Zu "K00016" wurden 233 Artikel gefunden!
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LDH Cytotoxicity Assay Kit
Artikelnummer: Cay601170-96
Necrosis is accompanied by mitochondrial swelling and increased plasma membrane permeability, while apoptosis involves an articulated breakdown of the cell into membrane-bound apoptotic bodies. Lactate dehydrogenase (LDH) is a soluble cytosolic enzyme that is released into the culture medium following loss of...
| Schlagworte: | Lactate Dehydrogenase Cytotoxicity Assay Kit |
| Anwendung: | Cell based assays |
| Spezies-Reaktivität: | broad |
ab 295,00 €
Anti-Recombinant Lactate Dehydrogenase, clone 1F8
Artikelnummer: E-AN301068L.100
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria....
| Schlagworte: | Anti-LDHA, Anti-LDH muscle subunit, Anti-L-lactate dehydrogenase A chain, Anti-Renal carcinoma antigen NY-REN-59,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Recombinant Lactate Dehydrogenase Isoenzyme V, clone...
Artikelnummer: E-AN301095L.100
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria....
| Schlagworte: | Anti-LDHA, Anti-LDH muscle subunit, Anti-L-lactate dehydrogenase A chain, Anti-Renal carcinoma antigen NY-REN-59,... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 258,00 €
Anti-Recombinant LDHC, clone A443
Artikelnummer: E-AN301735L.100
Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. In particular, recent...
| Schlagworte: | Anti-LDHC, Anti-LDH-X, Anti-LDH testis subunit, Anti-Cancer/testis antigen 32, Anti-L-lactate dehydrogenase C chain,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
LDH-IN-1
Artikelnummer: Cay44281-1
LDH-IN-1 is an inhibitor of lactate dehydrogenase A (LDHA) and LDHB (IC50s = 0. and 0. µM, respectively). It is selective for LDHA and LDHB over malate dehydrogenase (MDH) and isocitrate dehydrogenase 1 (IDH1, IC50s = 37. and 29. µM, respectively). LDH-IN-1 is cytotoxic to A-673 sarcoma and MiaPaCa-2 pancreatic...
| Schlagworte: | Lactate Dehydrogenase Inhibitor 1, Lactate Dehydrogenase-IN-1, LDH Inhibitor 1 |
| Anwendung: | LDHA / LDHB inhibitor |
| CAS | 1964515-43-2 |
| MW: | 570.68 D |
ab 112,00 €
Sodium Oxamate
Artikelnummer: Cay19057-5
Sodium oxamate is a derivative of pyruvate that inhibits the conversion of pyruvate to lactate via lactate dehydrogenase, thus disrupting glycolysis. Because cancer cells produce a large amount of energy via aerobic glycolysis, sodium oxamate has been studied as an inhibitor of carbohydrate metabolism in various...
| Schlagworte: | Oxalic Acid monoamide, Oxamic Acid, 2-amino-2-oxo-acetic acid, monosodium salt |
| Anwendung: | Glycolysis disruptor, lactate dehydrogenase inhibitor |
| CAS | 565-73-1 |
| MW: | 111 D |
ab 88,00 €
GSK2837808A
Artikelnummer: Cay20626-1
GSK2837808A is a potent inhibitor of lactate dehydrogenase (LDH) A and B (IC50s = 2.6 and 0.43 nM, for human recombinant LDHA and LDHB, respectively). It inhibits lactate production in Snu398 hepatocellular carcinoma cells in which LDHB expression is undetectable (EC50 = 400 nM). GSK2837808A (10 µM) reduces glucose...
| Schlagworte: | 3-[[3-[(cyclopropylamino)sulfonyl]-7-(2,4-dimethoxy-5-pyrimidinyl)-4-quinolinyl]amino]-5-(3,5-difluorophenoxy)-benzoic acid |
| Anwendung: | LDHA inhibitor |
| CAS | 1445879-21-9 |
| MW: | 649.6 D |
ab 67,00 €
Galloflavin
Artikelnummer: Cay14846-5
Galloflavin is an inhibitor of both the A and B isoforms of lactate dehydrogenase (Kis = 5.46 and 15.06 µM, respectively). It has been shown to prevent proliferation of many different cancer cell lines in vitro by blocking glycolysis and ATP production.Formal Name:...
| Schlagworte: | NSC 107022, 3,8,9,10-tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione |
| Anwendung: | LDH inhibitor |
| CAS | 568-80-9 |
| MW: | 278.2 D |
ab 56,00 €
Amplite(TM) Colorimetric L-Lactate Dehydrogenase (LDH)...
Artikelnummer: ABD-13813
Ex: 575 nm. Lactate dehydrogenase (LDH) is an oxidoreductase enzyme that catalyzes the interconversion of pyruvate and lactate. LDH is present in cytosol of a wide variety of organisms, including animals and plants. Cells release LDH into the bloodstream after tissue damage or red blood cell hemolysis. Since LDH is...
| Anwendung: | Cell metabolism assay |
434,00 €
Amplite(TM) Fluorimetric L-Lactate Dehydrogenase (LDH)...
Artikelnummer: ABD-13812
Ex: 571 nm. Em: 585 nm. Lactate dehydrogenase (LDH) is an oxidoreductase enzyme that catalyzes the interconversion of pyruvate and lactate. LDH is present in cytosol of a wide variety of organisms, including animals and plants. Cells release LDH into the bloodstream after tissue damage or red blood cell hemolysis....
| Anwendung: | Cell metabolism assay |
434,00 €
NHI 2
Artikelnummer: Cay30201-10
NHI 2 is an inhibitor of lactate dehydrogenase A (LDHA, IC50 = 14.7 µM). It is selective for LDHA over LDHB (IC50 = 55.8 µM). It inhibits lactate production in HeLa cells when used at concentrations of 100 and 200 µM. NHI 2 is cytotoxic to HeLa cells (IC50 = 33.4 µM).Formal Name:...
| Schlagworte: | 1-hydroxy-6-phenyl-4-(trifluoromethyl)-1H-indole-2-carboxylic acid, methyl ester |
| Anwendung: | Lactate dehydrogenase A (LDHA) inhibitor |
| CAS | 1269802-97-2 |
| MW: | 335.3 D |
ab 49,00 €
LDHA, Human Recombinant Protein
Artikelnummer: BPS-71081
Human Lactate dehydrogenase A (LDHA), GenBank Accession No. NM_005566), full length [2-332(end)] with N-terminal His-tag, MW= 37.5kDa, expressed in an E.coli expression system.
| Schlagworte: | LDH-M, PIG19, LDH-A, LDH muscle subunit, L-lactate dehydrogenase A chain, Renal carcinoma antigen NY-REN-59, Cell... |
| Anwendung: | Enzyme kinetics, screening inhibitors, selectivity profiling |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 37.5 kD |
558,00 €