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Zu "K00069" wurden 46 Artikel gefunden!
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Artikelnummer: NSJ-RQ5486
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The HPGD gene encodes a member of the short-chain non-metalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular...
Schlagworte: | Anti-PGDH1, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-Eicosanoid/docosanoid dehydrogenase [NAD(+)],... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: Cay14650-1
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
Schlagworte: | 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid |
Anwendung: | Bioactive lipid assays |
CAS | 363-23-5 |
MW: | 352.5 D |
ab 104,00 €
Artikelnummer: Cay18040-5
The enzyme 15-hydroxy prostaglandin dehydrogenase (15-PGDH) initiates the catabolism of PGs and related eicosanoids. SW033291 is a potent inhibitor of 15-PGDH (Ki = ~0.1 nM) that has activity in vivo. It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after intraperitoneal injection....
Schlagworte: | 2-(butylsulfinyl)-4-phenyl-6-(2-thienyl)-thieno[2,3-b]pyridine-3-amine |
Anwendung: | 15-PGDH inhibitor |
CAS | 459147-39-8 |
MW: | 412.6 D |
ab 61,00 €
Artikelnummer: Cay160615-1
NAD+-dependent 15-PGDH catalyzes the oxidation of prostaglandins to 15-keto metabolites, which have greatly reduced biological activity. Human NAD+-dependent 15-PGDH is a 266 amino acid protein with a molecular weight of 29 kDa and is expressed in multiple tissues including lung, placenta, and kidney. The enzyme...
Schlagworte: | Anti-PGDH1, Anti-15-PGDH, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-Prostaglandin dehydrogenase 1, Anti-Short... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, bovine, guinea pig, baboon |
422,00 €
Artikelnummer: Cay14049-10
15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH) is a key enzyme involved in the inactivation of PGs and related eiscosanoids. It functions by catalyzing the oxidation of primary PGs to their 15-keto metabolites. Two types of 15-hydroxy PGDH have been identified: type-I is NAD+-dependent primarily using...
Schlagworte: | 2-[[(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)thio]methyl]-benzonitrile |
Anwendung: | 15-PGDH inhibitor |
CAS | 355827-05-3 |
MW: | 345.2 D |
ab 77,00 €
Artikelnummer: ARG56503.250
Protein function: Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. [The UniProt Consortium]
Schlagworte: | Anti-HPGD, Anti-PGDH1, Anti-15-PGDH, EC=1.1.1.141, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, bovine, guinea pig, baboon |
656,00 €
Artikelnummer: ARG63685.100
Protein function: Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. [The UniProt Consortium]
Schlagworte: | Anti-HPGD, Anti-PGDH1, Anti-15-PGDH, EC=1.1.1.141, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin... |
Anwendung: | ELISA, IHC (paraffin), WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
784,00 €
Artikelnummer: NSJ-R33680-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Hydroxyprostaglandin dehydrogenase 15, Prostaglandin dehydrogenase 1, HPGD Protein function: Primary enzyme catalyzing the conversion of hydroxylated arachidonic acid species to their...
Schlagworte: | Anti-PGDH1, Anti-15-PGDH, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin dehydrogenase [NAD(+)],... |
Anwendung: | WB, IHC, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
755,00 €
Artikelnummer: E-AB-15101.120
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal...
Schlagworte: | Anti-HPGD, Anti-PGDH1, Anti-15-PGDH, EC=1.1.1.141, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Artikelnummer: Cay70130-1
Prostaglandins are rapidly inactivated in vivo by the action of 15-hydroxy prostaglandin dehydrogenase (15-hydroxy PGDH). This enzyme oxidizes the 15-hydroxyl group and hydrogenates the 13,14-double bond, producing 13,14-dihydro-15 keto metabolites with greatly reduced biological activity. CAY10397 is a selective...
Schlagworte: | CK47A, 5-[[4-(ethoxycarbonyl)phenyl]azo]-2-hydroxy-benzeneacetic acid |
Anwendung: | 15-hydroxy PGDH inhibitor |
CAS | 78028-01-0 |
MW: | 328.3 D |
ab 80,00 €
Artikelnummer: Cay20475-1
ML-148 is an inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) with an IC50 value of 56 nM. It demonstrates selectivity for 15-PGDH when profiled across a panel of related dehydrogenase or reductase enzymes.Formal Name: [1-(3-methylphenyl)-1H-benzimidazol-5-yl]-1-piperidinyl-methanone. CAS Number:...
Schlagworte: | [1-(3-methylphenyl)-1H-benzimidazol-5-yl]-1-piperidinyl-methanone |
Anwendung: | Potent, selective, competitive HPGD inhibitor |
CAS | 451496-96-1 |
MW: | 319.4 D |
ab 50,00 €
Artikelnummer: E-AB-40343.120
This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal...
Schlagworte: | Anti-Hpgd, Anti-Pgdh1, Anti-15-PGDH, EC=1.1.1.141, Anti-Prostaglandin dehydrogenase 1, Anti-15-hydroxyprostaglandin... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
ab 63,00 €