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SPR inhibitor 3
SPR inhibitor 3

Artikelnummer: TGM-T16924-10mg

Description: SPR inhibitor 3 is an effective sepiapterin reductase inhibitor. SPR inhibitor 3 decreases neuropathic and inflammatory pain through a reduction of BH4 levels. SPR inhibitor 3 shows a high binding affinity to human SPR in a cell-free assay (IC50=74 nM) and efficiently reduces biopterin levels in a...
Schlagworte: SPRi3
Anwendung: SPR inhibitor
CAS 1292285-54-1
MW: 262.3 D
ab 67,00 €
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Sepiapterin reductase (SPR), human, recombinant
Sepiapterin reductase (SPR), human, recombinant

Artikelnummer: CSB-EP022605HU.1

Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-261aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS...
Schlagworte: SPR, EC=1.1.1.153, Sepiapterin reductase, Recombinant Human Sepiapterin reductase (SPR)
Anwendung: Activity not tested
Exprimiert in: E.coli
Ursprungsart: human
MW: 32 kD
ab 292,00 €
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Anti-SPR
Anti-SPR

Artikelnummer: CSB-PA214577.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPR. Antigen Species: Human
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, OTTHUMP00000160199 antibody, SDR38C1 antibody, Sepiapterin reductase...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 167,00 €
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Anti-SPR
Anti-SPR

Artikelnummer: CSB-PA262747.100

Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: SPR. Antigen Species: Human
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, OTTHUMP00000160199 antibody, SDR38C1 antibody, Sepiapterin reductase...
Anwendung: ELISA, WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 167,00 €
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SPRi 3
SPRi 3

Artikelnummer: Cay30950-1

SPRi 3 is an inhibitor of sepiapterin reductase (SPR), an enzyme that catalyzes the formation of tetrahydrobiopterin (BH4), with IC50 values of 62 and 14 nM for the recombinant human and rat enzymes, respectively. It is selective for SPR over GTP cyclohydroxylase 1 (GCH1) in primary mouse dorsal root ganglia sensory...
Schlagworte: N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxy-acetamide
Anwendung: Sepiapterin reductase (SPR) inhibitor
CAS 1292285-54-1
MW: 262.3 D
ab 61,00 €
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Anti-SPR
Anti-SPR

Artikelnummer: E-AB-13034.120

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on...
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Polyclonal Antibody
Anwendung: WB, IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human
ab 89,00 €
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Anti-SPR
Anti-SPR

Artikelnummer: NSJ-F52016-0.08ML

In 1X PBS, pH 7.4, with 0.09% sodium azide. SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A...
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Antibody
Anwendung: WB, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 350,00 €
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Anti-SPR
Anti-SPR

Artikelnummer: E-AB-16217.120

This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on...
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Polyclonal Antibody
Anwendung: WB, IHC, ELISA
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 89,00 €
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Anti-SPR
Anti-SPR

Artikelnummer: ATA-HPA039505.100

Protein function: Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 74% and to rat: 73%
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase
Anwendung: ICC, IHC, WB
Wirt: Rabbit
Spezies-Reaktivität: human
ab 358,00 €
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Human SPR (Sepiapterin Reductase) ELISA Kit
Human SPR (Sepiapterin Reductase) ELISA Kit

Artikelnummer: ELK-ELK3702.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human SPR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human SPR. Next,...
Schlagworte: SPR, Sepiapterin reductase
Anwendung: ELISA
Spezies-Reaktivität: human
ab 374,00 €
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NEU
Anti-SPR
Anti-SPR

Artikelnummer: CSB-PA022605ZA01HU.2

Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
Schlagworte: Anti-SPR, EC=1.1.1.153, Anti-Sepiapterin reductase, SPR Antibody
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: Homo sapiens (Human)
ab 1.529,00 €
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SPR (human), recombinant protein
SPR (human), recombinant protein

Artikelnummer: ABS-PP-3944.20

Schlagworte: Sepiapterin reductase, SPR, Recombinant Human SPR Protein
Exprimiert in: E.coli
Ursprungsart: human
MW: 29 kD
ab 90,00 €
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