Zu "K00355" wurden 87 Artikel gefunden!
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NEU
NQO1 Protein, Mouse, Recombinant (His)
Artikelnummer: TGM-TMPH-02797-10ug
Description: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 Protein, Mouse,...
| Schlagworte: | Nmo1 , Azoreductase , Nqo1 , Phylloquinone reductase , Dia4 , NAD(P)H dehydrogenase [quinone] 1 , DT-diaphorase (DTD) ,... |
| MW: | 32.8 kD |
ab 118,00 €
Anti-Recombinant NQO1, clone 11B3
Artikelnummer: E-AN300988L.100
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of...
| Schlagworte: | Anti-NQO1, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Quinone reductase 1, Anti-Menadione reductase, Anti-Phylloquinone... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-NQO1
Artikelnummer: NSJ-RQ8937
0.5mg/ml if reconstituted with 0.2ml sterile DI water. NAD(P)H:quinone oxidoreductase 1 (NQO1) is a cytosolic flavoprotein that plays a central role in cellular defense against oxidative stress. As a 2-electron reductase, NQO1 catalyzes the reduction of quinones to hydroquinones, thereby preventing the formation of...
| Schlagworte: | Anti-NQO1, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Quinone reductase 1, Anti-Menadione reductase, Anti-Phylloquinone... |
| Anwendung: | WB, IF, IHC (paraffin), FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-NQO1 Monoclonal Recombinant Antibody
Artikelnummer: E-AN300158P.100
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 1-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of...
| Schlagworte: | QR1, DTD, DIA4, Azoreductase, DT-diaphorase, Quinone reductase 1, Menadione reductase, Phylloquinone reductase,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
462,00 €
Pronqodine A
Artikelnummer: Cay43836-1
A quinone with enzyme inhibitory and anti-inflammatory activities, inhibits NQO1 (IC50 = 131.5 nM), inhibits bradykinin-induced PGE2, 6-keto PGF1alpha, and PGD2 production in SW 982 cells (IC50s = 9, 19, and 7 nM, respectively), induces ROS production in SW 982 cells. Formulation: A powder. InChI:...
| Schlagworte: | 5-(methylamino)-1,2-benzisothiazole-4,7-dione |
| Anwendung: | Bioactive quinone |
| CAS | 1424195-39-0 |
| MW: | 194.21 D |
779,00 €
N-Benzyl-N-demethylpronqodine A
Artikelnummer: Cay43832-1
An NQO1 inhibitor (IC50 = 83.3 nM). Formulation: A powder. InChI: InChI=1S/C14H10N2O2S/c17-12-6-11(13(18)10-8-16-19-14(10)12)15-7-9-4-2-1-3-5-9/h1-6,8,15H,7H2. InChIKey: REQNSASITZCQGJ-UHFFFAOYSA-N. SMILES: O=C1C=C(C(C2=C1SN=C2)=O)NCC3=CC=CC=C3
| Schlagworte: | 5-(Benzylamino)-1,2-benzisothiazole-4,7-dione, 5-[(phenylmethyl)amino]-1,2-benzisothiazole-4,7-dione |
| Anwendung: | NQO1 inhibitor |
| CAS | 1810092-90-0 |
| MW: | 270.31 D |
1.075,00 €
beta-Lapachone
Artikelnummer: Cay15021-5
beta-Lapachone is a natural quinone with diverse anti-cancer and anti-inflammatory effects. It inhibits topoisomerase I at 25 µM and transglutaminase (IC50 = 5 µM). In cancer cells which overexpress NAD(P)H:quinone oxidoreductase, beta-lapachone is reduced to beta-lapachone hydroquinone, which generates reactive...
| Schlagworte: | ARQ 501, NSC 26326, NSC 629749, SL 11001, 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione |
| Anwendung: | Topoisomerase I and transglutaminase inhibitor |
| CAS | 4707-32-8 |
| MW: | 242.3 D |
ab 108,00 €
Diminutol
Artikelnummer: Cay18237-1
Diminutol is a cell-permeable purine derivative that inhibits the NADP-dependent oxidoreductase, NQO1 (Ki = 1.72 µM), to destabilize microtubules and disrupt mitosis. At 50 µM, it directly affects tubulin polymerization in Xenopus egg extracts without interfering with the activity of Cdk1, DNA replication, or actin...
| Schlagworte: | NG72, (2R)-2-[[6-[(3-aminophenyl)thio]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
| Anwendung: | Cell-permeable NQO1 inhibitor |
| CAS | 361431-33-6 |
| MW: | 386.5 D |
ab 73,00 €
(±)-Dunnione
Artikelnummer: Cay21943-1
(±)-Dunnione is a naturally occurring naphthoquinone with diverse biological activities. (±)-Dunnione also reduces the growth of T. cruzi epimastigotes (IC50 = 4.01 µM). It is a substrate for NAD(P)H:quinone oxidoreductase 1 (NQO1) that increases production of reactive oxygen species (ROS) and induces cell death of...
| Schlagworte: | NSC 95403, 2,3-dihydro-2,3,3-trimethyl-naphtho[1,2-b]furan-4,5-dione |
| Anwendung: | NQO1 substrate |
| CAS | 521-49-3 |
| MW: | 242.3 D |
ab 93,00 €
Anti-NQO1
Artikelnummer: E-AB-16011.120
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of...
| Schlagworte: | Anti-DTD, Anti-QR1, Anti-NQO1, Anti-DIA4, EC=1.6.5.2, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Quinone reductase 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-NQO1 (human)
Artikelnummer: AG-25A-0105-C100
Recognizes human NQO1. Detects a band of about 30kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron...
| Schlagworte: | NAD(P)H Dehydrogenase (Quinine) 1 (NQO1), Quinone Reductase 1 (QR1), DT-Diaphorase (DTD), Azoreductase, Phylloquinone... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
182,00 €
Anti-NQO1, C-terminal
Artikelnummer: ARG63196.100
Protein function: The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. [The UniProt...
| Schlagworte: | Anti-QR1, Anti-DTD, Anti-NQO1, Anti-DIA4, EC=1.6.5.2, Anti-Azoreductase, Anti-DT-diaphorase, Anti-Quinone reductase 1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse, dog |
871,00 €