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L-2-Hydroxyglutaric acid
L-2-Hydroxyglutaric acid

Artikelnummer: TGM-T13749-10mg

Description: L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Additionally, it obstructs histone demethylases, thereby encouraging histone...
Schlagworte: (S)-2-Hydroxyglutaric acid
Anwendung: Metabolite
CAS 13095-48-2
MW: 148.11 D
ab 77,00 €
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alpha-Hydroxyglutaric Acid
alpha-Hydroxyglutaric Acid

Artikelnummer: TGM-T36624-10mg

Description: alpha-Hydroxyglutaric Acid is a natural product for research related to life sciences. The catalog number is T36624 and the CAS number is 2889-31-8.This compound is unstable in powder form and other related salt forms are recommended. Target: Others. Smiles: OC(CCC(O)=O)C(O)=O
Anwendung: L2HGDH / D2HGDH substrate
CAS 2889-31-8
MW: 148.114 D
ab 248,00 €
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L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH), bovine, recombinant
L-2-hydroxyglutarate dehydrogenase, mitochondrial...

Artikelnummer: CSB-EP012709BO.1

Organism: Bos taurus (Bovine). Source: E.coli. Expression Region: 53-463aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: IIGGGIVGLA SARALILRHP ALSIGVLEKE KNLAVHQTGH NSGVIHSGIY YKPESLKAKL CVQGAALIYE YCNQKGISYK QCGKLIVAVE QEEIPRLQAL YERGLQNGVQ...
Schlagworte: L2HGDH, Duranin, EC=1.1.99.2, L-2-hydroxyglutarate dehydrogenase, mitochondrial, Recombinant Bovine L-2-hydroxyglutarate...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: bovine
MW: 61.7 kD
ab 364,00 €
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L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH), human, recombinant
L-2-hydroxyglutarate dehydrogenase, mitochondrial...

Artikelnummer: CSB-EP864008HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 52-463aa. Protein Length: Full Length of Mature Protein. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: VIVGGGIVGL ASARALILRH PSLSIGVLEK EKDLAVHQTG HNSGVIHSGI YYKPESLKAK LCVQGAALLY EYCQQKGISY KQCGKLIVAV EQEEIPRLQA LYEKGLQNGV...
Schlagworte: L2HGDH, Duranin, C14orf160, EC=1.1.99.2, L-2-hydroxyglutarate dehydrogenase, mitochondrial, Recombinant Human...
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 61.3 kD
ab 219,00 €
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alpha-Hydroxyglutaric Acid
alpha-Hydroxyglutaric Acid

Artikelnummer: Cay25894-10

alpha-Hydroxyglutaric acid (2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased levels of L-2-hydroxyglutaric acid (Cay-21123). 2-HG...
Schlagworte: 2-HG, 2-Hydroxyglutaric Acid, 2-hydroxy-pentanedioic acid
Anwendung: L2HGDH / D2HGDH substrate
CAS 2889-31-8
MW: 148.1 D
ab 137,00 €
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Octyl-alpha-hydroxyglutarate
Octyl-alpha-hydroxyglutarate

Artikelnummer: Cay16365-5

alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
Schlagworte: Octyl-2-HG, 2-hydroxy-pentanedioic acid, 1-octyl ester
Anwendung: Cell-permeable 2-HG derivative
CAS 2097068-39-6
MW: 260.3 D
ab 74,00 €
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L-alpha-Hydroxyglutaric Acid
L-alpha-Hydroxyglutaric Acid

Artikelnummer: Cay21123-10

L-alpha-Hydroxyglutaric acid (L-2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate (alpha-ketoglutarate) by L-2-hydroxyglutarate dehydrogenase, and mutations in this enzyme lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased L-2-HG levels. L-2-HG is structurally...
Schlagworte: 2(S)-HG, 2(S)-Hydroxyglutaric Acid, L-2-HG, L-2-Hydroxyglutaric Acid, 2S-hydroxy-pentanedioic acid
Anwendung: Metabolite
CAS 13095-48-2
MW: 148.1 D
ab 44,00 €
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Anti-L2HGDH
Anti-L2HGDH

Artikelnummer: ATA-HPA065409.100

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 81% and to rat: 78%
Schlagworte: Anti-L2HGDH, Anti-Duranin, Anti-C14orf160, EC=1.1.99.2, Anti-L-2-hydroxyglutarate dehydrogenase, mitochondrial
Anwendung: ICC, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 358,00 €
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Anti-L2HGDH
Anti-L2HGDH

Artikelnummer: ATA-HPA069708.100

Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to rat: 83%
Schlagworte: Anti-L2HGDH, Anti-Duranin, Anti-C14orf160, EC=1.1.99.2, Anti-L-2-hydroxyglutarate dehydrogenase, mitochondrial
Anwendung: ICC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 358,00 €
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NEU
Anti-Y45G12B.3
Anti-Y45G12B.3

Artikelnummer: CSB-PA863095XA01CXY.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Schlagworte: Anti-Y45G12B.3, EC=1.1.99.2, Anti-L-2-hydroxyglutarate dehydrogenase, mitochondrial, Y45G12B.3 Antibody
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: Caenorhabditis elegans
ab 1.529,00 €
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L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH), recombinant human
L-2-hydroxyglutarate dehydrogenase, mitochondrial...

Artikelnummer: CSB-EP864008HU_F2_.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 52-441aa. Protein Length: Full Length of Mature Protein of Isoform 2. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: VIVGGGIVGL ASARALILRH PSLSIGVLEK EKDLAVHQTG HNSGVIHSGI YYKPESLKAK LCVQGAALLY EYCQQKGISY KQCGKLIVAV EQEEIPRLQA...
Schlagworte: L2HGDH, Duranin, C14orf160, EC=1.1.99.2, L-2-hydroxyglutarate dehydrogenase, mitochondrial
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 59.5 kD
ab 219,00 €
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L2HGDH (human), recombinant protein
L2HGDH (human), recombinant protein

Artikelnummer: ABS-PP-12600.20

Schlagworte: L-2-hydroxyglutarate dehydrogenase, mitochondrial, Duranin, Recombinant Human L2HGDH Protein
Exprimiert in: E.coli
Ursprungsart: human
MW: 37 kD
ab 90,00 €
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