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LDH Cytotoxicity Assay Kit
LDH Cytotoxicity Assay Kit

Artikelnummer: Cay601170-480

Necrosis is accompanied by mitochondrial swelling and increased plasma membrane permeability, while apoptosis involves an articulated breakdown of the cell into membrane-bound apoptotic bodies. Lactate dehydrogenase (LDH) is a soluble cytosolic enzyme that is released into the culture medium following loss of...
Schlagworte: Lactate Dehydrogenase Cytotoxicity Assay Kite, raplacement of Cay10008882
Anwendung: Cell based assays
Reaktivität: Broad
ab 83,00 €
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Sodium Oxamate
Sodium Oxamate

Artikelnummer: Cay19057-5

Sodium oxamate is a derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis. Because cancer cells produce a large amount of energy via aerobic glycolysis, sodium oxamate has been studied as an inhibitor of carbohydrate metabolism in various...
Schlagworte: Oxalic Acid monoamide, Oxamic Acid, 2-amino-2-oxo-acetic acid, monosodium salt
Anwendung: Glycolysis disruptor, Lactate dehydrogenase inhibitor
CAS 565-73-1
MW: 111 D
ab 58,00 €
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GSK2837808A
GSK2837808A

Artikelnummer: Cay20626-1

GSK2837808A is a potent inhibitor of lactate dehydrogenase (LDH) A and B (IC50s = 2.6 and 0.43 nM, for human recombinant LDHA and LDHB, respectively). It inhibits lactate production in Snu398 hepatocellular carcinoma cells in which LDHB expression is undetectable (EC50 = 400 nM). GSK2837808A (10 µM) reduces glucose...
Schlagworte: 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-benzoic acid
Anwendung: LDHA inhibitor
CAS 1445879-21-9
MW: 649.6 D
ab 44,00 €
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LDH Positive Control
LDH Positive Control

Artikelnummer: Cay10009321-1

Anwendung: Standard
14,00 €
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Amplite(TM) Colorimetric L-Lactate Dehydrogenase (LDH) Assay Kit
Amplite(TM) Colorimetric L-Lactate Dehydrogenase (LDH)...

Artikelnummer: ABD-13813

Ex: 575 nm. Lactate dehydrogenase (LDH) is an oxidoreductase enzyme that catalyzes the interconversion of pyruvate and lactate. LDH is present in cytosol of a wide variety of organisms, including animals and plants. Cells release LDH into the bloodstream after tissue damage or red blood cell hemolysis. Since LDH is...
Anwendung: Cell metabolism assay
346,00 €
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NHI 2
NHI 2

Artikelnummer: Cay30201-1

NHI 2 is an inhibitor of lactate dehydrogenase A (LDHA, IC50 = 14.7 µM). It is selective for LDHA over LDHB (IC50 = 55.8 µM). It inhibits lactate production in HeLa cells when used at concentrations of 100 and 200 µM. NHI 2 is cytotoxic to HeLa cells (IC50 = 33.4 µM).
Schlagworte: 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylic acid, methyl ester
Anwendung: Lactate dehydrogenase A (LDHA) inhibitor
CAS 1269802-97-2
MW: 335.3 D
ab 32,00 €
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Galloflavin
Galloflavin

Artikelnummer: Cay14846-5

Galloflavin is an inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 µM, respectively). It has been shown to prevent proliferation of many different cancer cell lines in vitro by blocking glycolysis and ATP production.
Schlagworte: NSC 107022, 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione
Anwendung: LDH inhibitor
CAS 568-80-9
MW: 278.2 D
ab 32,00 €
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AZ 33
AZ 33

Artikelnummer: Cay25444-1

AZ 33 is an inhibitor of lactate dehydrogenase A (LDHA, Kd = 0.093 µM, IC50 = 0.5 µM). It is selective for LDHA over LDHB in an NADH competition assay using recombinant enzymes (IC50s = 0.54 and 3.6 µM, respectively). AZ 33 is cell-impermeable and lacks cytotoxicity against HeLa cervical cancer cells (IC50 = >500 µM).
Schlagworte: 2-[[4-[4-[[3-[(2-methyl-6-benzothiazolyl)amino]-3-oxopropyl]amino]-4-oxobutyl]phenyl]methyl]-propanedioic acid
Anwendung: LDHA inhibitor
CAS 1370290-34-8
MW: 497.6 D
ab 32,00 €
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LDHA, Human Recombinant Protein
LDHA, Human Recombinant Protein

Artikelnummer: BPS-71081

Human Lactate dehydrogenase A (LDHA), GenBank Accession No. NM_005566), full length [2-332(end)] with N-terminal His-tag, MW= 37.5kDa, expressed in an E.coli expression system.
Schlagworte: LDHA, PIG19, LDH-M, LDH-A, EC=1.1.1.27, LDH muscle subunit, L-lactate dehydrogenase A chain, Renal carcinoma antigen...
Anwendung: Enzyme kinetics, Screening inhibitors, Selectivity profiling
Reaktivität: Human
MW: 37.5 kD
468,00 €
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GSK2837808A
GSK2837808A

Artikelnummer: AG-CR1-3685-M005

Schlagworte: 3-((3-(N-Cyclopropylsulfamoyl)-7-(2,4-dimethoxypyrimidin-5-yl)quinolin-4-yl)amino)-5-(3,5-difluorophenoxy)benzoic acid
Anwendung: Potent, selective cell-permeable LDHA inhibitor
CAS 1445879-21-9
MW: 649.6 D
ab 44,00 €
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LDHB, human recombinant protein, N-terminal His-tag
LDHB, human recombinant protein, N-terminal His-tag

Artikelnummer: BPS-71078

Human lactate dehydrogenase B (LDHB) amino-acids 2 - 334 (end) (GenBank Accession No. NM_002300) with N-terminal His tag, MW = 37.5 kDa, expressed in an E. coli expression system.
Schlagworte: LDHB, LDH-H, LDH-B, EC=1.1.1.27, LDH heart subunit, L-lactate dehydrogenase B chain, Renal carcinoma antigen NY-REN-46
Anwendung: Enzyme kinetics, inhibitor screening, Selectivity profiling
Reaktivität: Human
MW: 37.5 kD
468,00 €
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Human LDHA (Lactate Dehydrogenase A) CLIA Kit
Human LDHA (Lactate Dehydrogenase A) CLIA Kit

Artikelnummer: G-HUES00382.96

ELISA Type: CLIA. Sensitivity: 0.094 ng/mL. Range: 0.156--10 ng/mL. 0
Schlagworte: LDHA, PIG19, LDH-M, LDH-A, EC=1.1.1.27, LDH muscle subunit, L-lactate dehydrogenase A chain, Renal carcinoma antigen...
Anwendung: CLIA
Reaktivität: Human
629,00 €
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