Zu "K00460" wurden 63 Artikel gefunden!
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Anti-Recombinant ALOX15, clone A127
Artikelnummer: E-AN301432L.100
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on various polyunsaturated fatty acid substrates to generate various bioactive lipid mediators such as eicosanoids, hepoxilins, lipoxins, and other molecules. The encoded enzyme and its reaction products have been shown to...
| Schlagworte: | Anti-ALOX15, Anti-12/15-lipoxygenase, Anti-Linoleate 13S-lipoxygenase, Anti-Arachidonate 15-lipoxygenase, Anti-Hepoxilin... |
| Anwendung: | IHC, IF, FCM |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, african green monkey |
ab 304,00 €
Resolvin D1-d5
Artikelnummer: Cay11182-10
Resolvin D1-d5 (RvD1-d5) is intended for use as an internal standard for the quantification of RvD1 (Cay-10012554) by GC- or LC-mass spectrometry. Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being...
| Schlagworte: | 17(S)-Resolvin D1-d5, RvD1-d5, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-21,21',22,22,22-d5 docosahexaenoic acid |
| Anwendung: | GC-MS, LC-MS, internal standard |
| CAS | 1881277-32-2 |
| MW: | 381.5 D |
ab 302,00 €
Luteolin
Artikelnummer: Cay10004161-10
Luteolin is a polyphenolic flavone found in many plants including soybeans and perilla leaves. Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM. Luteolin has also been found to inhibit the release of TNFalpha from neutrophils, and to inhibit...
| Schlagworte: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one |
| Anwendung: | 15-LO inhibitor |
| CAS | 491-70-3 |
| MW: | 286.2 D |
ab 44,00 €
PD 146176
Artikelnummer: Cay10010518-5
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1. It limits hypercholesterolemia-induced atherosclerosis in New Zealand White rabbits and reduces oxidant stress-induced apoptosis in endothelial cells. PD 146176 inhibits amyloid beta protein aggregate formation without changing total...
| Schlagworte: | NSC 168807, 6,11-dihydro-[1]benzothiopyrano[4,3-b]indole |
| Anwendung: | 15-LO inhibitor |
| CAS | 4079-26-9 |
| MW: | 237.3 D |
ab 72,00 €
Resolvin E4
Artikelnummer: Cay29590-10
Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) by 15-lipoxygenase (15-LO) via 15(S)-HpEPE (Cay-42710) and 15S-hydroxy, 5S-HpEPE intermediates in vitro and by isolated human...
| Schlagworte: | RvE4, 5S,15S-dihydroxy-6E,8Z,11Z,13E,17Z-eicosapentaenoic acid |
| Anwendung: | Specialized pro-resolving mediator (SPM) |
| CAS | 1781227-87-9 |
| MW: | 334.5 D |
ab 181,00 €
Luteolin
Artikelnummer: AG-CN2-0098-M005
Yellow solid. Soluble in DMSO, DMF, methanol or ethanol. Slightly soluble in water. Anticancer and antimetastatic, alpha-Glucosidase inhibitor, Topoisomerase I Inhibitor, Apoptosis inducer, Anti-inflammatory, 15-Lipoxygenase (15-LOX) inhibitor, IL-6 production inhibitor, Fatty acid synthase (FAS) inhibitor,...
| Schlagworte: | 3',4',5,7-Tetrahydroxyflavone, Luteolol, BRN 0292084, C.I. Natural Yellow 2, Digitoflavone, Flacitran, Flavopurpol,... |
| Anwendung: | 15-LOX inhibitor |
| CAS | 491-70-3 |
| MW: | 286,2 D |
ab 22,00 €
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
Artikelnummer: Cay26531-100
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Cay-10011298) at the sn-1 position and 15(S)-HpETE (Cay-44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC, Cay-10009864) by 15-lipoxygenase (15-LO)....
| Schlagworte: | 15(S)-HpETE-SAPC, 15(S)-Hydroperoxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Phosphatidylcholine,... |
| Anwendung: | Phospholipid, SAPC oxidation product |
| CAS | 154436-48-3 |
| MW: | 842.1 D |
ab 174,00 €
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
Artikelnummer: Cay25856-100
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Cay-10011298) at the sn-1 position and 15(S)-HpETE (Cay-44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE, Cay-25871) by 15-lipoxygenase (15-LO)....
| Schlagworte: | 15(S)-HpETE-SAPE, 15(S)-hydroperoxyeicostetraenoic acid-SAPE, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine,... |
| Anwendung: | Phospholipid |
| CAS | 154436-49-4 |
| MW: | 800.1 D |
ab 186,00 €
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
Artikelnummer: Cay21138-100
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Cay-10011298) at the sn-1 position and 15(S)-HETE (Cay-34720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC, Cay-10009864) by 15-lipoxygenase (15-LO).Formal Name:...
| Schlagworte: | 15(S)-HETE-SAPC, 15(S)-Hydroxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylcholine,... |
| Anwendung: | Phospholipid |
| CAS | 154436-51-8 |
| MW: | 826.1 D |
ab 147,00 €
BLX3887
Artikelnummer: Cay27391-1
BLX3887 is an inhibitor of 15-lipoxygenase type 1 (15-LO-1, IC50 = 32 nM in a cell-free enzyme assay). It is selective for 15-LO-1 over 15-LO-2, which it does not inhibit, 5-LO (IC50 = 472 nM), and 12-LO (IC50 = 3,310 nM). BLX3887 inhibits the production of 15-LO metabolites selectively in eosinophils over...
| Schlagworte: | 15-LO-1 Inhibitor 3887, 4,5-dichloro-N-(2-chloro-4-fluorophenyl)-1H-pyrazole-3-carboxamide |
| Anwendung: | 15-LOX-1 (ALOX15) inhibitor |
| CAS | 934758-70-0 |
| MW: | 308.5 D |
ab 49,00 €
Nordihydroguaiaretic Acid
Artikelnummer: Cay70300-500
NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis. NDGA inhibits A-23187-induced CysLT biosynthesis in rat peritoneal cells with an IC50 value of 5-7 µM. The IC50 values are 3.0-5.0 µM for human platelet 12-LO and 0.91 µM for rabbit reticulocyte 15-LO.Formal...
| Schlagworte: | NDGA, NSC 4291, 4,4'-(2,3-dimethyl-1,4-butanediyl)bis-1,2-benzenediol |
| Anwendung: | Non-selective lipoxygenase (LO) inhibitor |
| CAS | 500-38-9 |
| MW: | 302.4 D |
ab 54,00 €
ALOX15, FLAG-tag, human recombinant protein
Artikelnummer: BPS-50220
ALOX-15, also known as 15LOX-1, omega-6 lipoxygenase, or arachidonate 15-lipoxygenase (GenBank Accession No. NM_001140), a.a. 2- 662(end), with N-terminal FLAG-tag, MW=75 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | LOG15, 12-LOX, 15-LOX, 15-LOX-1, 12/15-lipoxygenase, Linoleate 13S-lipoxygenase, Hepoxilin A3 synthase Alox15,... |
| MW: | 75 kD |
842,00 €