Zu "K00058" wurden 57 Artikel gefunden!
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Anti-PHGDH / D-3-phosphoglycerate dehydrogenase
Artikelnummer: NSJ-FY12088
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PHGDH antibody detects D-3-phosphoglycerate dehydrogenase, encoded by the PHGDH gene. D-3-phosphoglycerate dehydrogenase is a key enzyme in the serine biosynthesis pathway, catalyzing the conversion of 3-phosphoglycerate to...
| Schlagworte: | Anti-PHGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate dehydrogenase, PHGDH... |
| Anwendung: | ELISA, FC, IP, IF, IHC, ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-PGDH/PHGDH Monoclonal Antibody
Artikelnummer: E-AN200135P.100
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with...
| Schlagworte: | PGDH3, PHGDH, 3-PGDH, Malate dehydrogenase, 2-oxoglutarate reductase, D-3-phosphoglycerate dehydrogenase, PGDH/PHGDH... |
| Anwendung: | FCM, ICC/IF |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
CBR-5884
Artikelnummer: Cay19236-5
CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 µM. It does not affect other NAD+-dependent dehydrogenases, including lactate dehydrogenase and malate dehydrogenase 1. CBR-5884 inhibits the proliferation of...
| Schlagworte: | 5-[(2-furanylcarbonyl)amino]-3-methyl-4-thiocyanato-2-thiophenecarboxylic acid, ethyl ester |
| Anwendung: | PHGDH inhibitor |
| CAS | 681159-27-3 |
| MW: | 336.4 D |
ab 38,00 €
NCT-503
Artikelnummer: Cay19718-5
NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 µM. It has been shown to reduce the production of glucose-derived serine in cells and to suppress the growth of PHGDH-dependent MDA-MB-468 cancer cells both in...
| Schlagworte: | N-(4,6-dimethyl-2-pyridinyl)-4-[[4-(trifluoromethyl)phenyl]methyl]-1-piperazinecarbothioamide |
| Anwendung: | PHGDH inhibitor |
| CAS | 1916571-90-8 |
| MW: | 408.5 D |
ab 49,00 €
PHGDH, human recombinant protein, C-terminal His-tag
Artikelnummer: BPS-71079
Human phosphoglycerate dehydro-genase (PGDH), also known as PDG, amino-acids 1 - 533 (end) (GenBank Accession No. NM_006623) with C-terminal His tag, MW = 57.5 kDa, expressed in an E. coli expression system.
| Schlagworte: | PHGDH, PGDH3, 3-PGDH, Malate dehydrogenase, 2-oxoglutarate reductase, D-3-phosphoglycerate dehydrogenase, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 57.5 kD |
603,00 €
PHGDH-inactive
Artikelnummer: Cay19717-5
PHGDH-inactive is an inactive analog of the 3-phosphoglycerate dehydrogenase (PHGDH) inhibitors NCT-502 (Cay-19716) and NCT-503 (Cay-19718). Unlike the inhibitors, PHGDH-inactive does not inhibit PHGDH in vitro (IC50s = >57, 3.7, and 2.5 µM for PHGDH-inactive, NCT-502, and NCT-503, respectively), block serine...
| Schlagworte: | 3-Phosphoglycerate Dehydrogenase-inactive, N-(4,6-dimethyl-2-pyridinyl)-4-(4-pyridinyl)-1-piperazinecarbothioamide |
| Anwendung: | PHGDH inhibitor control |
| CAS | 1914971-16-6 |
| MW: | 327.5 D |
ab 73,00 €
Anti-PHGDH
Artikelnummer: A304-732A-T
Protein function: Catalyzes the reversible oxidation of 3-phospho-D- glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate....
| Schlagworte: | Anti-PGDH3, Anti-PHGDH, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
NCT-502
Artikelnummer: Cay19716-1
NCT-502 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 3.7 µM. It is inactive against a panel of other dehydrogenases and shows minimal cross reactivity with G protein-coupled receptors. NCT-502 reversibly blocks the...
| Schlagworte: | N-(4,6-dimethyl-2-pyridinyl)-4-[5-(trifluoromethyl)-2-pyridinyl]-1-piperazinecarbothioamide |
| Anwendung: | PHGDH inhibitor |
| CAS | 1542213-00-2 |
| MW: | 395.4 D |
ab 49,00 €
Anti-PHGDH
Artikelnummer: NSJ-F48339-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. 3-Phosphoglycerate dehydrogenase (PHGDH) catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
| Schlagworte: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, EC=1.1.1.95, Anti-D-3-phosphoglycerate dehydrogenase, PHGDH Antibody |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-PHGDH
Artikelnummer: NSJ-F48338-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. 3-Phosphoglycerate dehydrogenase catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.
| Schlagworte: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, EC=1.1.1.95, Anti-D-3-phosphoglycerate dehydrogenase, PHGDH Antibody |
| Anwendung: | WB, IHC, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-PHGDH, clone CL0555
Artikelnummer: ATA-AMAb90786.100
Protein function: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate....
| Schlagworte: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-PHGDH
Artikelnummer: ATA-HPA024031.100
Protein function: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate and the reversible oxidation of (S)-malate to oxaloacetate....
| Schlagworte: | Anti-PHGDH, Anti-PGDH3, Anti-3-PGDH, Anti-Malate dehydrogenase, Anti-2-oxoglutarate reductase, Anti-D-3-phosphoglycerate... |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €