D |
ab 163,00 €
Artikelnummer: Cay70300-500
NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis. NDGA inhibits A-23187-induced CysLT biosynthesis in rat peritoneal cells with an IC50 value of 5-7 µM. The IC50 values are 3.0-5.0 µM for human platelet 12-LO and 0.91 µM for rabbit reticulocyte 15-LO.Formal...
Schlagworte: | NDGA, NSC 4291, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-1,2-benzenediol |
Anwendung: | Non-selective lipoxygenase (LO) inhibitor |
CAS | 500-38-9 |
MW: | 302.4 D |
ab 48,00 €
Artikelnummer: AG-CN2-0098-M005
Yellow solid. Soluble in DMSO, DMF, methanol or ethanol. Slightly soluble in water. Anticancer and antimetastatic, alpha-Glucosidase inhibitor, Topoisomerase I Inhibitor, Apoptosis inducer, Anti-inflammatory, 15-Lipoxygenase (15-LOX) inhibitor, IL-6 production inhibitor, Fatty acid synthase (FAS) inhibitor,...
Schlagworte: | 3',4',5,7-Tetrahydroxyflavone, Luteolol, BRN 0292084, C.I. Natural Yellow 2, Digitoflavone, Flacitran, Flavopurpol,... |
Anwendung: | 15-LOX inhibitor |
CAS | 491-70-3 |
MW: | 286,2 D |
ab 17,00 €
Artikelnummer: Cay27391-5
BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1, IC50 = 32 nM in a cell-free enzyme assay). It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over...
Schlagworte: | 15-LO-1 Inhibitor 3887, 4,5-dichloro-N-(2-chloro-4-fluorophenyl)-1H-pyrazole-3-carboxamide |
Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
CAS | 934758-70-0 |
MW: | 308.5 D |
ab 43,00 €
Artikelnummer: BPS-50220
ALOX-15, also known as 15LOX-1, omega-6 lipoxygenase, or arachidonate 15-lipoxygenase (GenBank Accession No. NM_001140), a.a. 2- 662(end), with N-terminal FLAG-tag, MW=75 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
Schlagworte: | LOG15, 12-LOX, 15-LOX, 15-LOX-1, 12/15-lipoxygenase, Linoleate 13S-lipoxygenase, Hepoxilin A3 synthase Alox15,... |
MW: | 75 kD |
825,00 €
Artikelnummer: Cay25856-100
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Cay-10011298) at the sn-1 position and 15(S)-HpETE (Cay-44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE, Cay-25871) by 15-lipoxygenase (15-LO)....
Schlagworte: | 15(S)-HpETE-SAPE, 15(S)-hydroperoxyeicostetraenoic acid-SAPE, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine,... |
Anwendung: | Phospholipid |
CAS | 154436-49-4 |
MW: | 800.1 D |
ab 158,00 €