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Anti-Recombinant SPR, clone A748
Artikelnummer: E-AN302028L.100
SPR can catalyze the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.Defects in SPR are the cause of dystonia DOPA-responsive due to sepiapterin reductase deficiency (DRDSPRD). In the majority of cases, patients manifest progressive psychomotor retardation,...
| Schlagworte: | Anti-SPR, Anti-Sepiapterin reductase, Recombinant SPR Monoclonal Antibody |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
SPRi 3
Artikelnummer: Cay30950-1
SPRi 3 is an inhibitor of sepiapterin reductase (SPR), an enzyme that catalyzes the formation of tetrahydrobiopterin (BH4), with IC50 values of 62 and 14 nM for the recombinant human and rat enzymes, respectively. It is selective for SPR over GTP cyclohydroxylase 1 (GCH1) in primary mouse dorsal root ganglia sensory...
| Schlagworte: | N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy-acetamide |
| Anwendung: | Sepiapterin reductase (SPR) inhibitor |
| CAS | 1292285-54-1 |
| MW: | 262.3 D |
ab 67,00 €
Anti-SPR
Artikelnummer: E-AB-13034.120
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on...
| Schlagworte: | Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-SPR
Artikelnummer: NSJ-F52016-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A...
| Schlagworte: | Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-SPR
Artikelnummer: E-AB-16217.120
This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on...
| Schlagworte: | Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-SPR
Artikelnummer: ATA-HPA039505.100
Protein function: Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 74% and to rat: 73%
| Schlagworte: | Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Human SPR (Sepiapterin Reductase) ELISA Kit
Artikelnummer: ELK-ELK3702.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SPR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SPR. Next,...
| Schlagworte: | SPR, Sepiapterin reductase |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Sepiapterin reductase (SPR), human, recombinant
Artikelnummer: CSB-EP022605HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-261aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS...
| Schlagworte: | SPR, EC=1.1.1.153, Sepiapterin reductase, Recombinant Human Sepiapterin reductase (SPR) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 32 kD |
ab 292,00 €
Anti-SPR
Artikelnummer: CSB-PA214577.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPR. Antigen Species: Human
| Schlagworte: | Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, OTTHUMP00000160199 antibody, SDR38C1 antibody, Sepiapterin reductase... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-SPR
Artikelnummer: CSB-PA262747.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPR. Antigen Species: Human
| Schlagworte: | Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, OTTHUMP00000160199 antibody, SDR38C1 antibody, Sepiapterin reductase... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
SPR inhibitor 3
Artikelnummer: TGM-T16924-10mg
Description: SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a...
| Schlagworte: | SPRi3 |
| Anwendung: | SPR inhibitor |
| CAS | 1292285-54-1 |
| MW: | 262.3 D |
ab 64,00 €
NEU
![Anti-SPR [4F5] Monoclonal Antibody -Knockout Validated](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "Anti-SPR [4F5] Monoclonal Antibody -Knockout Validated")
Anti-SPR [4F5] Monoclonal Antibody -Knockout Validated
Artikelnummer: G-AGMB06743.100
[KO] SPR Monoclonal Antibody from Assay Genie is a high quality antibody for research use only. Protein Function: Catalyzes the final one or two reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin [The Uniprot Consortium]
| Schlagworte: | Anti-SPR, Anti-Sepiapterin reductase |
| Anwendung: | WB, IHC-P, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat |
ab 378,00 €