Zu "K00288" wurden 34 Artikel gefunden!

TH9619

Artikelnummer: Cay45380-1

An MTHFD inhibitor (IC50s = 16, 47, and 47 nM, respectively), inhibits nuclear MTHFD2 and cytoplasmic MTHFD1 but not mitochondrial MTHFD2, leading to an increase in 10-CHO-THF, thymidylate depletion, and cell death, selective for MTHFD1 and MTHFD2 over a panel of 44 kinases at 12 µM, reduces proliferation in a panel...

Schlagworte:	N-[[5-[[2-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)acetyl]amino]-3-fluoro-2-pyridinyl]carbonyl]-L-glutamic acid
Anwendung:	MTHFD inhibitor
CAS	2379556-22-4
MW:	451.37 D

ab 133,00 €

LY345899

Artikelnummer: Cay36627-1

LY345899 is an inhibitor of methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) and MTHFD2 (IC50s = 96 and 663 nM, respectively). It decreases the NADPH-to-NADP+ (NADPH/NADP+) and reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratios and increases the production of reactive oxygen species (ROS) in HCT116,...

Schlagworte:	N-[4-(3-amino-1,2,5,6,6a,7-hexahydro-1,9-dioxoimidazo[1,5-f]pteridin-8(9H)-yl)benzoyl]-L-glutamic acid
Anwendung:	MTHFD inhibitor
CAS	10538-99-5
MW:	471.4 D

ab 62,00 €

Anti-MTHFD1, Internal

Artikelnummer: ARG64753.100

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=3.5.4.9, EC=6.3.4.3, EC=1.5.1.5
Anwendung:	ELISA, WB
Wirt:	Goat
Spezies-Reaktivität:	human

871,00 €

Artikelnummer: A305-285A

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=3.5.4.9, EC=1.5.1.5, EC=6.3.4.3
Anwendung:	WB, IP
Wirt:	Rabbit
Spezies-Reaktivität:	human, mouse

ab 165,00 €

Artikelnummer: A305-286A

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=3.5.4.9, EC=1.5.1.5, EC=6.3.4.3
Anwendung:	WB, IP
Wirt:	Rabbit
Spezies-Reaktivität:	human, mouse

ab 165,00 €

Artikelnummer: NSJ-R35615-100UG

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=1.5.1.5, EC=3.5.4.9, EC=6.3.4.3, MTHFD1 Antibody
Anwendung:	WB, ELISA (peptide)
Wirt:	Goat
Spezies-Reaktivität:	human

836,00 €

Artikelnummer: ATA-HPA000704.100

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 87%

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=6.3.4.3, EC=1.5.1.5, EC=3.5.4.9
Anwendung:	IHC, WB
Wirt:	Rabbit
Spezies-Reaktivität:	human, mouse, rat

ab 330,00 €

Artikelnummer: ATA-HPA001290.100

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 90% and to rat: 90%

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=6.3.4.3, EC=1.5.1.5, EC=3.5.4.9
Anwendung:	IHC, WB
Wirt:	Rabbit
Spezies-Reaktivität:	human

ab 330,00 €

Artikelnummer: ATA-HPA050052.100

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 92% and to rat: 92%

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=6.3.4.3, EC=1.5.1.5, EC=3.5.4.9
Anwendung:	IHC, WB
Wirt:	Rabbit
Spezies-Reaktivität:	human

ab 330,00 €

Artikelnummer: ATA-HPA015006.100

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 95% and to rat: 95%

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, EC=6.3.4.3, EC=1.5.1.5, EC=3.5.4.9
Anwendung:	IHC, WB
Wirt:	Rabbit
Spezies-Reaktivität:	human, mouse, rat

463,00 €

Anti-C-1-tetrahydrofolate synthase / MTHFD1

Artikelnummer: NSJ-RQ7319

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Monofunctional C1-tetrahydrofolate synthase, mitochondrial also known as formyltetrahydrofolate synthetase, is an enzyme that in humans is encoded by the MTHFD1L gene (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like). The protein encoded by this...

Schlagworte:	Anti-MTHFC, Anti-MTHFD1, C-1-tetrahydrofolate synthase Antibody / MTHFD1
Anwendung:	WB, IHC (paraffin), IF, FC, Direct ELISA
Wirt:	Rabbit
Spezies-Reaktivität:	human, mouse, rat

790,00 €